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A large fire broke out early Friday at a refinery in Philadelphia, the city fire department told CNN.The fire started at Philadelphia Energy Solutions between 3 and 4 a.m., according to CNN affiliates.Residents reported several explosions that were felt in South Jersey and Delaware County, Pennsylvania, according to CNN affiliate 344

Scientists are working to eliminate a type of heart disease in dogs using gene therapy. They're zoning in on a heart condition called mitral valve disease that’s common in 6% of dogs. Scientists are using Cavalier King Charles spaniels for the research. They tend to develop it at a younger age. Scientists at Tufts University have already tested gene therapy in mice. A virus is injected into them to deliver DNA to cells which causes them to create a protein. What it essentially does is stops the heart valve from getting thicker, stopping the valve from leaking. Researchers are now moving on to testing this in dogs. But they think the treatment could go beyond just canines. “Many of the dog diseases are naturally occurring and really great models for human disease,” says Dr. Vicky Yang, a veterinary cardiologist and research assistant professor at Cummings School of Veterinary Medicine at Tufts University. “And I can see this, if it becomes successful in dogs, potentially going into thinking about treatment for humans for mitral valve disease.”The biotech company behind the treatment agrees. It says it could also expand beyond heart problems. “I think a larger question, though, is if we are able to prove this thesis of treating aging, making the animal generally healthier, could also treat heart failure, what other diseases could we treat in dogs?” says Daniel Oliver, the CEO of Rejuvenate Bio. “And could we progress this treatment onto past dogs and other animals and possibly humans?” The gene therapy would only be used for dogs just starting to experience heart problems.Researchers still need to make sure the gene therapy is safe for all breeds before they make it available to the public. 1730

A 62-year-old former Marine reclaimed a world record he originally set in 2011 by holding an abdominal plank for an astonishing eight hours earlier this month, the 176

A doggy play date in a North Carolina pond turned tragic after three pups died from toxic algae. Now, their owners say they hope their loss will educate fellow dog lovers about the dangerous blooms.Melissa Martin and Denise Mintz took their beloved dogs Abby, Izzy and Harpo to a pond in Wilmington on Thursday night to cool off. But within 15 minutes of leaving the pond, Abby, a West Highland white terrier, began to have a seizure.Martin rushed her to a veterinary hospital, with Izzy and Harpo right behind her. Upon their arrival, Izzy, also a Westie, started seizing, and both terriers rapidly declined. Then Harpo, her 6-year-old "doodle" mix therapy dog, began to seize and show signs of liver failure.By midnight Friday, all three dogs had died, she said.The culprit, Martin's veterinarian said, was poisoning from blue-green algae present in the pond where they played."What started out as a fun night for them has ended in the biggest loss of our lives," Martin wrote in a 996

A high school student who was born in the United States and is a US citizen was released from ICE custody on Tuesday after spending three weeks behind bars, his lawyer told CNN.Word spread of the teen's detention after the Dallas Morning News first reported it Monday, and immigrant rights advocates pointed to the case as a sign that US immigration authorities are going too far as they crack down on illegal immigration.US Customs and Border Protection and Immigration and Customs Enforcement haven't responded to CNN's requests for comment on the case.Claudia Galan, an attorney representing 18-year-old Francisco Galicia's family, says they still have questions about why immigration authorities held a US citizen in custody for three weeks, but they're relieved he's been released.He was on his way to a college scouting event on June 27 when 860