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BEIJING, Oct. 11 (Xinhuanet) -- An experimental drug that can remove amyloid plaques from the brains of Alzheimer's patients is being developed by Swiss Roche Holding AG in a small early-stage study, according to a report published in the Archives of Neurology on Monday.Researchers suspect the build-up of such plaques may be a cause of the memory robbing disease, although that theory has yet to be definitively proved. Gantenerumab, a biotech drug designed to bind to amyloid plaques in the brain and remove them, is being targeted at the early stages of Alzheimer's with the hope it can slow progression of the disease while patients are still able to function.The Phase I study of 16 Alzheimer's patients tested gantenerumab at two doses against a placebo over six months of treatment.The Roche drug led to a dose-dependent reduction of brain amyloid, while amyloid load increased in patients receiving a placebo, the report said.The next step will be to investigate whether removal of brain amyloid translates into clinical benefit for patients at doses of the experimental drug that are well tolerated and safe, the report said.Much larger trials and further study will be needed to fully understand how gantenerumab works and whether it can stave off Alzheimer's, said the report.Roche is approaching the disease far earlier because amyloid accumulates for 15 years before dementi.

SAN FRANCISCO, Dec. 2 (Xinhua) -- Only two weeks after its shipment, Amazon's Kindle Fire has already shown the momentum to grab the second place in global tablet computer market, research firm IHS predicted on Friday.Amazon is expected to ship 3.9 million Kindle Fire tablets during the last three months of 2011, the first quarter the product goes on sale, according to preliminary projection from IHS.The number will give Amazon a 13.8-percent share of global tablet market in the fourth quarter, surpassing the 4.8 percent held by No. 3 player Samsung, and second only to Apple's commanding 65.6 percent market share."Nearly two years after Apple Inc. rolled out the iPad, a competitor has finally developed an alternative which looks like it might have enough of Apple's secret sauce to succeed," Rhoda Alexander, senior manager of tablet and monitor research for IHS, said in a statement."Initial market response strongly suggests that Amazon, with the Kindle Fire, has found the right combination of savvy pricing, astute marketing, accessible content and an appropriate business model, positioning the Kindle Fire to appeal to a brand-new set of media tablet buyers," she added.IHS analysts noted that with a price tag of 199 U.S. dollars, the Kindle Fire has set a new bar for pricing, bringing the tablet within reach of a larger portion of the buying public.IHS expects Kindle Fire's rapid ascent to help fuel the expansion of the entire tablet market, now predicting that 64.7 million tablets will be shipped in 2011, higher than its previous forecast of 60 million issued in August.The total tablet shipment number this year will represent a 273- percent growth from 17.4 million units in 2010, said IHS, which has also increased its longer-term projection of global tablet shipment in 2015 to 287.2 million units.

BEIJING, Oct. 10 (Xinhua) -- The State Council, or China's cabinet, announced on Monday it will tax all resource products starting Nov. 1, extending the resource tax on domestic sales of crude oil and natural gas from some regions to the entire country.The list of taxable resources widened from crude oil and natural gas to coal, rare earth, salt and metal from Nov. 1, according to the country's revised resource tax regulations.The expansion of the resource tax is part of China's efforts to encourage energy conservancy and limit environmental damage.Sales of crude oil and natural gas nationwide will be taxed at a rate between five and 10 percent of their sales value, according to the revised regulations.The regulations impose a sales tax ranging from eight (1.25 U.S. dollars) to 20 yuan per metric ton on coking coal and from 0.40 to 60 yuan per metric ton on rare earth ore.Taxes on other types of coal stood unchanged at 0.30 to five yuan per metric ton.The tax rate for other non-ferrous metals is set between 0.4 to 30 yuan per metric ton. Ferrous metals will be taxed at two to 30 yuan per metric ton.Taxes on precious non-metallic ore will be between 0.5 to 20 yuan per kg or per carat, while taxes on cheap non-metallic ore are set between 0.5to 20 yuan per metric or per cubic meter.China's current resource tax is levied based on production volume instead of sales value, thus preventing the government from benefiting from energy and commodity price increases.Nonetheless, energy giants and mining companies such as PetroChina and Sinopec have enjoyed large profit margins on the sale of resources under the current tax scheme.A resource tax on oil and natural gas was introduced at a rate of five percent in northwest China's Xinjiang Uygur Autonomous Region on June 1, 2010 before being extended to 11 other provinces in December last year.

SAN FRANCISCO, Nov. 28 (Xinhua) -- Amazon.com on Monday announced that this past Black Friday was the best ever for its Kindle products with consumers buying four times as many Kindle e- readers and tablets as they did last year.According to the online retail giant, its newly launched tablet Kindle Fire was the bestselling product across all of Amazon.com on Black Friday, the day after Thanksgiving, which falls on Nov. 25 this year, when major retailers in the United States traditionally offer big discounts.Kindle Fire is Amazon's answer to Apple's popular iPad. Priced at 199 U.S. dollars, the Amazon product is much cheaper than iPad which starts from 499 dollars.Survey results by research firm ChangeWave Research released days before Black Friday indicated that Amazon is poised to become the No. 2 player in the tablet computer market behind Apple, due to strong demand for Kindle Fire.Amazon said Black Friday sales also showed that a lot of customers were buying multiple Kindles, one for themselves and others as gifts.The trend is expected to continue through this holiday shopping season, Amazon's vice president of Kindle products Dave Limp said in a statement.

BEIJING, Oct. 11 (Xinhuanet) -- An experimental drug that can remove amyloid plaques from the brains of Alzheimer's patients is being developed by Swiss Roche Holding AG in a small early-stage study, according to a report published in the Archives of Neurology on Monday.Researchers suspect the build-up of such plaques may be a cause of the memory robbing disease, although that theory has yet to be definitively proved. Gantenerumab, a biotech drug designed to bind to amyloid plaques in the brain and remove them, is being targeted at the early stages of Alzheimer's with the hope it can slow progression of the disease while patients are still able to function.The Phase I study of 16 Alzheimer's patients tested gantenerumab at two doses against a placebo over six months of treatment.The Roche drug led to a dose-dependent reduction of brain amyloid, while amyloid load increased in patients receiving a placebo, the report said.The next step will be to investigate whether removal of brain amyloid translates into clinical benefit for patients at doses of the experimental drug that are well tolerated and safe, the report said.Much larger trials and further study will be needed to fully understand how gantenerumab works and whether it can stave off Alzheimer's, said the report.Roche is approaching the disease far earlier because amyloid accumulates for 15 years before dementi.

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