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WASHINGTON, May 11 (Xinhua) -- Johns Hopkins University researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.The work, published Wednesday in the journal Science Translational Medicine, suggests that liver cells derived from so- called "induced-pluripotent stem cells (iPSCs)" could one day be used as an alternative to liver transplant in patients with serious liver diseases, bypassing long waiting lists for organs and concerns about immune system rejection of donated tissue."Our findings provide a foundation for producing functional liver cells for patients who suffer liver diseases and are in need of transplantation," says Yoon-Young Jang, assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "iPSC-derived liver cells not only can be generated in large amounts, but also can be tailored to each patient, preventing immune-rejection problems associated with liver transplants from unmatched donors or embryonic stem cells." A microsopic view shows human embryonic stem cells in various stages of differentiation into liver cells in this photo taken at Stanford University and released by the California Institute for Regenerative Medicine, March 9, 2009iPSCs are made from adult cells that have been genetically reprogrammed to revert to an embryonic stem cell-like state, with the ability to transform into different cell types. Human iPSCs can be generated from various tissues, including skin, blood and liver cells.Although the liver can regenerate in the body, end-stage liver failure caused by diseases like cirrhosis and cancers eventually destroy the liver's regenerative ability, Jang says. Currently, the only option for those patients is to receive a liver organ or liver cell transplant, a supply problem given the severe shortage of donor liver tissue for transplantation. In addition, mature liver cells and adult liver stem cells are difficult to isolate or grow in the laboratory, she says. By contrast, iPSCs can be made from a tiny amount of many kinds of tissue; and the embryonic stem- like iPSCs can grow in laboratory cultures indefinitely.For the study, Jang and colleagues generated human iPSCs from a variety of adult human cells, including liver cells, fibroblasts ( connective tissue cells), bone marrow stem cells and skin cells. They found that though the iPSCs overall were molecularly similar to each other and to embryonic stem cells, they retained a distinct molecular "signature" inherited from the cell of origin.

FUZHOU, Feb. 5 (Xinhua) -- A minibus rolled over and fell into a reservoir in Shaowu City in southeast China's Fujian Province Friday afternoon, killing 10, local officials said early Saturday morning.Nine people were rescued, and two were still missing.The minibus bound for Shaowu from Yong'an lost control at 5:27 p.m. Friday when the driver apparently tried to avoid a motorbike. It fell into the Qianling Hydropower Station reservoir, according to officials with Nanping city government.About 200 police and rescuers were still looking for the missing people, and the investigation into the accident is underway.

SAN FRANCISCO, April 18 (Xinhua) -- Apple Inc. has sued Samsung Electronics Co. over patent infringement in a latest suit, U.S. media reported Monday.The suit, filed last Friday in U.S. District Court in Northern California, alleged that Samsung's smartphones, such as "Glaxy S 4G" and "Nexus S," and the Galaxy line of tablet computers violated Apple's patent and trademark, according to All Things Digital, a technology and startup company news site."It's no coincidence that Samsung's latest products look a lot like the iPhone and iPad, from the shape of the hardware to the user interface and even the packaging," the report quoted an Apple representative as saying.Intellectual property suits can be often seen among mobile computing rivals, including suits between Microsoft and Motorola, a suit by Oracle against Google, and Apple's patent dispute with Nokia and HTC.Although Samsung supplies chips for a number of Apple products, Apple CEO Steve Jobs once openly mocked Samsung and other tablet makers as "copycats" during the iPad2 launch. Last month, Apple is reportedly partnering with China's Taiwan Semiconductor Manufacturing Co. to make iPad chips.

WELLINGTON, May 22 (Xinhua) -- One in every eight women giving birth in a New Zealand hospital last year was Asian, local media reported Sunday.In the country's most populous city, Auckland, 5,149 Asian women gave birth, more than double the number of 15 years ago, the New Zealand Herald reported.Last year was the first year in the city when more Asian women gave birth than indigenous Maori women, who registered 5,015 births.Citing figures from the government statistics agency, Statistics New Zealand, the report said the majority of women nationwide who gave birth last year were still of European descent, accounting for 43,965 of last year's 63,897 births.But more women of other ethnic backgrounds were also becoming mothers, including those from the Middle East, Latin America and Africa.Auckland University head of obstetrics and gynaecology, Professor Lesley McCowan, said the increase reflected New Zealand is an increasingly multicultural society.

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