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Right now, nearly 2 million people are living with limb loss in the United States. But new technology is bringing hope, with a prosthetic that responds to what a person is thinking. Whether it's picking out socks or picking up LEGO blocks, Mario Gasbarro seems to be doing it all just fine, using what his kids affectionately call his “robot arm.” “They seem to enjoy it more than my old arm,” Gasbarro jokes. At just 34 years old, Gasbarro’s doctors told him the lump that had been growing on his elbow was a malignant tumor. As it grew, his doctors determined amputation was his best option. “I don't need my left arm to be able to love my kids and love my wife and to be there for them, so that was always a priority,” Gasbarro says. Now, he’s living with this prosthesis, which moves based on how he thinks and moves his muscles. “I want to open my hand. I think, ‘OK, open my hand and move the muscles to open my hand,’ and I just need to replicate that muscle movement each time I want to try to open my hand,” Gasbarro says.Dr. David Schnur with Presbyterian/ St. Luke’s Medical Center worked with Gasbarro through the process. “Instead of the patient learning the prosthesis, the prosthesis really learns the patient,” Dr. Schnur describes of the prosthetic arm. Through a process called targeted muscle reinnervation, Dr. Schnur attached the nerves from Gasbarro’s forearm that power the hand to muscles in his elbow. “And then what happens is when Mario thinks about closing his hand, instead of causing a muscle to fire down his forearm, it causes a muscle to fire up in his in his biceps,” Dr. Schnur describes. Those signals are then picked up by his prothesis through pattern recognition. “He contracts the muscles. That makes sense for him to close the hand and the computer on the prostheses picks that up and is then able to convert that specific signal into a hand closed,” Dr. Schnur says. Gasbarro says it's not second nature just yet, but he's getting there with practice.“I’ve never felt limited, or like, I’m not able to do anything,” Gasbarro says. 2084

TAMPA, Florida — A sperm bank is promising to change its policy after WFTS television station uncovered one of its donors fathered more than 50 children across the U.S. and around the world — including some kids in the Tampa Bay area.Atlanta-based Xytex Cryo International did nothing illegal when it used the same donor to help birth at least 52 children. That’s because when it comes to sperm donations, U.S. regulations are few and there are no limits set by the government.Xytex wouldn’t speak on camera but told 529

SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Right now, doctors at the Centers for Disease Control and Prevention (CDC) are trying to figure out whether people who vape are at a higher risk for severe illness from COVID-19.Currently, vapers and smokers are not in the high-risk category. Doctors say coronavirus is a respiratory disease, which affects the lungs. People who vape or smoke already have weaker lungs. Last year, we saw many teens go to the hospital with lung illnesses associated with vaping.Dr. David Beuther, Chief Medical Information Officer at National Jewish Health says while vapers and smokers are at a greater risk, the risk of developing more severe complications is even greater. “I’d be more worried about you more than normal, but I think anybody that vapes, that inhales anything toxic into their lungs, is putting their lungs at risk, because it probably alters the immune system,” said Dr. Beuther. “It probably causes some irritation. It probably reduces your own lung’s ability to defend itself against this virus.Vaping may also contribute to more infections when people are using the device and exhaling.Dr. Beuther says while we try to stay six feet away from people, someone vaping may blow their cloud further than that and that could increase the risk of spreading the virus.Dr. Beuther encourages people to take this virus seriously and to consider quitting smoking. 1371

Stock trading was halted in the moments after the opening bell Monday as the Dow Jones Industrial Average opened down around 2,000 points amid coronavirus fears.It did not get any better on Monday. The Dow closed down 2,013 points at 23,851, marking the largest single-day drop in the market's history. The Dow has lost nearly 6,000 points from a high of 29,551 from just last month, which is nearly a 20 percent overall drop in the market's value.Trading was halted for 15 minutes in the moments after the opening bell, and trading resumed at about 9:50 a.m. ET. Following the trading halt, the Dow recovered somewhat before another mid-afternoon loss put it back 2,000 points on the day.The 2,000 point loss amounted to a 7.9 percent loss.According to 766