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Scientists are working to eliminate a type of heart disease in dogs using gene therapy. They're zoning in on a heart condition called mitral valve disease that’s common in 6% of dogs. Scientists are using Cavalier King Charles spaniels for the research. They tend to develop it at a younger age. Scientists at Tufts University have already tested gene therapy in mice. A virus is injected into them to deliver DNA to cells which causes them to create a protein. What it essentially does is stops the heart valve from getting thicker, stopping the valve from leaking. Researchers are now moving on to testing this in dogs. But they think the treatment could go beyond just canines. “Many of the dog diseases are naturally occurring and really great models for human disease,” says Dr. Vicky Yang, a veterinary cardiologist and research assistant professor at Cummings School of Veterinary Medicine at Tufts University. “And I can see this, if it becomes successful in dogs, potentially going into thinking about treatment for humans for mitral valve disease.”The biotech company behind the treatment agrees. It says it could also expand beyond heart problems. “I think a larger question, though, is if we are able to prove this thesis of treating aging, making the animal generally healthier, could also treat heart failure, what other diseases could we treat in dogs?” says Daniel Oliver, the CEO of Rejuvenate Bio. “And could we progress this treatment onto past dogs and other animals and possibly humans?” The gene therapy would only be used for dogs just starting to experience heart problems.Researchers still need to make sure the gene therapy is safe for all breeds before they make it available to the public. 1730

The challenge #TrashTag is a viral trend taking over social media. People all over are cleaning up the environment and sharing it online. Although a new trend online, it’s something nature lover Caitlin Deporter has already been doing for nearly a decade. The beauty of the outdoors is something Deporter has always cherished. "It's just grown from a young age, an appreciation for everything natural," Deporter says. She spends a lot of her time hiking near the Potomac River in Maryland. "My dad and I usually do our big hiking trips together," she says. Along those hikes, Deporter says she sees a lot of garbage. "There are a lot of beer cans and bottles, I will tell you that," she says. Americans produce more than 250 million tons of waste annually, according to the EPA. Keep America Beautiful reports .5 billion is spent yearly cleaning it all up. However, Deporter is doing one simple thing to curb those statistics. “I'll bring a normal size trash bag and a backpack and get prepared for a day of work,” she says. For the last eight years, on her bi-weekly hikes, she brings a trash bag with her every time, picking up all the litter she sees along the way. "I'm concentrating on getting trash where it's supposed to be," she says. She does something small to help combat a big problem. "I'm just one person; I can only do so much," she says. She’s hoping the #TrashTag movement keeps up, for the sake of the environment."I hope this whole trend really sticks, and it's not just you know people do it for a week to get all their photos in and look all cool, you know,” Deporter says. “I really hope people continue to do it." 1658

A 14-year-old girl was arrested and charged with murder after police say she tied down and killed a 59-year-old Philadelphia man known for his animal rescue efforts.Philadelphia police said they responded early November 5 to a report of a man in distress. Police entered the home and found a man, later identified as Albert Chernoff, partially tied to the bed with a massive head wound and several slashes to his chest. He was pronounced dead at the scene.A female was seen leaving the property before police arrived, and police released surveillance video from inside the home in an attempt to identify her. The girl, who is 14, arrived with her mother and two defense attorneys to turn herself in, police said.She was arrested November 8 and a preliminary hearing is scheduled for November 27, court documents show. Given her arrest, the surveillance video has since been removed, police said.Police have not named the girl.Jane Roh, a spokeswoman for the Philadelphia district attorney, said officials have not decided whether to proceed in juvenile or adult court.One of the teenager's attorneys, Howard Taylor, told CNN the girl is currently in juvenile detention."It's a very sad situation. Troubled girl. There's a reason police aren't saying much," Taylor said. "There's a lot more to it."When asked whether she was a victim, he said he "wouldn't put it to that extent," but added that "he wasn't totally innocent, either."Chernoff was a well-known animal rescue advocate in Philadelphia. In the wake of his death, the makers of the documentary film " 1571

A lawsuit has been filed against the food delivery driver accused of stabbing a local restaurant owner.On Oct. 27, 2018, Mackie Allen was waiting in the parking lot for his DoorDash delivery run to be ready. Roma Deli & Restaurant owner Fabio Coppola came out and knocked on his window to let Allen known the food was ready — that’s when he says Allen became hostile. Once inside, Coppola says the DoorDash driver started screaming obscenities at him. Despite his efforts to calm him down, Copolla said he would file a complaint against DoorDash because of Allen’s behavior. That’s when Allen allegedly lost it, pulled out a pocket knife and slashing Coppola’s left hand. The owner says he ran for his life, and that Allen then stabbed him in the ribs below the heart and in the back multiple times outside. It’s believed Allen then delivered the food from Roma Deli to the DoorDash customer. “This is a life or death situation,” says Donavin Britt, self-defense expert. Britt has been teaching folks how to protect themselves at Las Vegas Krav Maga for years and knows all too well the dangers the food service industry faces now more than ever.“You have to devise a plan, all business owners out there are known to carry cash, you’re moving back and forth, you’re dealing with unruly customers,” says Britt.“You got to be ready to take them down or run as fast as you can.” With food delivery services on the rise like DoorDash and Uber Eats, Britt believes the threat is amplified. The attorney representing Copolla and his wife are holding DoorDash accountable, and claims Allen had prior felony convictions. Attorney Richard Schofeld says “DoorDash's flawed background check policy almost cost Mr. Coppola his life. This case raises important questions in terms of the minimum standards that should be required to protect both consumers and restaurant workers.”DoorDash sent the following statement: 1921

A court in Saudi Arabia on Monday sentenced five people to death for the killing of Washington Post columnist Jamal Khashoggi, who was murdered in the Saudi Consulate in Istanbul last year by a team of Saudi agents.The verdicts were read by Shaalan al-Shaalan, a spokesperson from the attorney general's office, and broadcast on Saudi Arabia's state-run Al-Ekhbariya TV.No names were given for those found guilty. Al-Ekhbariya reported that three others were sentenced to prison.All can appeal the verdicts.The Saudi crown prince, Mohammed bin Salman, had drawn international condemnation for the killing because several Saudi agents involved worked directly for him.The kingdom denies that Prince Mohammed had any involvement or knowledge of the operation.The killing had shocked the world and drawn condemnation from the international community, including the United Nations.Khashoggi had walked into his country's consulate in Istanbul on that morning in October 2018 to collect documents that would allow him to wed his Turkish fiancée, Hatice Cengiz, who waited for him outside.He never walked out.Khashoggi's body was never found. 1148