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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.
SYDNEY, Nov. 10 (Xinhua) -- Children with fat fathers are more likely to be obese by age of eight or nine than those with healthy weight fathers, a new study by researchers at Australia's University of Newcastle found on Thursday.Researchers at the University of Newcastle found that children who had an overweight or obese dad were four times more likely to follow in their father's footsteps than those with a dad in the healthy weight range.They also found in the study that only having an obese or overweight mum in the family did not have the same effect.Lead researcher Emily Freeman said it was still unknown why overweight dads had such a significant effect on their children's weights.The researchers conducted their study using data collected from 3000 Australian families between 2004 and 2008 for a longitudinal study.They looked at the weights of children when they were aged four to five and then again when they turned eight and nine years old.According to Freeman, around 25 percent of Australian children are overweight or obese.She said helping fat dads lose weight could make a difference to the youngsters.
BEIJING, Dec. 31 (Xinhua) -- In a New Year's address broadcast on Saturday, Chinese President Hu Jintao vowed that China will continue to develop friendly exchanges with other countries and positively participate in international cooperation on global issues.While addressing domestic and overseas audiences via state TV and radio broadcasters, Hu urged the acceleration of the transformation of the country's economic development pattern and structural adjustments while making more efforts in ensuring people's livelihood.The country will continue to balance maintaining steady and relatively fast economic growth with adjusting its economic structures and managing inflation expectations, he said in the speech titled "Jointly Improve World Peace and Development," which was broadcast by China Radio International, China National Radio and China Central Television.A photo released on Dec. 31, 2011 shows Chinese President Hu Jintao delivering a New Year address, titled "Jointly Improve World Peace and Development", to domestic and overseas audiences via state TV and radio broadcasters.China will stick to the guidelines of "one country, two systems," "Hong Kong people governing Hong Kong," "Macao people governing Macao," and a high degree of autonomy in maintaining the long-term prosperity and stability of Hong Kong and Macao, Hu said."We will adhere to the principles of 'peaceful reunification' and 'one country, two systems,' continue to push forward the peaceful development of cross-Strait relations, ensure the basic benefits for those of the Chinese nationality, and endlessly work for the common benefit of the compatriots on both sides of the Taiwan Strait," he said.2011 was the first year of the country's 12th Five-Year Plan period (2011-2015). In the face of complicated international situations and arduous tasks in maintaining domestic reform, development and stability, Chinese people united and continued to push forward the opening up and reform drive and the socialist modernization construction, while maintaining steady and relatively fast economic growth and making progress in building a well-off society in an all-around way, he said.China was also actively engaged in international cooperation to boost the growth of the global economy and financial stability, and it was involved in resolving international and regional issues, he said.The world is currently witnessing multipolarization and globalization, and various countries are increasingly interdependent, Hu said."However, the instability and uncertainty of the world economic recovery is on the rise, international and regional hot-topic issues have cropped up one after another, and the peace and development of the world faces unprecedented opportunities and challenges," Hu said.China will stick to peace, development and cooperation, adhere to independent foreign policy, maintain world peace and promote common development, Hu said.The country will stick to the principle of mutual benefit when opening itself up, he said."We will develop friendly cooperations with all countries on the basis of the five principles of peaceful co-existence, and we will continue to actively participate in international cooperation on global issues," Hu said."I believe that as long as people from all countries make efforts hand-in-hand, the world will have a better future and the welfare of the people of all countries will improve," Hu said.An article by Hu on boosting the country's cultural development will be published in Qiu Shi (Seeking Truth), an official magazine of the Communist Party of China Central Committee, on Jan. 1.
BEIJING, Jan. 1 (Xinhua) -- The public on Sunday strongly echoed Chinese President Hu Jintao's New Year address broadcast on Saturday, vowing to make great efforts for rejuvenation of the nation, a better future.In his speech titled "Jointly Improve World Peace and Development," Hu said that China will continue to develop friendly exchanges with other countries and positively participate in international cooperation on global issues.The country will continue to balance maintaining steady and relatively fast economic growth with adjusting its economic structures and managing inflation expectations, Hu said in the speech.PROUD Of COUNTRY'S ACHIEVEMENTS"We have been encouraged by President Hu's address, said Wang Laihua, head of the public opinions research institute of Tianjin Social Sciences Academy."His address summarized the achievements that we have made in the first year of the 12th Five-Year Plan, which raised people's expectation for prosperity, happiness," said Wang.Hu said in the address that in the face of complicated international situations and arduous tasks in maintaining domestic reform, development and stability in 2011, Chinese people united and continued to push forward the opening up and reform drive and the socialist modernization construction, while maintaining steady and relatively fast economic growth and making progress in building a well-off society in an all-around way.Zhu Jianfang, chief economist of CITIC Securities, said that the country's macroeconomic control has made positive achievements in the last year, as the prices of properties and commodity have been effectively controlled."We feel reassured after hearing Hu's speech," said Wen Jun, who has come to south China's Guangzhou for business from Hong Kong for 16 years, referring to Hu's speech saying that China will stick to the guidelines of "one country, two systems," "Hong Kong people governing Hong Kong," "Macao people governing Macao," and a high degree of autonomy in maintaining the long-term prosperity and stability of Hong Kong and Macao.