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SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087

SAN DIEGO (AP) — A pathologist testified Monday at a Navy SEAL's murder trial that a wounded Islamic State militant in Iraq could have died from a stabbing described by other witnesses.Dr. Frank Sheridan said he couldn't determine a cause of death because there was no body and a lack of other evidence.The testimony at the trial of Special Operations Chief Edward Gallagher, though, countered a statement offered last week by another SEAL who stunned the court when he confessed to the killing.Corey Scott testified Thursday that he killed the victim by plugging his breathing tube after Gallagher unexpectedly stabbed the fighter while treating him for injuries suffered in an air strike outside Mosul in 2017.Scott testified that the militant, described as an adolescent boy, would have survived the stabbing.But Scott said he decided to asphyxiate him because he assumed he would later be tortured and killed by Iraqi forces who captured him and brought him to the Navy medics for treatment.Gallagher, 40, is charged with murder in the killing of the boy and attempted murder for allegedly gunning down civilians from his sniper's post.He has pleaded not guilty and his lawyers blame his former troop mates for fabricating the accusations to get Gallagher ousted from the special forces because they didn't like his tough leadership.Scott and another SEAL said Gallagher had initiated medical treatment for the boy and then stabbed him one to three times in the neck for no apparent reason.Gallagher later texted a photo of the corpse to friends with the following message: "Good story behind this, got him with my hunting knife."His lawyers said the message was an attempt at dark humor.Sheridan based his testimony on witness accounts and video of the wounded war prisoner before the alleged knifing.After the boy was wounded in an air strike — more than an hour before he was brought to the U.S. forces for treatment — he was interviewed by an Iraqi TV news crew. He appeared lucid and did not have significant hemorrhaging, Sheridan said."He's clearly responsive," Sheridan said. "There's no sign he's bleeding from any wound."Witnesses at the scene said Gallagher treated the boy for a leg wound and an apparent collapsed lung. The patient was sedated and given a breathing tube for a wound they believe occurred from the air strike blast.He was breathing normally after the procedure when Gallagher suddenly pulled out his personal knife and stabbed him in or near the neck, witnesses said.Depending on the location of the stab wounds, he could have died from profuse internal or external bleeding, Sheridan said. But he couldn't make that determination."I can't give an opinion on the cause of death," Sheridan said. "There just isn't enough evidence."___Melley reported from Los Angeles. 2807

SACRAMENTO, Calif. (KGTV) — The California Medical Board is looking into a case where a San Diego doctor is accused of using dirty needles on pediatric patients. Newly released documents by the California Medical board states Dr. Bret Robert Gerber used dirty syringes on a 2-year-old and a 10-year-old in July 2016. At the time, Dr. Gerber worked at Scripps Coastal Medical Center in Hillcrest. The documents state a medical assistant reported seeing the doctor bring in two boxes of unauthorized needles from home. Upon closer review, she noticed that the syringes had expired in 2008, and the boxes contained dead insects and what looked to be rodent droppings. Three years before this alleged incident, Dr. Gerber was arrested by Mono County Sheriff's deputies for having psychedelic mushrooms, cocaine, and ecstasy. Deputies found the drugs inside his Winnebago during a traffic stop as the doctor was on his way to the Burning Man Festival. He later admitted to using ecstasy at the festival.Instead of court, Dr. Gerber went through a diversion program and the Medical Board put him on probation. However, in March 2018, documents showed Gerber violated his probation after failing to provide a bodily fluids sample for a drug test. Despite his prior offenses, Dr. Gerber’s medical license was never revoked. Dr. Gerber continues to practice pediatric medicine twice a week, most recently at Mid-City Community Clinic in City Heights. 10News contacted the California Medical Board for comment. Officials said Dr. Gerber now faces multiple charges including gross negligence, repeated negligent acts, failure to maintain accurate medical records, and unprofessional conduct. 1688

SAN DIEGO (CNS) - A 32-year-old man is expected to survive a stab wound to the abdomen after being attacked by a suspect who rode up on a bicycle and assaulted him on a bridge in the Hillcrest community of San Diego, police said.The victim was with friends on a bridge in the 3900 block of Vermont Street when the bicyclist rode up about 9 p.m. Saturday and stabbed him once in the abdomen, said Officer Robert Heims of the San Diego Police Department.The suspect rode away southbound on the bridge. Paramedics rushed the 32-year-old man to an area hospital with non-life-threatening injuries.No description of the suspect was available. San Diego police urged anyone with information regarding the assault to call them at 888-580-8477. 744

SAN DIEGO — San Diegans can participate in AstraZeneca's COVID-19 vaccine trial, which recently showed 90 percent effectiveness under a certain dosage.AstraZeneca announced Monday that its vaccine was 90 percent effective when participants started with a half dose, followed by a full dose at least four weeks later. It is currently seeking participants through UC San Diego Health and other partners for its ongoing trials. Full doses given four weeks apart were 62 percent effective in the trial. “These findings show that we have an effective vaccine that will save many lives," said Professor Andrew Pollard, Chief Investigator of the Oxford Vaccine Trial, in a statement released by AstraZeneca. "Excitingly, we’ve found that one of our dosing regimens may be around 90 percent effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply."Elana Godebu, a UC San Diego urologist, said she has seen the impacts of Coronavirus firsthand. She is currently practicing at El Centro Regional Medical Center, affiliated with UC San Diego. She says the center is filling up because of a rise in local cases and patients coming up from Mexico. The state recently built a 50-bed tent in the parking lot for non-Covid patients. Godebu got the first dose of the vaccine two weeks ago, which also could have been a placebo."Personally I've seen my friends and my colleagues and my patients, they've gotten sick, they've lost family, they've lost friends, and so we got the AstraZenica trial out in El Centro," she said. Godebu said she encourages anyone who has an opportunity to get the vaccine to take advantage. "If we try to get to herd immunity the other way we're going to lose so many people," she said. AstraZenica is the latest drugmaker to report strong efficacy. Earlier this month, Pfizer and Moderna said their trials were 95 percent effective. AstraZenica says its vaccine could separate from the others because it can be transported, handled and stored at regular refrigerated temperatures and administered in regular health care settings. 2099

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