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LOS ANGELES, April 6 (Xinhua) -- Freeze-dried strawberries may play a role in the prevention of esophageal cancer, a new study suggests."Strawberries may be an alternative or work together with other chemopreventive drugs for the prevention of esophageal cancer," said lead researcher Tong Chen, M.D., Ph.D., assistant professor, division of medical oncology, department of internal medicine at the Ohio State University.Study findings were presented at the ongoing 102nd annual meeting of the American Association for Cancer Research (AACR) in Orlando, Florida, according to the American Association for the Advancement of Science (AAAS) on Wednesday."We concluded from this study that six months of eating strawberries is safe and easy to consume. In addition, our preliminary data suggests that strawberries can decrease histological grade of precancerous lesions and reduce cancer- related molecular events," said Chen, who is also a member of the Molecular Carcinogenesis and Chemoprevention Program in the Ohio State University Comprehensive Cancer Center.The study involved a group of participants who consumed 60 grams of freeze-dried strawberries daily for six months and completed a dietary diary chronicling their strawberry consumption.The researchers obtained biopsy specimens before and after strawberry consumption. The results showed that 29 out of 36 participants experienced a decrease in histological grade of the precancerous lesions during the study.Using freeze-dried strawberries was important because by removing the water from the berries, they concentrated the preventive substances by nearly 10-fold, Chen said.Esophageal cancer is the third most common gastrointestinal cancer and the sixth most frequent cause of cancer death in the world, she noted.Chen and her team are studying esophageal squamous cell carcinoma (SCC) which makes up 95 percent of cases of esophageal cancer worldwide. China, where this study took place, has the highest incidence of esophageal SCC, according to the AAAS.In a previous study, Chen and colleagues found that freeze- dried strawberries significantly inhibited tumor development in the esophagus of rats. Based on these results, they embarked on a Phase Ib trial that included participants with esophageal precancerous lesions who were at high risk for esophageal cancer."Our study is important because it shows that strawberries may slow the progression of precancerous lesion in the esophagus," Chen said.But she said they need to test this in randomized placebo- controlled trials in the future.
WASHINGTON, March 24 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Thursday approved the use of Zostavax, a live attenuated virus vaccine, for the prevention of shingles in individuals 50 to 59 years of age. Zostavax is already approved for use in individuals 60 years of age and older.In the United States shingles affects approximately 200,000 healthy people between the ages of 50 and 59, per year. It is a disease caused by the varicella-zoster virus, which is a virus in the herpes family and the same virus that causes chickenpox.After an attack of chickenpox, the virus lies dormant in certain nerves in the body. For reasons that are not fully understood, the virus can reappear in the form of shingles, more commonly in people with weakened immune systems and with aging."The likelihood of shingles increases with age. The availability of Zostavax to a younger age group provides an additional opportunity to prevent this often painful and debilitating disease" said Karen Midthun, director of FDA's Center for Biologics Evaluation and Research, in a statement. ( Shingles is characterized by a rash of blisters, which generally develop in a band on one side of the body and can cause severe pain that may last for weeks, and in some people, for months or years after the episode.Approval was based on a multicenter study conducted in the United States and four other countries in approximately 22,000 people who were 50-59 years of age. Half received Zostavax and half received a placebo. Study participants were then monitored for at least one year to see if they developed shingles. Compared with placebo, Zostavax reduced the risk of developing shingles by approximately 70 percent.The most common side effects observed in the study were redness, pain and swelling at the site of injection, and headache, according to the FDA.Zostavax, manufactured by Merck & Co., was originally approved on May 26, 2006, for the prevention of shingles in individuals 60 years of age and older.

LOS ANGELES, April 4 (Xinhua) -- A woman's breast milk cells may be used to predict cancer in future research, according to a study published by HealthDay News on Monday.In the study, researchers at the University of Massachusetts in Amherst collected breast milk from 271 women in the United States. All had either undergone a biopsy of the breast to check for cancer, or were scheduled for one.The researchers evaluated breast milk samples from the biopsied and non-biopsied breasts.The researchers first isolated potentially cancerous cells, known as epithelial cells, and then isolated DNA to look for signals that regulate tumor suppresser genes.In the next step, the researchers analyzed three genes among the many known to undergo a process called methylation in breast cancer. Methylation in a specific region of a gene can inhibit or suppress the expression of a gene.For one gene, SFRP1, the average methylation was higher in the biopsied breast, the study found.Among the women whose biopsies detected cancer, average methylation of the RASSF1 gene in the biopsied breast was considerably higher compared to the non-biopsied breast.Among the women whose biopsies detected cancer, average methylation of the RASSF1 gene in the biopsied breast was considerably higher compared to the non-biopsied breast."It looks as if we can use the cells from breast milk to assess breast cancer risk," said Dr. Kathleen Arcaro, an associate professor of veterinary and animal sciences at the university.It's too soon, however, to assess the cancer detection rate associated with breast milk cell examination, she said."We can't say at this point for two reasons," she said. "One is, we need long-term follow-up. And the second really important reason is, we need to sample a larger panel of genes."Arcaro is to present her findings later Monday at the annual meeting of the American Association for Cancer Research in Orlando, Florida, according to HealthDay News.
BEIJING, Feb. 11 (Xinhua) -- China plans to dig 1,350 wells in eight major wheat-growing provinces to help ease the ongoing drought that is threatening the country's grain harvest, said the Ministry of Land and Resources (MLR) on Friday.The ministry will establish an anti-drought and well drilling operation headquarters and three front working teams in north China, Huanghuai area - along the Yellow and Huai rivers - and northwest China, said the MLR at a video conference.Also, China Geological Survey, an institution directly under the MLR, will transfer experienced technicians from its nine affiliated units to form three emergency squads and 12 emergency groups to assist local governments in finding water in those regions, said the MLR.Further, the MLR will send geological survey teams from its nine affiliated units and eight provinces, including Sichuan, Yunnan and Guizhou, to the eight provinces, it said.The survey teams will bring 100 sets of advanced geophysical prospecting instruments and 320 sets of drill machines to dig 1,350 wells to ease the water shortages affecting people and livestock, especially those in mountainous areas, and strengthen local irrigation, it noted.The eight provinces include Shandong, Henan, Hubei, Anhui, Shanxi, Shaanxi, Gansu and Jiangsu, which are China's major wheat-producing regions and have been severely affected by months-long drought.The MLR had previously put in place a series of measures to relieve drought and find water, such as making underground water layout maps and sending experts to drought-hit regions to give technical guidance, said the MLR.As of 3 p.m. Thursday, the drought had affected 101.28 million mu (6.75 million hectares) of crops nationwide and left 2.81 million people and 2.57 million livestock short of drinking water, said the Office of State Flood Control and Drought Relief Headquarters.
BEIJING, Jan. 30 (Xinhua) -- China hoped Egypt could restore social stability and normal order at an early date, Foreign Ministry spokesman Hong Lei said Sunday."China has been closely watching the development of the situation in Egypt," Hong said when asked to comment on the ongoing turmoil in the country."Egypt is a friendly country with China, and we hope Egypt could restore social stability and normal order at an early date," he said.
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