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The Food and Drug Administration resisted pressure from the Trump administration on Tuesday by releasing a set of guidelines that could push an emergency use authorization of a coronavirus vaccine past Election Day.The FDA’s new guidance notes that an Oct. 22 meeting of its Vaccines and Related Biological Products Advisory Committee will not be to discuss specific vaccine candidates. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit."Being open and clear about the circumstances under which the issuance of an emergency use authorization for a COVID-19 vaccine would be appropriate is critical to building public confidence and ensuring the use of COVID-19 vaccines once available,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said. The FDA's new guidance on emergency use authorization of COVID-19 vaccines underscores that commitment by further outlining the process and recommended scientific data and information that would support an emergency use authorization decision.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved."Trump previously said he would consider overruling the FDA on its vaccine guidelines in hopes of speeding up the process. There is both health and economic pressure for a vaccine to be developed as the coronavirus continues to claim an average of 800 US lives a day, according to Johns Hopkins University data. The number of deaths per day related to the coronavirus is expected to increase as the weather gets colder, according to the University of Washington’s Institute for Health Metrics and Evaluation.On Tuesday, House Speaker Nancy Pelosi blasted the Trump administration for involving itself in the vaccine approval process.“Trust in the vaccine is key to the acceptance of the American people, which is essential to crushing the virus.“The White House’s decision to reject FDA medical experts’ minimum safety and efficacy standards for emergency use authorization of a vaccine is an extremely dangerous act. We are all praying for a safe and effective vaccine as soon as possible, but the damage of the Trump Administration rushing a vaccine before it is known to be safe and effective could be catastrophic."Dr. Anthony Fauci told CNN's Chris Cuomo on Monday that he expects a vaccine candidate to be given an emergency use authorization by the end of 2020. "By the time we get to November, December, maybe earlier, I don't think it's going to be earlier, but it's still possible," Fauci said. "It will be early, but I think comfortably around November or December we'll know whether or not the vaccine is safe and effective. I actually am cautiously optimistic from what I've seen about preliminary data in phase one, that there's a very good chance we'll have a safe and effective vaccine." 3256
The family of Stephon Clark, the 22-year-old black man shot and killed by Sacramento Police, will be exploring "every legal remedy possible" in search of justice, according to their attorney Benjamin Crump.Speaking to CNN on Sunday, Crump said Clark's death should not be "swept under the rug." Crump also called for accountability from both sides."There's great mistrust" between communities of color and police, Crump told CNN's Dan Simon. The attorney has also represented the families of Trayvon Martin, Michael Brown and Tamir Rice. 545
The E.W. Scripps Company is a partner with The Associated Press and has been following guidance from their election desk on 2020 race updates.From Wednesday through Saturday, Joe Biden had a projected total of 264 Electoral College votes, six shy of the number needed to become president. As Election Day ground on into “election week,” it became increasingly clear that Biden would oust President Donald Trump from the White House. The question, rather, was where he would win, when it would happen and by how much, as late counted ballots in Nevada, Pennsylvania and Georgia continued to keep Biden in the lead and offered him multiple paths to victory. On Saturday, Biden captured the presidency when The Associated Press declared him the victor in his native Pennsylvania at 11:25 a.m. EST, garnering the state’s 20 electoral votes, which pushed him over the 270 electoral vote threshold needed to win. 914
The Force is with the Hollywood Walk of Fame.Legendary actor Mark Hamill will be honored Thursday with the 2,630th star on Tinsel Town's iconic sidewalk. Hamill's "Star Wars" co-star Harrison Ford and director George Lucas will help unveil the star during the ceremony.Of course, in addition to his role in the "Star Wars" saga, the California native has encompassed all aspects of the entertainment world, including Broadway, voice-over roles, and television.The ceremony can be viewed live online:Fans will undoubtedly recognize Hamill's memorable turn as "The Joker" throughout various Batman shows, movies, and media. He's also played notable roles in the films "Corvette Summer," "The Big Red One," "Slipstream," "Kingsman: The Secret Service" and the upcoming "Brisby Bear."On Broadway, Hamill flexed his acting reach in productions of "The Elephant Man," "Amadeus," "The Nerd," and "Six Dance Lessons in Six Weeks."Hamill had some fun with TV host Jimmy Kimmel Wednesday on "Jimmy Kimmel: Live," where he cleared a little room from his place on the Walk of Fame."Well, I just picked out my spot for the star. I'm getting it ready for tomorrow," Hamill, with a jackhammer in hand, tells Kimmel before the camera pans down to reveal Kimmel's own star demolished. "Hey Jimmy I got an idea, why don't you put your star in front of Hooters?"However, Hamill's work extends past entertainment. The actor has been involved with charitable work with NAI (USC Neighborhood Academic Initiative), the Make-A-Wish Foundation, and Feeding America. 1579
The Clark County School District is using the field at Boulder City High School as the basis of design on upcoming bids for artificial turf projects. That design utilizes an organic infill consisting of a mixture of cork and sand. Any materials submitted as part of bids will be reviewed by the appropriate design professional retained by CCSD for the project.Additionally, CCSD’s decision to move away from crumb rubber infill was solely a response to the heat generated by this type of infill. Organic infills have proven to create a much cooler playing surface. 573