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Jamal Khashoggi's fiancée implored President Donald Trump and first lady Melania Trump "to help shed light on" his disappearance in an op-ed published by The Washington Post on Tuesday evening.Khashoggi, a prominent Saudi journalist, vanished October 2 after entering the Saudi consulate in Istanbul. As a columnist for the Post, Khashoggi was a frequent critic of the Saudi regime.On Saturday, Turkish officials told the Post that Khashoggi had been killed at the Saudi consulate. CNN has not been able to independently confirm these reports, and the Saudi government has denied them.Khashoggi was at the consulate to obtain paperwork so he could marry his Turkish fiancée, Hatice Cengiz.Cengiz writes in the Post op-ed, "I implore President Trump and first lady Melania Trump to help shed light on Jamal's disappearance."Trump said Monday that he was "concerned" about reports of Khashoggi's disappearance.Cengiz wrote in the op-ed that Khashoggi had gone to the Saudi consulate in Istanbul "despite being somewhat concerned that he could be in danger." He had no warrant for his arrest in Saudi Arabia and didn't think that the tensions between himself and the Saudi royal family were at a dangerous level."In other words, he did not mind walking into the Saudi Consulate in Istanbul because he did not believe that something bad could happen on Turkish soil," Cengiz wrote. "It would be a violation of international law to harm, arrest or detain people at a diplomatic mission, he said, and noted that no such thing had ever happened in Turkey's history."After three hours of waiting, Cengiz was told that Khashoggi had already left but she says "there's no proof that he came out.""Although my hope slowly fades away each passing day," Cengiz writes, "I remain confident that Jamal is still alive."Trump had spoken about Khashoggi's disappearance briefly with reporters on Monday."I don't like hearing about it, and hopefully that will sort itself out. Right now, nobody knows anything about it," he said."There's some pretty bad stories about it," Trump added. "I do not like it."Cengiz urged Saudi Arabia, "especially King Salman and Crown Prince Mohammed bin Salman, to show the same level of sensitivity and release CCTV footage from the consulate."Turkish President Recep Tayyip Erdogan has called on Saudi Arabia to release surveillance footage to prove that Khashoggi left the consulate."Although this incident could potentially fuel a political crisis between the two nations, let us not lose sight of the human aspect of what happened," Cengiz writes."Jamal is a valuable person, an exemplary thinker and a courageous man who has been fighting for his principles. I don't know how I can keep living if he was abducted or killed in Turkey." 2766

LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871

LA JOLLA, Calif. (KGTV) - A famous architectural gem known as the Razor House is for sale for ,000,000 in La Jolla.The home, which is named for Razor Point, was designed by leading architect Wallace E. Cunningham. Located in La Jolla Farms near the Torrey Pines Golf Course, the home sits on some 12,000 square feet of cliff-top land.PHOTOS: Tour the 'Razor House' in La Jolla“Few residences are so groundbreaking in design that they need a name to convey their architectural significance. The Razor House is one of these rare and celebrated masterpieces which has a name that pays homage to a stunning yet treacherous landscape where majestic cliffs meet the infinity of the ocean,” said Laleh Monshizadeh. “When The Razor House was completed in 2007, the property was widely regarded as an architectural marvel. The cinematic nature of its design has made it a highly sought-after filming location and has already been featured in TV commercials for Calvin Klein and Visa Black Card.”Designed with concrete, stainless steel and glass, the space takes advantage of panoramic ocean views.“Walled in by sheets of glass, the house is so transparent that you feel as if you are suspended in air, completely surrounded by water,” said Niloo Monshizadeh. “It takes a daring visionary to take a modestly sized, steep oceanfront lot that had been previously declared ‘unbuildable’ and create a masterpiece nestled sensitively into the hillside. Following the Wrightian tradition of organic architecture, Wallace E. Cunningham drew inspiration from the challenging terrain, imagining a dynamic residence spread across the land that takes advantage of its position amid deep canyon, golden sandstone and jagged bluff leading into vast views of the Pacific Ocean.”The home is listed by Laleh and Niloo Monshizadeh of Coldwell Banker Residential Brokerage in La Jolla.9826 La Jolla Farms Rd.Bedrooms: 4Baths: 4Partial baths: 2Square feet: 10,653 in main house, 1,301 in guest house 1986

Kaaboo is live in Del Mar all day! Live music, art, culture from this 3 day live festival! Powered by @LiveListOrganizers announced the music festival's lineup on Twitter, with acts including the Red Hot Chili Peppers, Pink, Tom Petty and the Heartbreakers, Muse, Weezer, and Jane's Addiction.  307

Kentucky's statewide primary is Tuesday, and those wanting to vote in person could be in for a long wait. Louisville and Lexington, the state's two largest cities, each have only one in-person polling location.The state's primary was postponed more than a month because of the coronavirus pandemic, and elections officials allowed all voters to vote by mail using absentee ballots. They have also cut down the list of in-person voting locations to just 170 statewide. According to the Kentucky secretary of state, they typically have around 3,700 polling locations. The changes have prompted responses from politicians, celebrities and activists who accuse the state of voter suppression. 697