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SAN DIEGO (KGTV) — Local leaders say it's going to cost millions of dollars to prevent toxic waste from flowing into the Tijuana River Valley, but it's a bill they are willing to pay. Dozens of local leaders and federal agencies came together this morning with a common goal, to prevent the massive amounts of sewage from flowing into our San Diego County beaches. "427 million gallons of sewage has hit our water and our beaches just this year alone," says Port of San Diego Commissioner, Dan Malcolm. During today's meeting, leaders were given possible solutions on how to tackle the problem. "To divert sewage and wastewater flow away from the Tijuana River Valleys, so that it can either be treated or diverted to outflow pumps, that would pump the water far out in the Pacific Ocean," says Mayor of Coronado Richard Bailey.The costs are estimated up to 0 million. Local leaders say sewage isn't the only contaminate in the water. A chemical test was done that showed things like herbicides, arsenic, and lead are also flowing into the sea. "The time of talk is over," says Serge Dedina, Mayor of Imperial Beach. "The time of actually doing things and preventing sewage and toxic waste from reaching our beach is now."Local leaders say the next plan of action is to ask Congress for help with funding. Mayor Kevin Faulconer and Mayor Serge Dedina will be visiting Mexico over the next few days to talk about solutions to the waste in the Tijuana River Valley. 1475

SAN DIEGO (KGTV) — It’s one of the few drugs shown to help fight the novel coronavirus, and a large federal study on remdesivir just entered a new phase.Previous research sponsored by the National Institute for Allergy and Infectious Disease showed remdesivir shortened recovery time in hospitalized COVID-19 patients on average from 15 days to 11 days.Now scientists and doctors are racing to find the perfect cocktail against COVD-19 by blending remdesivir with other drugs.California-based Gilead Sciences originally developed the drug to fight Ebola, but remdesivir was never approved. Gilead Sciences has offices in Oceanside.The drug works by interrupting the virus’ ability to replicate.“Remdesivir acts by shutting down virus production,” said Dr. Peter Chin-Hong, an infectious disease expert at University of California San Francisco. “It just forces the virus to stop making virus children.”Dr. Chin-Hong is studying remdesivir as part of the NIAID research.The problem is that stopping the virus from replicating isn’t enough for some severely ill patients. They suffer from a second problem: massive inflammation from the immune system’s war with the virus.That’s why scientists are trying a cocktail approach.“You have the virus to take care of, but you also have the body's response to the virus, which is inflammation, that you also have to take care of,” said Dr. Chin-Hong.Researchers started testing the first drug cocktail in May, using an arthritis drug called baricitinib that tames inflammation.But as the data on that part of the study gets crunched, researchers began testing the second cocktail this month, a combination of remdesivir and interferon beta.“Interferon beta is something we produce naturally to fight viruses,” said Dr. Chin-Hong. He said studies have shown people who don’t produce enough interferon beta struggle to fight off the virus.Researchers selected interferon beta after two small studies showed promising results against the coronavirus.Interferon beta can both reduce inflammation and kill viruses, so doctors are hoping it will be a potent one-two punch with remdesivir.Dr. Chin-Hong said he and other researchers started administering the new cocktail this month.Some patients will receive the cocktail, some will receive a placebo, and some will get remdesivir only. This kind of clinical trial is called an adaptive trial, which the FDA started encouraging in 2004. After each phase, the winning drug or cocktail will be tested against a new challenger.Dr. Chin-Hong said the eventual cocktail may include three or more drugs, similar to HIV medication. 2617

SAN DIEGO (KGTV) — If Pfizer's coronavirus vaccine is approved this week, UC San Diego Health anticipates receiving its first allocation of the vaccine next week.The vaccine will be considered on Thursday by the Food and Drug Administration. Once it receives the vaccine, UC San Diego Health says its first vaccinations could occur shortly after."Assuming the U.S. Food and Drug Administration issues an Emergency Use Authorization tomorrow or Friday, we would anticipate arrival of the first allocation of the Pfizer vaccine to UC San Diego Health next week, with the first vaccinations occurring shortly thereafter," a statement from the hospital system said. RELATED: What phased vaccine distribution will look like in San Diego CountyThe hospital system says the process of receiving and distributing the vaccine remains fluid and details still need to be finalized.Who will receive the vaccine first will be based on the CDC's Advisory Committee on Immunization Practices, which recommends health care workers receive the vaccination first, along with residents and workers of nursing homes and long-term care facilities.RELATED: What the FDA's review reveals about Pfizer's COVID-19 vaccinePrioritization of who in those first groups receives a vaccination first will also depend on doses available. But those health care workers who face the greatest exposure to COVID-19 patients will be prioritized.This week, an outside group of vaccine experts will advise the FDA and vote on whether to recommend an emergency use authorization for the drug.FDA scientists independently confirmed Pfizer’s claim that its vaccine is 95% effective after two doses and said they found no serious safety concerns, according to documents released Tuesday.Upon approval, California is set to receive 327,000 doses of the vaccine in the first round of allocation. Of those San Diego County is scheduled to receive 28,275 doses. The second round of vaccine allocation is expected within 3-4 weeks. 1991

SAN DIEGO (KGTV) - If you're looking to strike gold with some St. Patrick's Day fun this weekend, you're in luck!This weekend, some of San Diego's favorite St. Patrick's Day events are returning. San Diego ShamROCK, arguably the biggest event in town, will take over the Gaslamp District with multiple stages of entertainment and fun.The "Irish 4 a Day" party hop will also keep the partying running through the night into Saturday, offering music and drink specials at participating nightclubs.RELATED: More San Diego family funSpeaking of running, get in some activity before going out at the St. Patrick's Day 10K in Mission Bay or St. Patrick's Day 5K and 15K in Temecula.And, of course, don't miss San Diego's annual St. Patrick's Day parade and festival in Balboa Park, where thousands are expected to take in the sights, sounds, and smells of the holiday.Here's more on this weekend's fun:FRIDAY"Irish 4 a Day" Party HopWhere: Gaslamp District; Cost: - 0(Runs Friday through Saturday) San Diego's "longest-running" St. Patrick's Day party. Two days of DJs, live music, green beer, and more will take place across participating Gaslamp District nightclubs. 1202

SAN DIEGO (KGTV) — In lieu of traditional Dia de los Muertos events that invite San Diegans to honor their loved ones in-person, the county is hosting a virtual festival this year.San Diego County's Parks and Recreation Department will hold a virtual celebration from 1 p.m. to 3 p.m. on Sunday, Nov. 1. The online festival will feature dance performances, a cultural storytime, and an arts and crafts workshop:The festival will also include a tour of the Rancho Guajome Adobe, an authentic 1850s adobe hacienda located in Vista that is listed on the National Register of Historic Places.The holiday originated thousands of years ago in Mesoamerica (Mexico and northern Central America). Dia de los Muertos is not a somber holiday. Rather than mourning, ancient Aztecs, Mayans, and Toltec celebrated and honored the dead by providing food, water, and tools to aid their journey into the afterlife. These are the days their souls were believed to return to earth, and altars were used to help them find their way home.Today, the ritual has grown beyond Mexico but continues as a show of appreciation for the joy our loved ones brought to our lives.During Dia de los Muertos, we honor those that passed away with colorful arts and crafts, foods, costumes, and parades. Offerings are often set around a brightly decorated altar, known as “offrendas,” which includes radiant marigold flowers, decorated “calaveras” (skulls), photos, desserts, and candles.Participants of today's festivities can pick up craft kits free of charge, though a donation is appreciated, from five county parks and community centers this weekend, including:Heritage County Park: 2454 Heritage Park Row, San Diego; Hours: 9 a.m. – 5 p.m. daily; Phone: 877-565-3600Rancho Guajome Adobe: 2210 N. Santa Fe Ave., Vista; Hours: (Visitor Center and Adobe): 9:30 a.m. – 4 p.m. Wednesdays through Sundays; Phone: 760-724-4082San Elijo Lagoon Ecological Reserve and Nature Center: 2710 Manchester Avenue, Cardiff-by-the-Sea; Hours: 9 a.m. – 5 p.m., daily; Phone: 760-634-3026Sweetwater Summit Regional Park: 3218 Summit Meadow Road, Bonita; Hours: 9:30 a.m. – sunset, daily; Phone: 619-472-7572Waterfront Park: 1600 Pacific Highway, San Diego; Hours: 8 a.m. – 6 p.m. daily; Phone: 619-232-7275Participants are encouraged to call ahead of time to make sure supplies are still available.Old Town San Diego is not holding its annual Dia de los Muertos events, but businesses in the area will display altars, art, and decorations to mark the day from Oct. 15 - Nov. 17.MORE VIRTUAL EVENTSCOVID-19 Altar de Muertos: In honor of Dia de Muertos and the nearly 900 San Diegans who have died due to COVID-19, San Diego County Supervisor Nathan Fletcher and Assemblywoman Lorena Gonzalez, D-San Diego, will hold a Day of the Dead ceremony Sunday at the County Administration Center."The COVID-19 Altar de Muertos is our way of remembering those we have lost to this horrible virus," said Fletcher, co-chair of the county's COVID-19 Subcommittee."It provides an opportunity to reflect on the effect COVID-19 has had on all communities, but we should be paying special attention to the disproportionate impact it has made on Black, Brown and other communities of color. Every death because of COVID counts. Every life lost to COVID matters. It is now time to rededicate ourselves to protecting one another by taking the actions needed to slow the spread," he said.The ceremony at 5:30 p.m. to dedicate the COVID-19 Altar de Muertos will be live streamed. Viewing locations will be on Fletcher's Facebook and Twitter, https://www.facebook.com/SupervisorFletcherSD/ and https://twitter.com/SupFletcher. 3661

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