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WASHINGTON, June 7 (Xinhua) -- Advanced hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment, according to a new study published Tuesday in Gastroenterology, the official journal of the American Gastroenterological Association Institute.The study shows that patients who received peginterferon plus ribavirin treatment and who drank three or more cups of coffee per day were two times more likely to respond to treatment than non- drinkers.Among non-drinkers, 46 percent had an early virologic response; 26 percent had no detectable serum hepatitis C virus (HCV) ribonucleic acid at week 20; 22 percent had no detectable serum at week 48; and 11 percent had a sustained virologic response. In contrast, the corresponding proportions for those who drank three or more cups of coffee per day were 73 percent, 52 percent, 49 percent and 26 percent, respectively."Coffee intake has been associated with a lower level of liver enzymes, reduced progression of chronic liver disease and reduced incidence of liver cancer," said Neal Freedman, of the National Cancer Institute and lead author of this study. "Although we observed an independent association between coffee intake and virologic response to treatment, this association needs replication in other studies."Approximately 70 to 80 percent of individuals exposed to HCV become chronically infected. Worldwide, these individuals are estimated to number between 130 and 170 million. Higher coffee consumption has been associated with slower progression of pre- existing liver disease and lower risk of liver cancer. However, the relationship with response to anti-HCV treatment had not been previously evaluated.
SAN FRANCISCO, Sept. 13 (Xinhua) -- Researchers in San Francisco, U.S. have found in a latest study that bisphenol A (BPA) and methylparaben, two chemicals commonly used in consumer products, can interfere with the breast cancer drugs, local media reported on Tuesday.In the study, doctors from California Pacific Medical Center in San Francisco found that healthy breast cells from high-risk patients started to find ways to bypass breast cancer drugs after they were exposed to BPA and methylparaben in the lab.The cells exposed to the two chemicals kept growing and didn't die after they were introduced with Tamoxifen, a current standard drug therapy for female breast cancer and most common used treatment for male breast cancer, Dr. William Goodson, lead author of the study, told San Francisco Chronicle.Goodson said that BPA and methylparaben not only mimic estrogen 's ability to drive cancer, but appear to be even better than the natural hormone in bypassing the ability of drugs to treat it. The finds have been published online in the British medical journal Carcinogenesis.The research shows more evidence of safety issues of BPA, a chemical primarily used to make plastic baby bottles, food containers, household electronics and etc, as well as the less known methylparaben, a chemical preservative used in cosmetics and other personal care products.The researchers noted that the breast cancer rates have been growing by about the same amount in men as in women over the past three decades. Scientists have been looking at environmental causes for the disease and wondering where the hormones are coming from.Goodson said BPA and methylparaben are used so widely and even found in household dust, noting that it is still unknown whether the effects of exposure to the chemicals are reversible.Since 2008, several governments issued reports questioning the negative health effects of BPA, especially raising concerns regarding exposure of fetuses, infants and children. BPA use has been banned in baby bottles in a lot of countries and regions.As for methylparaben, the U.S. Food and Drug Administration said on its website that "at the present time there is no reason for consumers to be concerned about the uses of cosmetics containing parabens (including methylparaben)."
LOS ANGELES, July 5 (Xinhua) -- NASA's Juno spacecraft is 30 days away before its first launch window opens, the Jet Propulsion Laboratory (JPL) announced on Tuesday."One month from today, our first launch window opens at 11:34 a. m. EDT (8:34 a.m. PDT) and lasts 69 minutes," said Jan Chodas, Juno project manager from NASA's JPL in Pasadena, Los Angeles."Our primary launch period is 22 days long, and so if weather or other issues come up on Aug. 5, we have 21 more days to get Juno flying. Once we get Juno into space, it's a five-year cruise to Jupiter.""The launch window is the length of time allotted every day for an attempt to launch the spacecraft," said Chodas. "The launch period is the period of time in days when everything is in the right place to get your mission off to the right start."For a mission like Juno, getting everything in the right place includes considering the size of the rocket and spacecraft, where our home planet -- and in particular Juno's launch pad -- is pointed at any moment, and its location in space relative to other celestial objects like Juno's final target, Jupiter.Juno is scheduled to launch aboard a United Launch Alliance Atlas V rocket from pad 41-C at the Cape Canaveral Air Force Station, Florida.The solar-powered spacecraft will orbit Jupiter's poles 33 times to find out more about the gas giant's origins, structure, atmosphere and magnetosphere and investigate the existence of a solid planetary core.JPL manages the Juno mission for the principal investigator, Scott Bolton, of Southwest Research Institute in San Antonio.The Juno mission is part of the New Frontiers Program managed at NASA's Marshall Space Flight Center in Huntsville, Alaska. Lockheed Martin Space Systems, Denver, built the spacecraft.
Beijing, Sept. 6 (Xinhua) -- A sperm donation scandal disclosed recently has aroused growing concern in the United States.According to the New York Times' report, Ryan Kramer, the son of a donor, found that he has more than 150 half-siblings - they are all the children of the same donor."It's wild when we see them all together - they all look alike," said Cynthia Daily, mother of Kramer.As more women choose to have children on their own, the demand for sperm donors has surged.Some sperm banks are earning huge profits by allowing too many mothers to receive sperms from the same popular donors, according to the report.And this trend will lead to risks: rare genetic diseases could be spread more widely, and the children of the same donor could meet and, unbeknownst to them, commit incest, medical experts warned.Parents and donors are calling for a tighter regulation so that donor children can know more about their donors, and the number of kids from each donor can be limited.
WASHINGTON, June 15 (Xinhua) -- Using the deepest X-ray image ever taken, astronomers found the first direct evidence that massive black holes were common in the early universe, the U.S. National Aeronautics and Space Administration (NASA) said Wednesday in a statement.The discovery from NASA's Chandra X-ray Observatory shows that very young black holes grew more aggressively than previously thought, in tandem with the growth of their host galaxies.By pointing Chandra at a patch of sky for more than six weeks, astronomers obtained what is known as the Chandra Deep Field South (CDFS). When combined with very deep optical and infrared images from NASA's Hubble Space Telescope, the new Chandra data allowed astronomers to search for black holes in 200 distant galaxies, from when the universe was between about 800 million to 950 million years old."Until now, we had no idea what the black holes in these early galaxies were doing, or if they even existed," said Ezequiel Treister of the University of Hawaii, lead author of the study to appear Thursday in journal Nature. "Now we know they are there, and they are growing like gangbusters."The super-sized growth means that the black holes in the CDFS are less extreme versions of quasars -- very luminous, rare objects powered by material falling onto supermassive black holes. However, the sources in the CDFS are about a hundred times fainter and the black holes are about a thousand times less massive than the ones in quasars.The observations found that between 30 and 100 percent of the distant galaxies contain growing supermassive black holes. Extrapolating these results from the small observed field to the full sky, there are at least 30 million supermassive black holes in the early universe. This is a factor of 10,000 larger than the estimated number of quasars in the early universe."It appears we've found a whole new population of baby black holes," said co-author Kevin Schawinski of Yale University. "We think these babies will grow by a factor of about a hundred or a thousand, eventually becoming like the giant black holes we see today almost 13 billion years later."