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concerned about weaker economic growth being a reality for most advanced economies."Further mis-steps from European and US policymakers risk converting the cracks in their economies into a much deeper global system crisis which would have worrying economic and?social consequences," he warned.But Smith, whose bank is focusing on Asia to drive profit growth, remains optimistic for the outlook in the Asia-Pacific region.He said that the fact is that Australia is incredibly well positioned because of the nation's linkage to Asia, which remains the best performing part of the global economy.His comments came after ANZ reported a 1.45 billion U.S. dollars underlying profit for the June quarter, up 1.3 percent compared to the March quarter.
WELLINGTON, June 7 (Xinhua) -- Scientists in New Zealand have developed a new drug to fight previously untreatable hypoxic cancer tumors, which form in areas of the body starved of oxygen.The researchers at the Auckland University have entered an agreement for the clinical development of CEN-209, which was developed over 10 years of research, said a statement from the university Tuesday.CEN-209 was designed to enhance the effectiveness of radiotherapy and chemotherapy in solid hypoxic tumors, which were resistant to standard cancer therapies, said the statement. In lung cancer patients for example, about half of tumors had hypoxic regions.The new drug worked by damaging the DNA of hypoxic cancer cells, while leaving normal, healthy tissues alone.CEN-209 was designed and created by researchers at the university's Auckland Cancer Society Research Centre (ACSRC), using computer models of drug transport within tumors to accurately predict the anti-tumor activity of the drugs."Our computer models of drug transport developed in-house allowed the synthetic chemists to test their design theories and considerably shortened the discovery process," said Associate Professor Michael Hay, who led the ACSRC research chemists."CEN-209 improves markedly on previous agents in this class in terms of its ability to penetrate tumors, and this is reflected by its improved activity in the laboratory, when combined with long or short courses of radiotherapy," said researcher Professor Bill Wilson.Under the agreement between the university's Auckland UniServices Ltd. and California-based Centella Therapeutics, Inc., a subsidiary of Varian Medical Systems, Inc., Centella will have exclusive rights to CEN-209, which it will develop and trial with Cancer Research UK.The work on CEN-209 is the culmination of a program initiated with funding from the U.S. National Cancer Institute, and more recently from the Maurice Wilkins Centre for Biodiscovery. Ongoing preclinical research on CEN-209 and a backup compound was funded by grants from the Auckland Medical Research Foundation, Genesis Oncology Trust and Health Research Council of New Zealand, said the statement.

BEIJING, July 1 (Xinhuanet) -- China must adopt a holistic approach to addressing food safety challenges connected to the risk of contracting infectious diseases from contact with animals, the World Health Organization (WHO) has said. Peter Ben Embarek, food safety officer at WHO's China office, said the country faces risks connected to the need to produce more meat, eggs and milk to feed its growing population. He said the increased production will ramp up the risk of people being infected by food-borne diseases because of poor slaughtering oversight and the absence of proper surveillance and inspection systems. About 50 percent of pigs in China are slaughtered outside of formal facilities without the inspection of veterinarians or food safety officers. He said poorly trained producers have little or no awareness of food safety or the risk of animal diseases being passed on to humans. Such an environment could lead to the emergence of a new pandemic of influenza. During the past 60 years, 30 percent of the 335 new infectious diseases worldwide were transmitted through food, he said. Yet in many parts of China, public awareness remains low about such things. Xu Aixiang, a 35-year-old resident of Rizhao city in Shandong province, prefers to buy live poultry at local markets. Like many of her neighbors, she takes the chickens she buys home to slaughter them. "I get fresher chickens that are better quality this way," she said. "When vendors sell slaughtered chickens, the meat is no longer fresh and may have had water injected into it to make it heavier." But Ben Embarek cautioned that such live-animal markets are high-risk places for the exchange of viruses and diseases between animals and humans. He said simple and cost-effective measures can be taken to improve such markets' hygiene standards, such as the installation of separate areas to keep live poultry away from customers as well as improving air flow and waste management. Several UN agencies, including the WHO and the Food and Agriculture Organization, called on China to adopt an integrated approach to preventing emerging epidemic diseases and maintaining ecosystem integrity at an event themed "One Health" that convened on Wednesday in Beijing. At the gathering, representatives from the Ministry of Health, the Ministry of Agriculture and the Chinese Center for Disease Control and Prevention shared experiences from efforts to mitigate the H5N1 and H1N1 influenza outbreaks in China and said they were committed to working together in the future. Su Jingliang, an associate professor of preventive veterinary medicine at China Agricultural University, said his lab had detected the outbreak of a new type of flavivirus in ducks that led to a significant fall in egg production at farms in Beijing as well as in Hebei, Jiangxi and Shandong provinces. The pandemic was brought under control in March. No cases of humans contracting the disease have been reported so far but Su said he was concerned about the possibility of farmers becoming infected through close contact and long exposure to sick ducks. He said precautionary measures should be taken in cooperation with the Ministry of Health and other government agencies and checks should be run on people who are at high risk. Xu Wei contributed to this story.
SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.
SINGAPORE, July 3 (Xinhua) -- The over 60 nursing homes in Singapore, especially those run by voluntary welfare organizations, are facing a bed crunch, local daily Straits Times reported on Sunday.The newspaper found in a check with 20 homes that more than half of the nursing homes were running at full or almost full capacity. Homes run by voluntary welfare organizations, where there are subsidized beds, have long waiting lists.The average waiting time for a bed in nursing homes run by voluntary welfare organizations rose from 50 days in 2008 to about 60 days early last year, the newspaper said.It is easier to get a bed in a privately run home, though only slightly and if you can afford it. Econ Healthcare Group, which runs eight nursing homes in Singapore, said the occupancy rate is 99 percent and it has waiting lists of up to 20 people at some branches.Demand for nursing homes in the city state can only grow given the aging population. By 2030, the number of people aged 65 or above is projected to reach 900,000, or one in every five residents.
来源:资阳报