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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394
For pets, the skies of United Airlines lately have not been so friendly.It's not just the French bulldog that died on a Houston-to-New York flight Monday after a United flight attendant told its owners to put the dog in an overhead bin.Data from the US Department of Transportation show that three times as many animals died on United flights last year than on all the other US carriers put together. As you can see from this chart, 2017 wasn't an exception.United has had the highest rate of pet deaths of any US airline for the past three years.In fairness, the airline in recent years has also been the largest transporter of animals -- mostly dogs and cats, but also more exotic pets such as birds and geckos. Also, according to the DOT report for 2017, several of the animals had pre-existing health issues such as heart disease. (The report did not specify how many animals were flown in the cargo hold as opposed to the plane's cabin.)But even when accounting for their larger volume of animal passengers, United still leads all other airlines in rate of deaths per 10,000 pets.United did not respond to multiple requests for comment for this story. But spokesman Charlie Hobart told CNN on Tuesday that the airline is investigating the French bulldog's death "to prevent this from ever happening again."As for the 2017 report, he said, "The overwhelming majority of the incidents were attributed to animals not being acclimated to its crate or the animal having a pre-existing condition we weren't aware of. Any time there is an incident with animals we do a thorough review." 1612
For more than three decades, the Catholic Church has been rocked by sex abuse scandals spanning the globe.And for decades, the church has been accused of protecting itself rather than the victims of child sexual abuse.Here are some major scandals and revelations involving the Catholic Church and allegations of abuse. 326
Food insecurity has skyrocketed in communities across the country during the pandemic. Rural communities have been hit especially hard. In Louisiana, which the highest-ranked state for food insecurity for children and the fourth-ranked state in food insecurity for seniors, food banks are becoming more important than ever before.For grandmother Mary O'Neal, she's raising her 8-year-old grandson on her own. Without help from her local food bank, she said she doesn't know how they would get by.Her husband passed away a couple of years ago, which cut their fixed income in half. Since then, O'Neal said she's really had to save."I had to pick up, and we had to start doing things different," said O'Neal. That loss was made worse when a tornado ripped through their northeast Louisiana home."I said, 'You know, Lord, you’ve sent me through the biggest storm of my life. This is just another storm. You brought me through the other one, and you’re going to bring me through this one,'" she said.But O'Neal said she never imagined the storm coronavirus would bring right into her kitchen. Food was running short—not only for her, but for her diabetic grandson, so she visited The Care and Hope Ministry, a small church turned community food bank, for some help."For us, it’s more than just than a box of food," said Pam Walker, who runs the food distribution. "It’s relationships, it’s loving on people, it’s hope, hope in a time of despair."Hope is just what O'Neal needed, especially after her grandson's school, and several in the area, stopped sending home-packed lunches while students were doing remote learning."That was all cut out the last of June. They didn’t give any more lunches," said O'Neal. Those programs running dry made mealtime that much tougher on O'Neal and so many others."Our school system is a completely Title 1 school system, so every child in our school system gets free lunch," said Walker.Poverty is high across most of Louisiana and in many rural communities across the country, contributing greatly to food insecurity. 2059
For the most part, we've already been sheltering in our homes as we all try to get a grip on the pandemic. And this holiday season, which started Thursday with the first day of Hanukkah, families are looking for ways to make it special.Rabbi Robert Nosanchuk says his team is helping families celebrate Hanukkah safely at home through live stream services online.“Many participants will light candles together on Zoom. So, we'll literally light up the internet,” Nosanchuk said.And while you may not be able to give gifts in person this year, you can still offer the traditional monetary Hanukkah gift virtually.But this year, Nosanchuk is asking families to focus ways to build a more peaceful and just society.“Whatever faith you may be representing, I hope you'll know that your Jewish neighbors are holding their Hanukkah menorah by the window to publicize that miracles do happen,” Nosanchuk said. “I pray strongly that we'll all be healed. We'll feel well in the new year.”This story was originally published by Taneisha Cordell at WEWS. 1051