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DETROIT — WXYZ received disturbing new undercover video showing dogs at an animal testing lab in Michigan.The Humane Society of the United States says the footage shows dogs getting doses of pesticides and drugs. According to the group, its investigation found beagles and hounds suffering and dying.The video was supposedly shot at the Charles River Lab in Mattawan, Michigan, between April and August 2018.Experiments were carried out on behalf of three companies, including Dow Chemical, which is based in Midland, Michigan, according to the Humane Society.The organization is demanding that the testing stop and the dogs be released.The Dow Chemical company responded to the report Tuesday. The company said it is required to test pesticides and fungicides on dogs to make sure they aren't too toxic.The HSUS investigation at the Charles River Lab found some dogs had their jaws surgically broken to test dental implants. Others had drug pumps inserted beneath their skin.Currently, the focus is on 36 beagles being force-fed toxic chemicals sometimes up to four times a day for almost a year."We need to get out of this cycle of using dogs just because we have always used them," said Kathleen Conlee, vice president of animal research issues at the Humane Society of the United States.HSUS investigators went undercover at Charles River Lab for nearly 100 days in spring and summer of 2018."I don't think everyone in there is an uncaring person. I've been there myself but hopefully someday they will see the light and join us in trying to end abuse of animals like this," Conlee said.Companies pay the lab to carry out their product testing on animals. That includes Michigan-based Dow Chemical. The company contracted the lab to use 36 beagles for a year-long test on the toxicity of a new fungicide. The program started in summer 2018 and will be completed in July 2019."These dogs were getting force-fed pesticides every day for a one-year long pesticide test that is widely considered unnecessary. These animals are still alive today but will be killed in July," said Conlee.U.S. law only requires a 90-day test to get new pesticides approved. However, Dow said that Brazil requires a year of testing, hence the long test underway in Michigan.HSUS said that's not the only way dogs suffer at Charles River Lab. Its undercover operatives said dogs had their chest cavities opened up to see how that area tolerated having drugs pumped in. Others had invasive surgeries to test an amyotrophic lateral sclerosis, or ALS, drug. The Humane Society said the long-term results don't justify the cruelty."Over 90 percent of drugs that show promising results in animals ultimately fail in humans. We want to see better tests that are relevant to humans," Conlee said.Dow's full statement on the testing can be read below: 2865

Drugmaker Bristol-Myers Squibb announced Thursday a billion deal to buy Celgene, in one of the biggest mergers in pharmaceutical industry history.The deal, which still needs the approval of shareholders and regulators, will be paid with a combination of stock and cash. Bristol-Myers is the result of a 1989 merger of two companies that traced their roots back to the 19th century, and is the eighth largest US drugmaker, with annual revenue of .8 billion in 2017. Celgene is the ninth largest with revenue of billion.The combined company could become the fourth largest pharmaceutical company in the United States.Shares of Bristol-Myers ( 663

Ernest "Fritz" Hollings, the former senator from South Carolina, has died, according to a statement from his three children."Our father, Fritz Hollings, was dedicated to his family, the United States Senate and the people of South Carolina. He was a hero for us and millions of Americans. He was so honored to have served the people of this great state in the South Carolina House of Representatives, as lieutenant governor and governor, and as a member of the United States Senate," said his children, Michael Hollings, Helen Hollings Reardon and Ernest Hollings III, in a statement. "While we are heartbroken, we hope that in the coming days and weeks as we celebrate our father's life, all South Carolinians will be reminded of his service to our state and nation."Andy Brack, a spokesman for Hollings, told CNN the former senator died early Saturday morning of natural causes.Hollings, 97, was a stalwart of South Carolina politics for many decades serving both as governor of the state beginning in 1958 as well as 38 years as a US senator starting in 1966.He is credited with creating the National Oceanic and Atmospheric Administration, making port security stronger and helping to revamp airport security following the September 11 terrorist attacks. He was one of the authors of the Gramm-Rudman-Hollings Act, which sought to cap federal spending, but its passage was not successful.The Democrat was well-known for his colorful language with a deep Southern accent and distinctive silver hair. He made a brief run for the Democratic presidential nomination in 1984, but quickly bowed out. 1609

CEDAR RAPIDS, Iowa — Court records say an Iowa man made a woman watch the miniseries “Roots" and told her it would make her better understand her racism. Robert Noye is charged in Cedar Rapids with harassment and false imprisonment, 245

Disgraced movie mogul Harvey Weinstein is back at Bellvue Hospital Wednesday evening, just hours after being sentenced to 23 years in prison on rape and criminal sex act charges, a spokesperson confirmed to PIX11 News. "He was having chest pains and the Rikers staff decided for safety to send him back to Bellevue now," the statement said. "He will be evaluated and likely will stay overnight. We appreciate the care and concern of the Department of Corrections officers and staff."This is the second time Weinstein 529

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