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Beto O'Rourke announced Thursday he is running for president, entering the 2020 race with a call for Americans to look past their differences in order to confront the challenges facing the country."This is a defining moment of truth for this country and for every single one of us," the 46-year-old Democratic former congressman from Texas said in a video announcing his candidacy. "The challenges that we face right now, the interconnected crises in our economy, our democracy and our climate have never been greater.""They will either consume us, or they will afford us the greatest opportunity to unleash the genius of the United States of America," he added.O'Rourke, who is starting a three-day swing through eastern Iowa on Thursday, said he will hold a kick-off rally for his campaign in El Paso, Texas, on March 30.His entrance into the race is the culmination of his two-year, out-of-nowhere rise from a back-bench congressman largely unknown outside El Paso to Democratic stardom as a record-breaking fundraiser, the subject of an HBO documentary and the target of two separate efforts to draft him into the presidential campaign. He joins a crowded field of more than a dozen Democrats vying for the party's nomination.In his announcement video, O'Rourke said he would run a "positive campaign that seeks to bring out the very best from every single one of us, that seeks to unite a very divided country.""We saw the power of this in Texas, where people allowed no difference, however great or however small, to stand between them and divide us," O'Rourke said.O'Rourke last year lost that race in Texas, a bid to oust Republican Sen. Ted Cruz. Still, the Senate race thrust O'Rourke, who served three terms in the House, into the national spotlight. He shattered fundraising records, ending with an million haul, and finished less than 3 percentage points behind Cruz -- much closer than other Democrats had come in recent years against Republicans in a state that's long been a GOP stronghold. But a presidential bid will be a much different test for O'Rourke, who will face serious pressure from the left for the first time in his political career.In an interview with CNN on Wednesday, O'Rourke said the 2020 campaign has "got to be about the big things that we hope to achieve and enact and do for one another."He said that "the most pressing, the most urgent, the most existential challenge of them all is climate. And the scientists, beyond a shadow of a doubt, know that we have at a maximum 12 years in order to enact significant change to meet that threat and reduce the consequences of the decisions that we made in the past -- the consequences that our kids and the generations that follow will bear."O'Rourke also began to lay out what he saw as his top priorities on the eve of his entrance into the 2020 race."Rewriting and signing into law immigration policies that reflect who we are and our values and what we know to be true, grounded in the facts," he said. "Making sure that everybody can see a doctor and live to their full potential. Listening to and then raising up rural communities that for so long have been left behind. Making sure people that are looking for work are able to find it -- that they're equipped with the skills and training and education necessary to maximize their potential. But also investing in people that are already working. ... There are so many people in this country working two and three jobs and struggling to make ends meet.""The destination cannot be Election Night, November 2020. The destination really has to be the realization of everything this country is capable of doing," O'Rourke said.In his Senate race against Cruz, O'Rourke often blurred their policy differences on issues like trade by saying the two agreed. And while O'Rourke took a series of progressive positions -- he argued for criminal justice revisions and marijuana legalization, backed "Medicare-for-all" and said he would support President Donald Trump's impeachment -- the race was primarily a clash of personalities.While O'Rourke will have to prove his policy bona fides, his strengths -- he's a tireless campaigner who won over younger voters -- will serve as a test of whether the Democratic base and its legions of young voters are more interested in inspirational figures or candidates whose ideology matches theirs.O'Rourke's entrance into the presidential race is the culmination of calls for him to explore a bid for national office that began after his closer-than-expected finish in the 2018 Senate campaign.Throughout that race, O'Rourke had insisted he would not run for president -- but that stance shifted after he lost. He acknowledged at a town hall shortly after the election that he was weighing a presidential bid. Then, in December, 4813

As computers, tablets and cellphones have become a growing part of our lives, the exposure to blue light emitted from these devices increases. While blue light exposure has been known to cause strain in eyes, Oregon State University researchers studied the effect of blue light exposure on aging. Based on to their findings, exposure to blue light could cause aging to accelerate. For their study, researchers used common fruit flies and exposed them to 12 hours of blue LED light and 12 hours of darkness. To compare, researchers kept a group of flies in total darkness, as well as a group of flies that were exposed to light that had the blue wavelengths filtered out. The researchers said they chose fruit flies because their cellular and developmental mechanisms are similar to humans.The researchers said that flies exposed to blue LED light sustained damage to their retinal cells and brain neurons and had impaired locomotion. Even more stunning, some of the flies, which exhibited some brain damage, were mutants that did not develop eyes."The fact that the light was accelerating aging in the flies was very surprising to us at first,” said Jaga Giebultowicz, a professor of integrative biology at Oregon State. “We’d measured expression of some genes in old flies, and found that stress-response, protective genes were expressed if flies were kept in light. "We hypothesized that light was regulating those genes. Then we started asking, 'what is it in the light that is harmful to them,' and we looked at the spectrum of light. It was very clear cut that although light without blue slightly shortened their lifespan, just blue light alone shortened their lifespan very dramatically.” 1708

Bank of America is raising its minimum pay to an hour for its more than 205,000 employees.The company will implement the new minimum wage over the next two years, according to comments made by CEO Brian Moynihan on MSNBC earlier Tuesday.Paychecks will initially be raised to an hour starting May 1, before climbing incrementally until 2021. Two years ago, the bank's employees got a raise to a minimum of an hour, according to a company press release.BofA is not the first main street bank to up minimum compensation for its employees. In January last year, JPMorgan Chase announced its intention to 624

As more states legalize marijuana, more law enforcement efforts are put in place to keep high drivers off the roadways.The State of Missouri is one that is cracking down on people driving after using pot. The Missouri Department of Transportation announced this week it will have a blitz on April 19-20.Those dates have been chosen because the number 420 is a code used by cannabis enthusiasts who celebrate the drug on April 20. In 2018, MoDOT reported 78 people were killed and 142 seriously injured in traffic crashes with at least one-drug impaired driver. 572

BALTIMORE — In states where medical marijuana is legal, researchers reported a reduction of pain and an increase in worked hours by residents older than 51 who use the alternative medicine, according to 215