吉林包皮手术可以用医保吗(吉林纳米包皮环切手术全过程) (今日更新中)

Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine.  1210

In a typical year, most people want to see family for the holidays. But many people don’t really want to stay with family.So if you’ve already made the decision to spend the holidays this year with family members outside of your household, here’s one perhaps welcome byproduct of 2020: Instead of sleeping in your childhood bedroom or on the basement futon, you might finally stay in a hotel.While 95% of Americans say it’s usually important to spend the holidays with family, 30% say they believe they would enjoy the holiday season more if their family came together without all sleeping under the same roof. That’s according to an online survey of 2,000 U.S. adults by SWNS Media Group and commissioned by Motel 6, done in 2019 — before COVID-19 was part of the vernacular.Now you have reason to be optimistic about an otherwise brutal 2020 — you finally have a tough-to-argue-with excuse to not stay with family (or not to let family stay with you, if you’re usually the host). Instead, if you’re still planning to see family, it’s more likely that this is the year you find yourself staying at a hotel or vacation rental.Here’s why you should take advantage of this one silver lining in what most people agree has been a crummy year for traveling and seeing family.You’ll have better quality timeTwenty percent of respondents in SWNS Media Group’s 2019 survey said getting on each other’s nerves was a top concern when it comes to staying with family during the holidays. Another 20% cited family drama. More time together means more opportunities to get annoyed and allow tense topics to creep up: the election, the pandemic, the economy, healthcare … and the list goes on.According to the Centers for Disease Control COVID-19 guidelines, gatherings that last longer pose more risk than shorter gatherings. So instead of a long weekend with family, this year you might meet up for a few hours to have Thanksgiving dinner at a park, or to go on a neighborhood walk to view the Christmas lights.Just a few hours together before heading back to your hotel allows you to focus on easier conversation topics without causing a ruckus. That’s enough time to discuss the latest happenings in Zoom school or to chat about your newfound hobbies, without getting into areas that are more likely to ruffle feathers.You’ll sleep more comfortablyStaying with family as an adult can be uncomfortable — literally. Maybe you and your kids are shoved in a basement. A loose piece of plywood from the futon is jamming into your back. Your kids are in sleeping bags on the floor in the hallway, blocking your path to the bathroom (which you’re sharing with your sibling and their own family).This year, go for the hotel or vacation rental. You’ll have a real bed. The kids might get their own room, and you won’t have to share a bathroom with anyone outside of your household.You’ll also get to live on your own schedule. So turn on the TV in the morning without worrying about your host’s dog barking at it. Or stay out as long as you want, without grandma worrying that you’re out too late (even though you’re a full-grown adult).You have a good excuse not to host guestsIf you’re usually the host, you already know it’s a lot of work. But this year, you’ve got a built-in excuse to avoid those extra loads of laundry and dishes. No making sure you have enough vegan, gluten-free and keto food options in your pantry to accommodate all of your guests.Instead, you have an opportunity to see family members in your city without them living inside your house. This year, you might recommend the family meet up for apple-picking (the CDC lists visiting orchards where people use hand sanitizer before picking apples as only a moderate-risk activity).Even if you’re still serving as the host in some capacity — perhaps offering up your backyard for an outdoor feast — you’re off the hook for one of the worst aspects of being a host: ensuring everyone has a bed to sleep in for the night. Nearly 40% of hosts said organizing sleeping arrangements is one of the most stressful parts of preparing for guests, according to the SWNS Media Group survey.You won’t offend your host by not staying with themWhile some folks find aspects of hosting incredibly stressful, some guests find it just as stress-inducing to decline invitations from hosts who insist you sleep over. Some of the world’s top etiquette experts have devoted effort into devising ways to politely-but-firmly decline invitations from hosts who are adamant that you stay over.Bu this year, you don’t need an etiquette expert to help you explain why you’d rather opt for a hotel.You’ll find better hotel deals this yearIf you’ve always toyed with the idea of staying at a hotel but staying with family usually wins out in the name of saving money, here’s another reason to give in to the hotel for the 2020 holidays: You’ll likely score better rates than in any other year.With summer travel down, hotel chains offered up some pretty good deals, many of which are still valid now — and many hotels offered up bonus points in their loyalty programs with every stay. At one point, Best Western was handing out gift cards just for staying with them.Luxury travelers can still take advantage of a super sweet deal in Fairmont’s nearly unbeatable buy one, get one free offer for every night’s stay until April 30, 2021 (book before Nov. 16, 2020).If travel doesn’t pick up, it’s likely you’ll find more deals ahead of the winter holiday season. In fact, Hyatt has already announced that all World of Hyatt members will earn 3x points for qualifying stays through January 4, 2021, for up to 150,000 bonus points (anyone can become a member for free online).And if you’re a Hilton Honors member, you’ll earn double bonus points for stays at Hilton hotel between now and December 31, 2020. That’s good for building up your hoard of Hilton Honors points, but it’s also great if you’re trying to earn Hilton Honors elite status, as you’ll also earn double night credits for your stay.The bottom lineThis year has been rough in a lot of ways, but it’s also provided opportunities for silver linings. Travelers have already experienced some positive changes, like waived airline change fees, improved hotel cancellation policies and better airplane sanitization (because when were the tray tables ever cleaned before this?).And this holiday season, there’s one more reason to look on the bright side: Whether you’re masking it up for Christmas this year or hosting a socially distanced in-person Thanksgiving picnic, you’re finally off the hook for sleeping on the squeaky futon in the basement. Perhaps the best present you can give yourself this holiday season (without feeling guilty about it): your own hotel room.More From NerdWalletWhen Should You Book Basic Economy?Travel Insurance Options for Digital NomadsHow Safe Is Air Travel Right Now?Sally French is a writer at NerdWallet. Email: sfrench@nerdwallet.com. Twitter: @SAFmedia. 6979

If you’re shopping for a car, you may already know that buying used is a smart move that greatly expands your choices. The key is knowing where to look for them.Buying a used car will not only save you money but also allow you to shop higher-end brands, says Ivan Drury, Edmunds.com’s senior manager of insights. For example, maybe you wanted a new Toyota Camry. Instead, he says, you can save about ,000 and get a 3-year-old Lexus.Because of the bankruptcy of Hertz rental car agency, along with the many cars coming off lease, there are a lot of used vehicles to choose from, says Jeff Huang, who attends auctions as the remarketing sales supervisor at Westlake Financial Services. “A good used car is a real value proposition — and there are definitely deals to be had,” Huang says.Shoppers looking for great bargains will find them in cars older than 7 years, says Mark Holthoff, used car editor at Klipnik, a website for used car enthusiasts. “That’s because the depreciation curve has mostly been flattened,” he says. For example, a 2014 Mercedes-Benz E-Class sedan, costing ,000 new, now sells for about ,000.Shop in the right placeNew cars are sold only by franchised dealers, but used cars can be purchased from a variety of sellers:Used car departments at new-car dealerships.Used car superstores such as CarMax.Online used car sellers such as Carvana, Shift and Vroom.Car rental sales lots.Independent used car lots.Private parties.Public auctions.You’ll typically find the newest and more expensive models at new-car dealers’ used-car lots, the only place to turn if you want a certified car with a warranty and factory financing. Prices are likely to be higher than other lots’ but negotiable.National used-car chains such as CarMax, online retailers and rental car agencies also offer newer cars, often with factory warranty remaining. You can also get a loan and buy extended warranties. Prices are typically no-haggle.Independent lots, private parties and public auctions typically deal in older or cheaper cars. The upside is that you may find a 20-year-old one-owner cream puff, cheap. It does happen. But most cars have had several previous owners, and a checkered past is not rare. Plus, you’ll have to arrange your own financing.Adjust your expectationsThere is a built-in risk-versus-reward element to used car shopping: The more you’re willing to spend, the less chance the car will need repairs and overdue maintenance. Here’s an overview of the three price levels of used cars:High-end used cars: If your budget is over, say, ,000, you might consider getting a certified pre-owned (CPO) car from a dealer. Shopping for a CPO car is easier because it’s pre-inspected and comes with an included warranty. While you’ll have to pay a premium, you’ll also be able to buy a car with more modern technology and safety features. Of course, you can always buy a non-CPO car and purchase an extended warranty.Midrange used cars: A sweet spot for used car buying is a 3-year-old vehicle coming off a lease. Many of these cars will sell for 40% of their original price and still retain a new-car feel, according to Drury. Another source of near-new bargain-priced vehicles is car rental lots. According to an iSeeCars analysis, Hertz vehicles are selling for an average of ,389 below market value.Older used cars: Many people are afraid that cars from 7 to 15 years old will require costly repairs. But Holthoff points out that new cars can effectively cost the owner ,000 a month in depreciation.“You might have to spend money on a repair, but depreciation is a constant,” he says.To offset repairs, set aside 0 a month so sudden mechanic bills won’t deplete your savings.It’s best to buy older cars from private-party sellers because you can get a better idea of the mechanical condition, Holthoff advises. A used car dealer will show you the vehicle history report, but a private party might have the service records and can answer many other questions.Look for unexpected valueThe used car market is vast and, if you can spot an outlier, you can save big money. Here are a few examples of how to find that diamond in the rough:Cars that haven’t been recently redesigned will sell for less. Check car sites such as Edmunds.com to find out when the last time major changes were made to a model.While there is a stigma to buying a used rental car, the vehicles are well-maintained and priced lower than buying from dealers, Drury says.If a car dealer’s vehicle history report shows you are looking at a former rental car, leave and buy a similar one directly from the rental agency’s sales lot. You’re likely to find it cheaper.Be willing to travel to an area where the car you want is less popular. For example, all-wheel-drive vehicles sell for less in the southern U.S., where winter driving isn’t a factor.Be willing to travel to a more competitive market. A Honda dealer with a city to itself has less pressure to dicker on a CPO vehicle than a dealer in a city with three or four rivals.Used luxury cars often offer the biggest savings, according to Holthoff. The money you save on the purchase can be used if any repairs are needed.More From NerdWalletDon’t Fall for COVID-19 Student Loan Relief ScamsGet Your Finances Ready to Refi Student Loans5 Reasons It’s Smart to Lease a Car Right NowPhilip Reed is a writer at NerdWallet. Email: articles@nerdwallet.com. Twitter: @AutoReed. 5428

In a defiant pair of CNN interviews, former Trump campaign aide Sam Nunberg said Monday he refuses to comply with a grand jury subpoena in the Russia investigation."Screw that," Nunberg told CNN's Gloria Borger. "Why do I have to go? Why? For what?"And in a separate interview with CNN's Jake Tapper, Nunberg said he blamed the investigation's existence on President Donald Trump's firing of James Comey as FBI director -- including an interview where Trump said he was thinking about the Russia investigation when he fired Comey and the fact that he held a meeting with top Russian officials in the Oval Office.  646

House Republicans are unveiling key details and the text behind their tax legislation Thursday, but not without some reservations from rank-and-file members.In advance of the bill's release -- which will be called the "Tax Cuts and Jobs Act," according to a source in a meeting with GOP members Thursday -- a source shared a summary of the plan, which permanently lowers the lowers the corporate tax rate to 20% and limits the home interest deduction to loans up to 0,000.The bill will also increase the standard deduction for individuals and households, repeals the alternative minimum tax and increased the child tax credit to ,600. The House GOP bill will also finally repeal the estate tax in 2024.Members will see the tax framework Thursday morning when the House ways and means committee releases its bill that is expected to expand the child tax credit, repeal the estate tax, lower the corporate tax rate and reduce the number of individual tax brackets from seven to four.But there are still key questions about what will be in the bill and whether the leadership can wrangle the votes they will need to deliver President Donald Trump a major legislative victory by the end of the year. 1208

来源：资阳报