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WASHINGTON, Dec. 21 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Wednesday approved Isentress for the treatment of HIV-1 infection for children and adolescents.The drug is part of a class of medications called HIV integrase strand transfer inhibitors that works by slowing the spread of HIV in the body. It was first approved for use in adult patients in October 2007, under FDA's accelerated approval program."Many young children and adolescents are living with HIV and this approval provides an important additional option for their treatment," said Edward Cox, director of the Office of Antimicrobial Products in the FDA's Center for Drug Evaluation and Research.Isentress is a pill that can be taken twice daily, with or without food. The pill is also available in a chewable form. As the two tablet formulations are not interchangeable, the chewable form is only approved for use in children ages 2 to 11.A single, multi-center clinical trial of 96 children and adolescents aged 2-18 years with HIV-1 infection evaluated the safety and effectiveness of Isentress. These patients previously received treatment for HIV-1 infection. After 24 weeks of treatment with Isentress, 53 percent of these patients had an undetectable amount of HIV in their blood.According to the FDA, the most commonly reported severe, treatment-related side effects in patients taking Isentress include trouble sleeping and headache. The frequency of these side effects is similar for children and adults. One pediatric patient reported severe treatment-related insomnia, while another pediatric patient experienced a drug-related skin rash.

BRUSSELS, Oct. 7 (Xinhua) --- The European Commission on Friday gave the green light to Microsoft's acquisition of voice and video communication provider Skype, thus removing the last hurdle in the process.According to a statement released by the Commission, "the deal would not significantly impede effective competition in the European Economic Area (The EU plus Iceland, Lichtenstein and Norway) or any substantial part of it."The Commission explained that it found that in the area of consumer communications, the parties' activities overlap in video communications, where Microsoft is active through its Windows Live Messenger.However, the Commission considered that there were no competition concerns in this growing market where numerous other players, including Google, were present.Skype was bought by eBay in 2005 at the price of 4.1 billion U.S. dollars, and sold out at 2.75 billion U.S. dollars in 2009. Microsoft declared to take over Skype at a cost of 8.5 billion dollars on May 10, 2011.

OTTAWA, Nov. 21 (Xinhua) -- The leader of World Health Organization (WHO) Margaret Chan said in Canada on Monday that countries must make the health of women and children their highest priority.Speaking at a luncheon in Gatineau, Quebec, Chan said that maternal and infant health is the most pressing public health issue in the world.She made the remarks just hours after WHO announced Chan was the only candidate for the position on WHO director-general when Chan's appointment expires next year.An executive board meeting in Geneva between Jan. 16 and 23 will decide whether to put the name forward to the WHO Assembly in May, which would make the final decision regarding the appointment.Chan, a former health chief in China's Hong Kong, was elected director-general of the WHO in Nov. 2006.Before her tenure with WHO, Chan was head of public health in Hong Kong, where she managed the city's response to the world's first outbreak of the deadly H5N1 bird flu virus and an outbreak of Severe Acute Respiratory Syndrome (SARS).Speaking in Gatineau, Chan, who earned her medical degree in Canada, said that she never expected to rise to such a lofty position."I just wanted to be a doctor. I just wanted to take care of women and children. When I was studying in Canada, I thought I would get married and have children. I never guessed I'd do anything like head the World Health Organization," she said.She said that she will continue to focus the WHO's attention on mothers and young children.Chan said that it's difficult to know how many mothers and young children die of preventable diseases, since more than 80 countries don't keep accurate death records, but she said that millions of children under five years of age are dying.Millions more are growing up physically and mentally stunted because of poor nutrition and medical care, she added."Without proper nutrition, the stunting we are seeing is horrific," she said. Unless babies have good food, including being breast-fed as infants, they grow up physically and mentally under-developed, Chan said."The first few years of a child's life are make or break," she said.Chan and the WHO held a meeting of the Expert Panel on Maternal and Child Health in Canada from Nov. 18 to Nov. 21. The panel was established by the United Nations Commission on Information and Accountability for Women's and Children's Health Report. At the invitation of the WHO, the Commission was co-chaired by Canada's Prime Minister Stephen Harper and the President of Tanzania, Dr. Jakaya Kikwete.Chan says she's hopeful funding from developed nations will continue to expand, despite the debt crisis facing many of them. The situation resembles the 1970s, with spikes in energy and food prices along with cuts to national budgets to restrain debt.Chan said she is relieved the International Monetary Fund will not press for public health cuts in countries that are struggling with debt.Beverley J. Oda, Minister of International Cooperation who is responsible for Canada's official aid affairs, delivered remarks at the luncheon on improving the health of children and mothers locally and globally."I am particularly proud of the strong partnership between the WHO and Canada in advancing global health, and working towards improvements that will help us achieve our shared goals," she said.Last Friday, Oda announced 25 new initiatives to further Canada 's support to 23 projects in Africa concerning Children and Youth, Food Security and Sustainable Economic Growth.Seven of these are multi-country projects supporting efforts to prevent the mother-to-child transmission of HIV/AIDS, further improving child health, or increasing the capacity of African Regional Technical Centres. The others are targeted to support work in a range of individual African countries by working with Canadian, international and African-based organizations.

WASHINGTON, Oct. 3 (Xinhua) -- Researchers at St. Michael's Hospital in Canada have discovered a new function for an enzyme that may protect against organ injury and death from anemia, according to a study appearing Monday in the U.S. journal of the Proceeding of the National Academy of Sciences.Researchers found that when people have anemia, neuronal nitric oxide synthase (nNOS) -- an enzyme in nerve cells that produces nitric oxide, an important signaling molecule in the body -- increases the body's ability to respond, adapt to low oxygen levels and makes the body more efficient in delivering oxygen to tissues. They also found that levels of nNOS in the brain increased in anemic mice, and that the mice without this enzyme die earlier, and with higher hemoglobin levels."Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study.Anemia occurs when blood has a lower than normal number of red blood cells or hemoglobin -- an iron-rich protein that carries oxygen from the lungs and heart to the rest of the body. Cells need oxygen to survive and to produce energy for all bodily functions. The condition has many different causes including infection (malaria, HIV, parasites), nutritional deficiencies (iron, folate, B12), genetic mutations, pregnancy, trauma and surgical blood loss."This research will help us identify when an anemic patient is at greatest risk for injury and death when undergoing surgery," said Hare. "Research is underway to test these findings in humans."

BEIJING, Jan. 3 (Xinhua) -- China's building materials showed different momentum of growth in November 2011, with a slowing cement output growth and a speeding plate glass, according to latest statistics from the country's top economic planner.Cement output growth in November 2011 stood at 11.2 percent year-on-year, 6.1 percentage points lower than previous year, while plate glass production expansion reached 7.1 percent year-on-year, quickening by by 0.5 percentage points from previous year.Still, China's cement output reached 1.89 trillion tonnes in the first 11 months of last year, an increase 17.2 percent year-on-year, 1.6 percentage points faster than previous year.The output of flat glass, a sector fraught with overcapacity and duplicated construction problems, rose 17 percent year-on-year to 6.82 trillion weight boxes in the January-November period of last year, according to the NDRC.Profits of China's building materials industry surged 53.1 percent year-on-year to 243.7 billion yuan (38.68 billion U.S. dollars) in the first 11 months of 2011.To curb the overcapacity and repeated construction in the flat glass sector, the NDRC said in a statement in October 2011 that it would take move nationwide to clear up projects for construction of flat glass production facilities.