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Excessively high or low body mass index measurements have been linked to an increased risk of dying from nearly every major cause except transport accidents, new research says.The?study, published Wednesday in The Lancet Diabetes and Endocrinology and conducted by scientists at London School of Hygiene and Tropical Medicine, revealed that BMI that's either too high or too low is tied to increased morbidity from a range of major diseases.Krishnan Bhaskaran, lead author of the study and associate professor of statistical epidemiology, noted that his team found "important associations" between BMI and most causes of death."BMI is a key indicator of health. We know that BMI is linked to the risk of dying overall, but surprisingly little research has been conducted on the links to deaths from specific causes," he said."We have filled this knowledge gap to help researchers, patients and doctors better understand how underweight and excess weight might be associated with diseases such as cancer, respiratory disease and liver disease."BMI is determined by dividing a person's weight in kilograms by the square of their height in meters.The study authors say they discovered that maintaining a BMI in the range of 21 to 25 kg/m2 is linked to the lowest level of morbidity.BMI outside this range was shown to have a "J-shaped association" with nearly all causes of death, not solely the most prevalent diseases. This means BMIs both lower and higher than the optimal range lead to increased risk of morbidity.The study, which analyzed data from 3.6 million people and 367,512 deaths, showed that obesity, or BMI of 30 or more, was linked to an increased prevalence of two major causes of death: heart disease and cancer."BMI higher than 25, the upper end of healthy, is linked to most cancers, most cardiovascular diseases, respiratory disease, and liver and kidney conditions," Bhaskaran said.Obesity was shown to reduce life expectancy by 4.2 years in men and 3.5 years in women, and it can contribute to other chronic conditions including respiratory disease, liver disease and diabetes.The British Journal of Cancer reported in April that obesity is linked to 7.5% of cancers in UK women.The charity Cancer Research UK estimated that 23,000 women will deal with obesity-related cancers by 2035. Obesity will also become the most common cause of cancer in women by 2043 if trends continue.The study also revealed that being underweight is linked to a "surprising wide range of deaths," including dementia, Alzheimer's, cardiovascular disease and suicide.However, Bhaskaran noted that links between low BMI and causes of death were more "observative," as it was less clear whether low weight was the direct cause of illness or rather a marker of poor health more generally.He also acknowledged the limitations of the study, which included a lack of information on the diet or level of physical activity of the individuals involved and the impact these factors may have had on morbidity.He nevertheless noted that the findings reiterated the importance of maintaining a BMI within the 21 to 25 range. 3130

Every day, 20 veterans reportedly take their lives due to post-traumatic stress disorder (PTSD). Now, a party drug is proving to be a promising, yet controversial, alternative therapy to treat PTSD and depression.For 11 years, Patrick, a former airman, suffered from PTSD. He said he got to a point where he felt he tried everything.   "I stayed home all the time,” he says. “I didn't get out the depression, the anxiety and the thoughts of suicide, every day."   Patrick says he found a glimmer of hope three months ago, when Veterans Affair signed off on an alternative treatment called ketamine therapy. Doctors administer a very low dose of ketamine, popularly known as “Special K.”    "Basically, it's an infusion through an IV," Patrick explains.   Some users say it feels like you're experiencing an alternative reality, but it's the immediate results after treatment that has patients seeing life through a different lens.    "I feel like someone turned on the light in the dark room,” Patrick says. “That now, I can see. Now, I can really proceed with my day."  The opioid crisis has created a cause for concern for abuse of ketamine. However, Dr. Steven Levine, the CEO of Actify Neurotherapies where Patrick goes, says this treatment is different than prescription medication.    "Most importantly, if the medicine is restricted to a controlled medical setting and people don't have it at home just to take it whenever, they feel like it that makes all the difference," Dr. Levine says.  Ketamine therapy might not be for every veteran living with PTSD, but for Patrick, it gave him his life back."I’m just thankful this program is out there and that it works for me," he says.   1778

ESCONDIDO, Calif. (KGTV) -- The man accused of hitting and killing an Escondido bicyclist appeared in court Wednesday on unrelated charges. Jamison Connor, 41, pleaded not guilty at his arraignment. The charges were unrelated to the deadly hit-and-run and were instead a result of parole violations in which Connor was found with a bag of methamphetamine and a loaded gun during a traffic stop. Also in the truck at the time of the stop was Connor's young son, prosecutors say. The District Attorney's office went into detail outside the courtroom about the arrest. "During their investigation, police noted several signs and symptoms the defendant was under the effect of controlled substances and alcohol," said Assistant DA Chris Campbell. RELATED: Grieving family learns of hit-and-run arrest on Thanksgiving holidayEscondido Police pulled Connor over Thanksgiving morning, driving with his four-year-old son. "When they took the defendant out, law enforcement searched the truck. They found a bag of meth in passenger side door and loaded 25 caliber firearm in glove compartment."After his arrest, police announced Connor as the suspect in a hit-and-run crash that killed 36-year-old Kevin Lentz. Lentz was cycling with a group along La Honda Road north of El Norte Parkway when he was hit head-on November 23. “The driver of the car was on the wrong side of the road, traveling at high speed on a blind curve when he hit Kevin head-on, killing him instantly,” wrote Devin Rickey on a GoFundMe page set up for Lentz’ family.RELATED: Friends mourn bicyclist killed in hit-and-run crashOfficers later found a dark Toyota sedan abandoned about a half-mile away from the crash on the 600 block of Aster Street. Police say the vehicle had significant damage to the windshield and roof. Lentz raced competitively for the TASCO MTB mountain bike team before scaling back his riding to spend more time with family and friends. He married his wife Lauren in 2016. 1968

Every year, millions of kids across the country look forward to dressing up, knocking on doors and celebrating Halloween with lots of candy. But this year, the pandemic is likely changing some of those celebrations.So, is it still possible to celebrate Halloween this year?"That's a great question. I'm not just a doctor, but I'm also a parent to three young boys who are of trick-or-treating age. So, it's certainly a question that gets asked a lot in my wife's pediatric practice, as well,” said Dr. Kenny Banh, an emergency room physician and assistant dean of undergraduate medical education at UCSF-Fresno. “I have to say, I don't want to give a blanket answer, because it really depends on where you are and what the numbers are."Dr. Banh says there are ways to trick-or-treat this Halloween, but you first have to look at your local city and county ordinances."There’s simple things of just maintaining the guidelines. How do you do a mask? There are ways to incorporate masks in a costume and make sure we make or get costumes with masks integrated into them and trying to maintain social distancing,” suggested Dr. Banh. “The good thing about candy is years ago we moved away from homemade candies. Almost all candy is packaged already, so that’s helpful.”Still, limiting the number of people who touch the candy is a good idea along with wiping down the packaging.If you're wanting to pass out candy this Halloween, it's best to do it with a mask on and try to limit the number of trick or treaters handling the candy."Some recommendations are prepackaged candy, give little candy gift bags people can grab as they get by, instead of having kids reach in with their hands and grabbing a bunch of stuff, or you passing out with gloves or getting tongs and just dropping them into or getting a scooper letting kids drop it in," said Dr. Banh.Dr. Banh's biggest concern is with Halloween parties."Having Halloween parties and getting kids from the neighbors or friends all together, that’s really different than you as a nuclear group going as a family going out trick-or-treating and doing it safely,” said Dr. Banh. “Trying to understand that we’re finally making some ground in many states and we can easily go backwards. Labor Day, Halloween all these things sort of letting our guard down on those aspects.”Doctors say it's important to stay vigilant when it comes to protecting yourself from coronavirus so that the only frightening things we're encountering this Halloween are scary costumes and decorations. 2530

Ellen DeGeneres is considering ending her run on daytime talk.DeGeneres told the New York Times in a new interview that she's mulling what to do once her contract comes to an end in 2020.DeGeneres renewed her deal in 2016 but had been "close to declining" the offer that would have kept her in front of daytime audiences through Season 17, according to the Times.The comedian and host reportedly is torn between advice given to her from two significant people in her life: her brother and her wife, actress Portia de Rossi."She (de Rossi) gets mad when my brother tells me I can't stop," DeGeneres told the Times.De Rossi, meanwhile, told the Times that she believes her wife has "other things she could tackle.""The Ellen DeGeneres Show" has won 57 Daytime Emmys since its debut in 2003. 806