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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

ISLAMABAD, Sept. 11 (Xinhua) -- Chinese ambassador to Pakistan declared on Sunday that the Chinese government will provide an emergency humanitarian aid worth 30 million RMB (4.7 million U.S. dollars) to Pakistan to help its relief efforts.In light of the immense damages caused by the floods in some parts of Pakistan, Chinese Ambassador to Pakistan Liu Jian called on Pakistani Foreign Minister Hina Rabbani Khar on Sunday to express sympathy and solidarity of the Chinese people toward Pakistani people and declared that the Chinese government will provide the emergency humanitarian aid.Diplomats and staff of the Chinese Embassy in Islamabad have recently voluntarily donated 600,000 rupee (about 6860 U.S. dollars) to the people who hit by the floods. The Chinese ambassador handed over the donation to Pakistani side on Sept. 8.On Sept. 9, Chinese Foreign Minister Yang Jiechi sent a message to his Pakistani counterpart H.E. Hina Rabbani Khar, expressing his profound condolence to the victims and sincere sympathy to the affected people of the floods.The Chinese foreign minister said that China, as Pakistan's close friend, feels as much pain as Pakistan does and is ready to provide help to the best of its ability, in line with Pakistan's needs. He is convinced that the Pakistani people will definitely prevail over the natural disaster and rebuild their homes at an early date.

WASHINGTON, Aug. 12 (Xinhua) -- NASA announced Friday the creation of a new directorate that will focus on both the International Space Station operations and human exploration beyond low earth orbit.The Human Exploration and Operations Mission Directorate combines the Space Operations and Exploration Systems mission directorates. While the transition and personnel assignments will take several weeks to finalize, the directorate already is supporting space station operations. It also will manage commercial crew and cargo developmental programs; construction of the Orion Multipurpose Crew Vehicle, a spacecraft designed to travel beyond low Earth orbit; development of a new heavy lift rocket, known as the Space Launch System; and other programs within the directorates."America is opening a bold new chapter in human space exploration," NASA Administrator Charles Bolden said in a statement. "By combining the resources of Space Operations and Exploration Systems, and creating the Human Exploration and Operations Mission Directorate, we are recommitting ourselves to American leadership in space for years to come."Associate Administrator Bill Gerstenmaier will head the new organization. He previously served as the associate administrator for Space Operations.

BEIJING, Sept. 26 (Xinhuanet) -- Weather forecasts showed that Thursday or Friday might be suitable for launching the Tiangong-1 spacecraft, experts said.The unmanned spacecraft, part of China's first spacecraft rendezvous and docking mission, was set to blast off from the Jiuquan Satellite Launch Center in Northwest China at an appropriate time between Tuesday and Friday.But the latest weather forecast showed that Tuesday and Wednesday would not be suitable for a launch, Cui Jijun, chief commander of the mission's launch site system, was quoted by China National Radio as saying on Sunday.A precondition for launching is that the average wind speed at the launch site should not be faster than 10 meters a second. The upper-level wind, at 300 meters to 25,000 meters above the Earth, should be no faster than 70 meters a second.The 8.5-ton Tiangong-1 spacecraft and the Long March II-F rocket stand at the Jiuquan Satellite Launch Center on Sept 20. The spacecraft is set to blast off at an appropriate time between Tuesday and Friday.If the wind is too strong, the rising rocket carrier could wiggle and pose a danger, experts said."Everything is ready now except for the right weather," Cui said.On Sunday afternoon, all systems of the Tiangong-1 project went through a joint maneuver, he said. Before that, the 8.5-ton spacecraft, and the Long March II-F rocket that will carry it skyward, were positioned onto the launch pad last Tuesday.Engineers carried out checkups on the conditions of the rocket and the spacecraft, among many other tests in the past few days. All preparation work is done except for fuel loading, he said.Wang Xiaoqing, a publicity official at the launch site, said that the fuel loading usually begins one day before the launch. Once the fuel is loaded into the carrier vehicle, the launch becomes "irreversible".Tiangong-1, or Heavenly Palace 1, will serve as "a target spacecraft" for three rendezvous and docking experiments.The spacecraft rendezvous and docking missions are expected to pave the way for the building of a planned space station scheduled for 2020, previous reports said.Following Tiangong-1, an unmanned Shenzhou VIII spaceship will blast off from the Jiuquan Satellite Launch Center later this year.Lu Jinrong, chief engineer of the mission's launch site system, said that it is rare that two launches of China's manned space program are scheduled in half a year."In the past, the launch site carried out one launch a year, or even one every two to three years," he said."We are already in a high-frequency launch period."

YANGON, July 10 (Xinhua) -- Myanmar is projecting to build the first-ever liver transplant hospital in line with the international standard, the local weekly Voice reported Sunday.With the technological help of the Changi General Hospital of Singapore, a 40-million-U.S dollar worth private hospital has started building since late last month.The hospital will offer services for the patients living with heart and kidney diseases and for protection from being affected Methicillin-Resistant Staphylococcus Aureus (MRSA), the report said.In Myanmar, liver transplant will cost about 20 million Kyats ( 25,000 U.S. dollars), lesser than other countries, the report added.Myanmar experts carried out successful liver-transplant operation in 2004 for the first time and in 2009 for the second time.

来源：资阳报