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2025-05-31 19:44:54
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  日照颠痫病医师   

LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

  日照颠痫病医师   

JULIAN, Calif., (KGTV)— Firefighters in Julian are hoping to keep San Diego’s last volunteer fire department alive, despite being voted to shut down last week. The Julian Cuyamaca Fire Protection District is now suing the County, alleging the decision to dissolve the department was made in secret meetings. The court hearing for Wednesday was postponed in Downtown San Diego after a judge recused himself from the case.Two weeks ago, Debbie Mushet voted to have the county take over the Julian Cuyamaca Fire Protection District [JCFPD]. “I definitely voted yes for it, and I thought that was the end of it,” Mushet said. In this special election, 56% of Julian residents voted to have the San Diego County Fire overtake the historic volunteer department. “It’s worked as long as I’ve been up here, but it doesn’t work anymore. There’s a time when things just need to change,” Mushet said. “The volunteers have done a great job ion the past, but it’s just the money wasn’t going to be there.”Despite losing the special election and a unanimous vote by the Local Agency Formation Commission to officially dissolve the department, volunteer firemen are not ready to give up. Attorney Cory Briggs, who represents JCFPD said that decision was made through secret meetings. Therefore, the election results and the commission votes are “null and void.” When the County transition team came to the station on Monday, protestors staged a sit-in, refusing the leave the premises. JCFPD said in a statement, the County sent armed Sheriffs Deputies to “intimidate the unarmed JCFPD personnel who were peaceful truing to secure their facilities and equipment while the new lawsuit works its way through the courts.”“CalFire and the Julian Fire Department that exists now, I don’t understand why we can’t coexist,” Debbie Hickey said. “Every time it’s been really good response times. They knew right where to come.”For years, Hickey has relied on the Julian Fire Department for emergency care for her ill husband. She said she trusts the locals more than an outsider who would be assigned to cover the Julian area. “If I was to call 9-1-1, I don’t know who will come, I don’t know what the response time will be, and that’s a very scary situation to be in,” Hickey said. “My husband is staying down in the city during this time because quite frankly, I’m scared to death to let him come home to Julian.”A volunteer fireman told 10News off camera that since Monday they have not been allowed to respond to emergency incidents. In fact, they said their radios were disconnected. In the meantime, all 9-1-1 calls are being handled by Cal-Fire Station 50, down the street from the JCFPD station.While there is no official sit-in happening now, there are still many volunteers at the station. Volunteer crews have barricaded their engines inside the garage with their SUV’s, to try to stop the county from towing their vehicles. Either way, Mushet said this back and forth is getting out of control. “Let the vote speak for itself, let the count come in, volunteers step back, and it’s over and done,” Mushet said. “This is ridiculous. They asked for the vote they got their vote, and they were not happy with the decision, so they’re refusing to give in and it’s just sad. I’ve never seen this town so divided.”Wednesday’s court hearing scheduled for 8:30 a.m. was delayed after the assigned judge recused himself from the case. No reason was given for his recusal. The hearing was postponed until next Wednesday, April 17, 2019. 3522

  日照颠痫病医师   

JACKSONVILLE, Fla. — Multiple people are dead and injured after a fellow gamer fired about a dozen rounds in the middle of a tournament in Florida. A gaming expert says there was limited security.Gayle Dickie, CEO of Gamer World News, said these kinds of tournaments happen all over the world and all the time."This is horrifying, really," she said.The shots rang out on the second and final day of the Madden 19 Tournament. Players entered Chicago Pizza on the first floor of Jacksonville Landing and Dickie said there was little security."It's unfortunate because it was a smaller event, I mean it wasn't a large event," Dickie said. "If you go to events like the Barclay's Center or Staple's, you're going to go through a metal detector."Inside, gamers entered their own world."It is probably the biggest quality of a gamer, to have that intense focus, so everybody was focused on gameplay," Dickie said. She added that made it easy for 24-year-old David Katz to find his targets."It sounds like he knew who he was going after, so you know and you saw the two players sitting there. I saw the video and you can see them sitting there, and it didn't take him long, you know, obviously he knew what he was looking for," she said.Dickie said gamers can be as young as 12-years-old at these competitions."It's just shaken the core of the gamer community. No one would ever think that something like this would happen," she said.Dickie said the gaming world provides a place for everyone to find a niche community to which they belong. Now she hopes everyone watches out for one another."I think this will be the focal point of being aware of your surroundings no matter where you are," she said. 1747

  

JAMUL, Calif. (KGTV) - The Granite Lion Cellars in Jamul will break ground Wednesday on a new tasting room and wine cave, adding to their expanding vineyard and winery in the East County."We've been waiting for this for quite a while," says Tasting Room Manager Miriam Valdez. "I"m over the moon that it's finally happening."The multi-million dollar expansion will help Granite Lion deal with the increase of customers they've seen over the past year. Sommelier David Whited says they've gone from about ten visitors each week to 150.It's an excellent problem to have, and one that is spreading up and down Highway 94. There are now six wineries between Jamul and Campo, forming their own East County Wine Region.RELATED: New tasting room highlights wineries along Highway 94"You don't have to go all the way to Temecula or Escondido," says Whited. "You can do it here, 20 minutes from downtown."The new wine cave and tasting room are the latest sign that the region is gaining in popularity. The first tasting room in the area opened in 2014. Since then, wines along the 94 have won several awards and are starting to pull customers away from Temecula, Ramona and even Baja."As word gets out, people are coming here," says Whited."You arrive, and it's quiet," says Valdez. "It's away from the busy hustle and bustle of the city. You can enjoy nature. You can find a place here to rejuvenate and relax."The San Diego County Vinters Association says there are 116 wineries across the county. A recent report showed they have a million economic impact every year.Whited says the geography in the East County allows vineyards to grow more flavorful grapes commonly found in Europe."There are two mountain ranges that filter in the marine climate into the valley here which sets us apart from anywhere else in San Diego," he says.County Supervisor Diane Jacob is expected to attend Wednesday's event. Granite Lion says there's no time table for when construction on the new tasting room or wine cave will be complete. 2026

  

KANSAS CITY, Mo. — It's the happiest a Kansas City widower said he has been in three years."That's when our whole journey started," said Jim Purcell, who lost his 29-year-old wife Christy last year.Christy was diagnosed with brain cancer two months after their son, Jameson, was born.Scripps station KSHB in Kansas City reported earlier in April that Purcell's wedding rings had been stolen."It’s been a brutal journey. Every day was hard. When that ring was stolen, it was just another stab to the heart," said Purcell.Purcell shared the story on social media, explaining it was a devastating loss for him and his son."This was the one legacy item I wanted to pass on to him," said Purcell.Purcell's wallet was also stolen. The thieves used his credit card at the Walmart at 133rd and State Line; its surveillance video captured the alleged thieves’ faces.KCPD shared those images and together enough tips were gathered that detectives found the rings at a jewelry store in Raymore."They were honestly shocked," said Purcell.KCPD property crimes said it’s best to carefully photograph and document your items as extra insurance. Things like that can help them when trying to locate items.  "The police never gave up," explained Purcell, who said he was incredibly grateful people stepped forward with information. "A few of them actually put their own personal risk on the line."The group Stolen KC promotes people speaking up about theft daily."We’ve had people identified within five or 10 minutes," explained Todd Howerton, who is on the Facebook group's administration team.Members post photos of missing items with the idea that someone knows something. The group would like to grow to a strength of 200,000.  "The massive amount of people can facilitate finding things," said Howerton, who said they can take tips anonymously.That way, the things that are irreplaceable can be found."To have that, it gave me a lot of faith, a lot of hope, and a lot of thankfulness to people in the community who stepped up," said Purcell.Detectives told KSHB they are looking for three suspects in connection with the theft. They are wanted for possession of stolen property, burglary, and fraudulent use of credit.  2236

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