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COEBURN, Va. — When nurses Teresa Tyson and Paula Hill pull their RV into the small towns of Appalachia, they bring a warmth that's part of the charm of these mountains. They also bring help that's become scarce in this part of the country. “It’s kind of like we’re the forgotten people," Hill says. "Not only are we vulnerable but we’re forgotten and lot of people feel like they do not matter.”“The cancer rates here in the central Appalachia region are just so high for so many diseases," Tyson adds. The two natives of this rural part of Virginia run 572

Days after returning home from a Punta Cana vacation, Marie Trainer called out of work with a backache and nausea. Then her temperature spiked and dropped, sending her to a local Stark County, Ohio, emergency room in the early hours of May 11.When Trainer woke in a hospital bed nine days later, her hands and legs had been amputated.It took doctors seven days to discover Trainer incurred a severe infection, not from a "tropical" travel disease as they first suspected, but from her German shepherd's kisses.Trainer contracted a rare infection from the bacteria capnocytophaga canimorsus, probably when her German shepherd puppy, Taylor, licked an open cut.Dr. Margaret Kobe, the medical director of infectious disease at Aultman Hospital in Canton, Ohio, treated Trainer and described her as "delirious" when she entered the intensive care unit. Shortly after, she became unconscious. Her skin started changing rapidly to a purplish-red color, and then it progressed into gangrene. Trainer then developed a blood clot."It was difficult to identify, We're kind of the detectives. We went through all these diagnoses until we could narrow things down," Kobe said.The infection spread to the tip of her nose, ears, legs and face. "She didn't lose parts of her face. But her extremities is what she had to have surgery on," Kobe said.The family sought a second opinion, hoping to save Trainer's limbs. But doctors said the damage had already been done. Blood tests and cultures confirmed the diagnosis of capnocytophaga."That was a pretty hard pill for us to all swallow, to say she was fine a couple days ago on vacation and now she's actively getting worse by the minute and now her hands and feet aren't alive, like this doesn't happen, it's 2019," said Gina Premier, Trainer's step-daughter and a nurse at Aultman Hospital.Trainer has had eight surgeries so far and is working with doctors to be fitted for prostheses."This is off the scale, one of the worst cases we have seen in terms of how ill people become with infections," Kobe said. "She was close to death."A rare cause of illness in humansMarie Trainer says she knows her German shepherd puppy licked a slightly infected scratch. When the bacteria spread to humans, they do so through bites, scratches or other close contact with dogs and cats, according to the 2336

DETROIT — For more than four decades, Chuckie O’Brien has been known as a key suspect in Jimmy Hoffa’s disappearance. Now, the 139

DERRY, N.H. — A New Hampshire town waited 50 years to open a time capsule, only to find the big surprise was ... nothing.Derry's time capsule was sealed in 1969, and for as long as Cara Potter has served as director of the Derry Public Library, the capsule has sat on the same shelf."Nobody touched it until last spring," Potter 346

Defense Secretary Mark Esper explicitly says he's seen no hard evidence that four American embassies had been under possible threat when President Donald Trump authorized the targeting of Iran’s top commander. Esper's comments in Sunday television interviews raises questions about the scale of the threat described by Trump last week. As the administration struggled with its justification for the drone strike that killed Gen. Qassem Soleimani, Esper and members of Trump's national security team are trying to refocus attention on voices of dissent inside Iran. 577