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It's a black and white portrait photograph of John F. Kennedy. Underneath it, a handwritten message:"To Ambassador Estes -- With esteem and very warm regards, John F Kennedy."The document is believed to be the last thing President Kennedy signed in the Oval Office before he left on his fateful trip to Dallas.The photograph is now for sale at ,000, according to the Raab Collection, which is hosting the sale.The photo was signed on November 21, 1963 and was intended for Thomas Estes, the ambassador to Burkina Faso, who attended the final meeting President Kennedy held in the Oval Office.Estes recalled arriving at the White House on the morning of November 21 and playing with the President's son, John-John, while he awaited the meeting with the President.Estes entered the Oval Office and received the signed photograph. He then briefed the President on affairs in Burkina Faso.After the meeting ended, Kennedy left the Oval Office at 10:50 a.m. to helicopter over to Andrews Air Force Base.He would then fly to San Antonio, Texas.The next morning, in Dallas, he was assassinated. 1118

It's been several hours since Hurricane Laura made landfall, but the storm is still delivering devastating gusts of wind to inland Louisiana.In it's 4 a.m. CT update, the National Hurricane Center downgraded Laura from a Category 4 hurricane to a Category 3 hurricane. But the storm is still delivering maximum sustained winds of 120 mph, and "unsurvivable storm surge."According to the NHC, Laura will continue to deliver hurricane-force winds to central and northern Louisiana throughout the day on Thursday. The storm will then move to the northeast, bringing heavy rain to the Missouri Valley and Ohio Valley regions on Friday and through the weekend.Laura made landfall near Cameron, Louisiana at about 1 a.m. CT on Wednesday as an "extremely dangerous" Category 4 storm with 150 mph sustained winds. The Category 4 rating makes Laura is the strongest hurricane to make landfall in Louisiana in at least 60 years, according to the National Weather Service.The National Hurricane Center (NHC) said Wednesday that "Laura is expected to produce catastrophic impacts from the coast to well inland; life-threatening storm surge, extreme winds, torrential rain, flooding, and tornadoes."On early Thursday morning, NOAA's Coastal Inundation Dashboard showed storm surge warnings all across Louisiana's shoreline. The dashboard also noted that readings from Calcasieu Pass — a tributary near Cameron that flows into the Gulf of Mexico — showed that surge was recorded at about 9 feet as of 1:30 a.m. CT."Take the next few hours and get your family to a safe location," Louisiana Gov. John Bel Edwards said at a Wednesday afternoon press conference. He reminded residents that during a hurricane, it is hard to respond to emergency calls right away for people who decide to stay behind.The National Hurricane Center issued an "extreme wind warning" for areas of Southeast Texas and Southwest Louisiana at about 11 p.m. ET on Wednesday. A fairly new and rarely-used warning, it's issued for areas expected to see winds of 115 mph or higher. Residents in the affected areas are urged to find a low-lying interior room and protect their heads. 2145

Ireland has voted an emphatic "Yes" to amend the country's constitution to enable legislation that would allow women to have an abortion in a historic and emotionally charged referendum.With a high turnout of 64.13%, 1,429,98, or 66.4%, voted for the amendment Friday and 723,632, or 33.6%, against, according to the country's Referendum Commission. The results that were announced Saturday defied earlier projections that it would be a tight race.Only one county voted no -- the rural and religiously conservative Donegal in northwest Ireland.The vote signifies a resounding victory for the government of Leo Varadkar, the Prime Minister, or Taoiseach as the office is called in Ireland."Today is a historic day for Ireland," Varadkar said at a press conference. "A quiet revolution has taken place, and today is a great act of democracy.""A hundred years since women gained the right to vote, today we as a people have spoken," he said. "And we say that we trust women and respect women to make their own decisions and their own choices." He noted that people in "almost every county, almost every constituency, men and women, all social classes and almost all age groups" voted to repeal the amendment. "We are not a divided country," he said.Chants of "Yes we did" rose from the crowd as the Referendum Commission's Returning Officer Barry Ryan announced the final results.It was a scene of jubilation as some supporters burst into tears. Others began laughing as they hugged one another and asked each other, "Can you believe we did this?"Emma Gallagher, 22, began crying as she heard the final results."I feel safe now, I feel comfortable," she told CNN. "It felt for a long time women didn't matter. ... Now we know that we matter."Rene Wogan, 66, held Gallagher's hand and told her, "It was all for justice. You're forwarding the flag on for women."Thousands of people packed the square in front of Dublin Castle as abortion rights politicians, including Varadkar, also joined the celebration.He told Sky TV he expected legislation to be voted through by the end of the year."I feel enormous relief and great pride in the people of Ireland who didn't maybe know what they thought until they were finally asked the questions," Ailbhe Smyth, a longtime women's rights activist, told CNN."It has been a long and very hard road, but we never lost sight of this because it's so central to the existence, and the selfhood and personhood of women to have that control of our own bodies."The Eighth Amendment, which was added to the constitution following a referendum in 1983, banned abortion in Ireland unless there was a "real and substantial risk" to the mother's life.Repeal of the amendment has completed a circle of sweeping social reforms in the European Union nation that fly in the face of the traditional teachings of the Catholic Church, from contraception to divorce, and most recently same-sex marriage.Roscommon, in the rural interior, the only county to say no to same-sex marriage, also voted yes in the abortion referendum.Thousands of Irish working abroad returned to Ireland to cast their vote.Those opposed to abortion vowed Saturday to take their fight now to the Irish Parliament, where lawmakers will have to bring about legislation allowing for terminations in the first 12 weeks of pregnancy -- and later in cases where there is a risk to the mother's life or the fetus is not expected to survive.Dr. Ruth Cullen, spokeswoman for the anti-abortion LoveBoth campaign, conceded defeat Saturday before the count had finished."We will hold the Taoiseach to his promise that repeal would only lead to abortion in very restrictive circumstances. He gave his word on this, now he must deliver on it. No doubt many people voted for repeal based on the Taoiseach's promises in this regard," Cullen said at a press conference Saturday.The death of an Indian dentist ignited the abortion rights campaign in Ireland. Savita Halappanavar, 31, died in 2012 because of complications from a natural miscarriage after abortion was denied to her.Voters over 65 were the only age group overall not supporting the repeal of the amendment.Ireland's vote will likely put pressure on Northern Ireland to change its abortion laws, too. Despite Northern Ireland being part of the UK, the 1967 Abortion Act legalizing abortions never applied there, and even victims of rape and incest are forced to travel to mainland Britain if they want a termination.The-CNN-Wire 4478

It started out as a way to help her brother, and now, it's become so much more than that. Now one sister's efforts have made an impact far more than she could ever imagine.In their household, twins Sarah and Jacob Greichen are both included and involved. But one day after school a few years ago, Greichen realized outside the walls of their home, it was a different story."My brother got in and he was crying," Greichen said. "And he was saying, 'Mom I have no friends why don't I have any friends.'"Jacob has autism, and exclusion took its toll."He actually stopped talking completely," Greichen recalled. "He regressed, he went from probably a fourth, fifth, sixth-grade level to first-grade level and it was a really hard time for my family."Greichen decided to do something. And at 13 years old, she founded the non-profit Score A Friend, which builds clubs for students with and without intellectual disabilities in schools and communities."Every single kid meets friends through school or though activities and sports," Greichen said. "And Score A Friend is creating those opportunities for everyone. So that they can meet friends and then those friendships can go from school to home."Clubs can be focused on sports or electives, and one club even got the whole school involved with score a friend week."They talk about inclusion," Greichen said. "What unified sports are what person first language is what do you say when you walk up to a person with a disability and what is the right way to act."Now, Score A Friend has gone national, spreading to more than a dozen schools across the country, including at least two colleges."I mean now we have commercials and billboards out which is crazy!" Greichen exclaimed. "I mean, I never would have guessed this from the beginning."But for Greichen, her brother is the true measure of success."Jacob finally started talking again," Greichen said. "He started playing sports again he started talking to other students and he actually had people to sit with at lunch."Greichen sees Score A Friend becoming a movement. One inspired by the person closest to her, and impacting the whole world. 2151

International auction house Bonhams has canceled an upcoming sale of rhino products amid mounting pressure from environmental groups, it was announced Friday.The auction, which was due to take place in Hong Kong next week, would have featured more than 20 antiques carved from rhino horn, including a vase, a hairpin, a pouring vessel and a variety of drinking cups.In a statement provided to CNN, Bonhams global CEO Matthew Girling said: "(We recognize) there are widely held concerns about this issue and have decided that the sale of the rhinoceros carving scheduled to take place in Hong Kong on 27 November will now not take place."An online catalog for the sale, which had been titled "Exceptional Chinese Rhinoceros Horn Carvings from the Angela Chua Collection," has been removed from the auction house's website.Girling also announced that Bonhams would join the likes of Christie's in barring rhino horn items from its auctions."In future Bonhams will not offer artifacts made entirely or partly from rhinoceros horn in its salerooms," the statement said.The decision follows objections from high-profile conservation groups, including WildAid. An online petition, addressed directly to Girling, called the auction "unethical" and "unsustainable," suggesting that the sale would stimulate poaching.The petition, which had been signed almost 10,000 times at the time of writing, also claimed that the sale was "quite likely illegal," and composed of "horns from recently poached rhinos" rather than antiques.Girling refuted such suggestions in his statement, claiming that all rhino carvings that pass through the auction house are antiques with "known provenance" and requisite licenses."Bonhams stands behind the professionalism and expertise of its specialists," he added.The use of rhino horn in Chinese art and crafts dates back millennia. Carved cups, such as those featured in the Bonhams auction, were thought to protect their users from poisoning. It was once believed that rhino horn reacted with poison, producing a fizzing that would alert drinkers to danger.Despite global efforts to combat poaching, antique rhino horn items can still be bought and sold if they carry a license issued by CITES (Convention on International Trade in Endangered Species).Bonhams, which is headquartered in London, is considered among the world's oldest and largest fine art auction houses. Rhino products previously sold by Bonhams include a cup dating back to the 17th century, which sold for 4,000 earlier this year.Rhino horn items recently sold at the auction house's UK salerooms include a Buddhist carving from Nepal, which went for ￡40,000 (,000), and another elaborate Chinese cup worth ￡25,000 (,000). Other lots have included snuff bottles and walking sticks.A senior specialist for wildlife programs and policy at Humane Society International, Iris Ho, welcomed Friday's decision."We applaud Bonhams for canceling the November 27 auction of rhino carvings and warmly welcome its pledge of not offering any rhino horn artifacts in the future," she told CNN in an emailed statement."The price to do the right thing -- choosing saving rhinos over profiting from rhino horn sales -- is priceless. The responsibility of ensuring the survival of the remaining wild rhinos, less than 30,000 of them, rests upon all of us."Conservationists, including Humane Society International, also mounted pressure on auction house Sotheby's to withdraw rhino horn items from one of its upcoming sales.A two-day Chinese art auction, set to take place at Sotheby's Hong Kong next week, had featured three rhino horn items with a combined value of up to 420,000 Hong Kong dollars (,000), according to an online catalog.As of Saturday, Sotheby's announced it would withdraw the three rhino horn related lots from the sale in an e-mail statement. Chairman of Sotheby's Asia Nicholas Chow confirmed the auction house would no longer offer rhino artifacts in the future.The outcry comes less than a month after China announced that it was relaxing laws prohibiting the sale of rhino and tiger products for "medical" purposes. 4134

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