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WASHINGTON, Dec. 12 (Xinhua) -- British scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. The findings, published Monday in the U.S. journal Cancer Cell, reveal how cancer cells grow faster by producing their own blood vessels.Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF -- the target for the anti-cancer drug Avastin. Making these proteins requires the slotting together of different parts of genes, a process called splicing.Scientists at the University of West England and the University of Bristol discovered that mutations in one specific cancer gene can control how splicing is balanced, allowing a master switch in the cell to be turned on. This master switch of splicing makes cancer cells grow faster, and blood vessels to grow more quickly, as they alter how VEGFs are put together.In experimental models, the researchers found that by using new drugs that block this master switch they prevented blood vessel growth and stopped the growth of cancers."The research clearly demonstrates that it may be possible to block tumor growth by targeting and manipulating alternative splicing in patients, adding to the increasingly wide armory of potential anti-cancer therapies," the authors said.
BEIJING, Dec. 12 (Xinhuanet) -- For many multinational firms, the past 10 years in China have not only marked the rise of the world's second-largest economy but have also been a decade of expansion and profit growth.As they look back at this "golden decade", which is often used to describe the days after China entered the World Trade Organization (WTO) in 2001, their early expectations and ambitions in a more liberalized Chinese market were found to be more than fulfilled.When German auto giant BMW set foot on the Chinese mainland by establishing its first office in Beijing in 1994, its products were still far too luxurious for ordinary Chinese.In 2001, only 6,500 vehicles were sold under the BMW and Mini brands in China.NYK Diana, a container ship, anchors at Qingdao Port in East China's Shandong province on Thursday, as workers load cargo.But sales started to pick up with China's WTO entry, when the removal of trade barriers brought unprecedented economic growth and a booming market.In 2010, the vehicle maker, which started a joint venture with the domestic Brilliance China Automotive in 2003, sold 169,000 vehicles in China.That record is set to be broken this year as more than 170,000 cars were sold only in the first three quarters."We are both beneficiaries and firm supporters of the open market system," said Christoph Stark, president and CEO of BMW's Greater China region.By liberalizing its market, China, which celebrated the 10th anniversary of its WTO accession on Sunday, has become a thriving market and a savior for foreign enterprises hit hard by the global downturn.In 2009, when General Motors declared bankruptcy in the United States amid the global recession, its Chinese branch saw sales rise 66.9 percent year-on-year to more than 1.8 million units.In 2010, China overtook the United States to become GM's largest national market.The list of similar companies is extensive, as China's decade-long membership of the WTO has helped the Asian powerhouse attract 347,000 foreign firms with investment of more than 0 billion in the past 10 years.Chong Quan, deputy representative for China's international trade talks, said foreign enterprises made more than 0 billion in profit in the 10-year period, with an average annual increase of 30 percent."The accession to the WTO has made China a more transparent, safe and predictable market, as well as an essential part of the global economy," said Dominique Poulique, president of Alstom China.The French power engineering and train company, with more than 30 entities and about 10,000 employees in China, is one of the major foreign suppliers to the Chinese rail transport market."Rapid changes took place in China in the past decade, with its massive investment in infrastructure construction and notable development in energy," Poulique said.Wang Zhile, director of the research center of transnational cooperation under the Ministry of Commerce, said increasing shared interests between China and multinationals are putting them into an inseparable community, one that has found win-win solutions in the past decade.There is also high-quality labor at a relatively low cost, including white-collar workers, he added.Admittedly, the huge market and rich resources have powered up multinational firms in global competition, especially during and after the financial crisis.Forty-nine percent of the responding multinational companies had higher expectations for China in the wake of the global financial crisis in 2008 and 2009, according to a recent survey by the Economist Intelligence Unit, a business information arm of the Economist Group.Although showing signs of a slowdown, China's economy is still widely expected to grow by more than 8 percent next year, at a time when debt and financial instability are weakening growth in other leading economies.Poulique said he expected China's rapid growth to continue into the next decade, especially in the infrastructure construction market."For Alstom, the top task here is to keep adapting to the changing business environment," he said.Many foreign companies are moving research and development facilities to China in the hopes of making it a base for talent and technology.In Shanghai, 347 multinationals have set up regional headquarters, with the establishment of 333 foreign-funded research and development centers.
SEOUL, Jan. 6 (Xinhua) -- LG Electronics, the world's No.2 TV maker, said Friday that it will showcase a smart TV that runs Google TV during next week's Consumer Electronics Show (CES) in Las Vegas.The LG-made Google TV powered by Google's Android operating system (OS) will be unveiled next Monday at the U.S. consumer electronics fair in Las Vegas, according to an e-mailed statement by LG.The Internet TV will offer its Android-based user interface, enabling consumers to enjoy web browsing and social networking, LG said. Multi-taking will also be available as the Internet surfing, social networking and TV functions can be run simultaneously.LG's three-dimensional (3D) technology will be available through its Google TV. With a single click of a remote controller, any two-dimensional (2D) program or movie can be viewed in 3D due to the built-in 2D to 3D conversion engine."Through Google TV, LG has merged Google's established Android operating system with LG's proven 3D and Smart TV technologies, offering consumers a new and enthralling TV experience," said Havis Kwon, chief executive of LG Electronics' home entertainment business.
BEIJING, Jan. 25 (Xinhua) -- China's railway authorities said Wednesday that it would put 315 more trains into service on Wednesday to cope with Lunar New Year travel demand, compared with 159 on Tuesday.About 3.7 million passengers hit the rails on Tuesday, up from 2.29 million on Monday, the Ministry of Railways said in a statement on its website.The ministry expected a post-festival travel peak on Friday.The country's trains carried a total of 83.46 million passengers from Jan. 8 to 22, up 7.9 percent from a year earlier, the ministry said in a statement issued on Tuesday.The 40-day Spring Festival travel season kicked off on Jan. 8 this year, with hundreds of millions of people, mainly migrant workers and college students, heading home for the most important festival in China.A total of 3.16 billion passenger trips are expected during the year's travel rush, up 9.1 percent from a year earlier. Of those journeys, 235 million are likely to be made by train, up 6.1 percent year-on-year.The Spring Festival, or Chinese Lunar New Year, falls on Jan. 23 this year.
BEIJING, Oct. 14 (Xinhuanet) -- Materialism could be harmful to marriage, according to a new study published in the American Journal of Couple & Relationship Therapy Thursday.The researchers collected online "relationship assessment" questionnaires from 1,734 U.S. married couples.The questionnaire covered the topics about the couples' marital satisfaction, conflict patterns, marital communication, and marriage stability, and so on.Non-materialistic couples were about 10 to 15 percent better than those materialistics in their marital satisfaction, marriage stability and conflict levels, according to the study."What we found was a general pattern that materialism seems to be harmful to marriage," said study researcher Jason Carroll, a professor of family life at Brigham Young University.It didn't matter whether the materialistic spouse was the man or the woman, he added.However, materialism is not simply black-or-white: some couples can pursue their fortune and keep their relationship strong at the same time, the researcher suggested.But breaking their materialistic thought would be helpful for most couples, Carroll concluded.