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Nearly 800 nurses were on a picket line Tuesday in Pennsylvania. The nurses work at St. Mary Medical Center in Langhorne, near Philadelphia, and they say they are walking off the job to fight for their patients.At issue is the hospital’s contract with the nurse’s union. The nurses want a new contract with higher wages and safeguards for patient safety.The nurses say they are caring for more patients during the coronavirus pandemic than they should, and that is putting patients at risk.“Safe staffing is the main issue in our negotiation--it's why we organized last year in the first place,” says Kathy McKamey R.N., who works on St Mary's MG2 unit and has been at the hospital for 10 years, said in a statement provided by the union.The hospital’s owner, Trinity Health, said the union rejected a contract last week that included higher wages.Hospitals in the Philadelphia area told the Philadelphia Inquirer that they would hire replacement nurses to work if the union goes on strike."We respect the union members’ right to strike, and we remain committed to negotiating in good faith to reach agreement on a fair, consistent and sustainable initial contract for St. Mary nurses. We look forward to the day productive negotiations can resume," said a statement from Trinity Health.The nurses say their strike will continue Wednesday if necessary. 1360

MINNEAPOLIS (AP) — A Minnesota judge has declined defense requests to move the trial of four Minneapolis police officers charged in George Floyd’s death, and also ruled that all four would be tried in a single proceeding.Hennepin County Judge Peter Cahill ruled Thursday after defense attorneys argued that pretrial publicity had made it impossible for the four men to get a fair trial.They had also cited a Sept. 11 hearing in which the men and their attorneys were confronted by angry protesters outside the courthouse.Moving the trial away from Minneapolis to less diverse areas of the state likely would have affected the makeup of the jury.The officers being charged are Derek Chauvin, J. Alexander Kueng, Thomas Lane and Tou Thao. Chauvin is charged with second-degree murder of Floyd, a black man who died after being restrained by him and the other Minneapolis police officers on May 25. Kueng, Lane and Thao have been charged with aiding and abetting Chauvin. 976

Moderna is asking American regulators to allow emergency use of its COVID-19 vaccine. It says its final results show the vaccine is 94% effective.The drug maker says it had 196 COVID-19 cases so far in its study. It says 185 of those participants received the placebo, while 11 got the real vaccine. The 30 people who became seriously ill in the trial didn't get the vaccine.FDA advisors are expected to look at all the evidence on December 17. They'll be checking out Pfizer’s vaccine on December 10.Pfizer and Moderna's success with their COVID-19 trials could impact how vaccines are made in the future.It has to do with how they work. They use what's called messenger RNA (mRNA) technology. The virus' genetic code is injected into the body so it can instruct cells on what antibodies to produce.It hasn't been approved to be used in a commercial vaccine before.“In the future, it's clearly going to be tough to beat RNA vaccines for speed and that's a wonderful thing. Just this demonstration of how incredibly fast they can move has been great. How effective they can be, I think will depend on a particular disease,” said Shane Crotty, Ph.D. with the La Jolla Institute for Immunology.Crotty says the narrowest application for this vaccine technology in the future is a similar situation where there's a new emerging virus."The mRNA vaccine has been tried for other infectious diseases and they have been investigated for cancer. There's a whole area of trying to vaccine against cancer, which has kind of been an elusive target,” said Dr. Alessandro Sette with the La Jolla Institute for Immunology.A big question with an mRNA vaccine is how long its protection will last. While there is encouraging findings, there's no historical comparison to look at.A big thing experts say has helped with a vaccine is there has been a lot of money put towards manufacturing before we even knew it would work.Click here to learn more about mRNA vaccines. 1958

NASHVILLE — Video shared on social media shows the moment an RV blew up on Christmas Day in Nashville, as investigators try to uncover a motive for the blast. 166

NASHVILLE, Tenn. — CBS News is reporting that a "person or persons" of interest has been identified in the bombing in downtown Nashville on Christmas morning. 166