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By 1969, Bloomingdale's exclusively sold Lauren's men line, the first time the Manhattan department store had given a designer his own in-store shop. In 1971, Lauren introduced the Polo player emblem with a line of tailored shirts for women and opened the first freestanding store for an American designer in Beverly Hills, California.

But the senator will have work to do to build a national profile. She barely registers in early opinion polls of potential Democratic candidates.

By Sunday afternoon, the Sina Weibo hashtag of the incident had received more than 510 million views on the platform. The apology was also one of the most searched topics of the day on Chinese search engine Baidu, with more than 6.3 million searches.

But the White House announced on Sept 2 that the US will refuse to join in, or cooperate with, COVAX. "The United States will continue to engage our international partners to ensure we defeat this virus, but we will not be constrained by multilateral organizations influenced by the corrupt World Health Organization and China," said White House spokesman Judd Deere.

By 2019, the European Union had been China's top trade partner for 16 consecutive years, with a total trade volume exceeding 0 billion for the first time last year, he said.