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After a transcontinental flight on the “Panda Express,” a furry American darling arrived early Thursday in his new Chinese home.The Washington-born giant panda Bei Bei was a beloved figure at the National Zoo, where he spent the first four years of his life. By agreement with the Chinese government, the zoo had to return Bei Bei to China this year.He is now settling into the Ya’an Bifengxia Base of the Giant Panda Conservation and Research Center in southwest Sichuan province. Bei Bei will be quarantined for one month while he adjusts to the time difference, learns to eat local foods and picks up Sichuanese dialect, state broadcaster CCTV reported.Bei Bei was conceived through artificial insemination and born to the National Zoo’s Mei Xiang and Tian Tian in 2015. His name, which means “treasure” in Chinese, was jointly selected by then-first lady Michelle Obama and Chinese President Xi Jinping’s wife, Peng Liyuan. Bei Bei quickly became a favorite on the zoo’s Panda Cam, and fans bid a bittersweet farewell to the cub online with the hashtag #byebyebeibei.With his handler, a veterinarian and 23 kilograms (66 pounds) of bamboo in tow, Bei Bei flew on a private jet provided by the shipping company FedEx and with a panda painted on its fuselage.The giant panda offers a bright spot during a dark period in U.S.-China relations, as the two countries have been embroiled in a long trade dispute.Once Bei Bei reaches sexual maturity at age 6, he will enter China’s captive breeding program, which is credited with bringing giant pandas back from the brink of extinction. They live mainly in Sichuan’s bamboo-covered mountains and are threatened by habitat loss.Bei Bei appeared to be adapting well to his new environment Thursday. He ate 6 kilograms (13 pounds) of bamboo for breakfast, CCTV said. 1822

A pinch in the leg, a squeal and a trickle of tears. One baby after another in Malawi is getting the first and only vaccine against malaria, one of history’s deadliest and most stubborn of diseases.The southern African nation is rolling out the shots in an unusual pilot program along with Kenya and Ghana. Unlike established vaccines that offer near-complete protection, this new one is only about 40% effective. But experts say it’s worth a try as progress against malaria stalls: Resistance to treatment is growing and the global drop in cases has leveled off. With the vaccine, the hope is to help small children through the most dangerous period of their lives. Spread by mosquito bites, malaria kills more than 400,000 people every year, two-thirds of them under 5 and most in Africa.Seven-month-old Charity Nangware received a shot on a rainy December day at a health clinic in the town of Migowi. She watched curiously as the needle slid into her thigh, then twisted up her face with a howl.“I’m very excited about this,” said her mother, Esther Gonjani, who herself gets malaria’s aches, chills and fever at least once a year and loses a week of field work when one of her children is ill. “They explained it wasn’t perfect, but I feel secure it will relieve the pain.”There is little escaping malaria -- “malungo” in the local Chichewa language -- especially during the five-month rainy season. Stagnant puddles, where mosquitoes breed, surround the homes of brick and thatch and line the dirt roads through tea plantations or fields of maize and sugar cane. In the village of Tomali, the nearest health clinic is a two-hour bike ride away. The longer it takes to get care, the more dangerous malaria can be. Teams from the clinic offer basic medical care during visits once or twice a month, bringing the malaria shot and other vaccines in portable coolers. Treating malaria takes up a good portion of their time during the rainy season, according to Daisy Chikonde, a local health worker.“If this vaccine works, it will reduce the burden,” she said.Resident Doriga Ephrem proudly said her 5-month-old daughter, Grace, didn’t cry when she got the malaria shot.When she heard about the vaccine, Ephrem said her first thought was “protection is here.” Health workers explained, however, that the vaccine is not meant to replace antimalarial drugs or the insecticide-treated bed net she unfolds every night as the sun sets and mosquitoes rise from the shadows. “We even take our evening meals inside the net to avoid mosquitoes,” she said.It took three decades of research to develop the new vaccine, which works against the most common and deadly of the five parasite species that cause malaria. The parasite’s complex life cycle is a huge challenge. It changes forms in different stages of infection and is far harder to target than germs.“We don’t have any vaccines against parasites in routine use. This is uncharted territory,” said Ashley Birkett, who directs PATH’s Malaria Vaccine Initiative, a nonprofit that helped drugmaker GlaxoSmithKline develop the shot, brand-named Mosquirix. The bite of an infected mosquito sends immature parasites called sporozoites into the bloodstream. If they reach the liver, they’ll mature and multiply before spewing back into the blood to cause malaria’s debilitating symptoms. At that point, treatment requires medicines that kill the parasites.Mosquirix uses a piece of the parasite — a protein found only on sporozoites’ surface — in hopes of blocking the liver stage of infection. When a vaccinated child is bitten, the immune system should recognize the parasite and start making antibodies against it.Scientists also are searching for next-generation alternatives. In the pipeline is an experimental vaccine made of whole malaria parasites dissected from mosquitoes’ salivary glands but weakened so they won’t make people sick. Sanaria Inc. has been testing its vaccine in adults, and is planning a large, late-stage study in Equatorial Guinea’s Bioko Island.And the U.S. National Institutes of Health soon will start initial tests of whether injecting people periodically with lab-made antibodies, rather than depending on the immune system to make them, could offer temporary protection during malaria season. Think of them as “potentially short-term vaccines,” NIH’s Dr. Robert Seder told a recent meeting of the American Society of Tropical Medicine and Hygiene.For now, only babies in parts of Malawi, Kenya and Ghana are eligible for the Mosquirix vaccine. After the vaccine was approved in 2015, the World Health Organization said it first wanted a pilot roll-out to see how well it worked in a few countries — in real-world conditions — before recommending that the vaccine be given more widely across Africa. “Everyone is looking forward to getting it,” said Temwa Mzengeza, who oversees Malawi’s vaccine programs. Those eager for the shots include her husband, whom she had to stop from trying to get them, she said.Mzengeza used to come down with malaria several times a year until she started following her own advice to sleep under a net every night. Unlike many other kinds of infections, people can get malaria repeatedly, building up only a partial immunity.In the pilot program that began last year, 360,000 children in the three countries are meant to be vaccinated annually. The first dose is given at about age 5 months and the final, fourth booster near the child’s second birthday.Experts say it is too early to know how well the vaccine is working. They’re watching for malaria deaths, severe infections and cases of meningitis, something reported during studies but not definitively linked to the vaccine.“To do something completely new for malaria is exciting,” said researcher Don Mathanga, who is leading the evaluation in Malawi. The rainy season has brought new challenges, making some rural roads impassable and complicating efforts to track down children due for a shot. So far in Malawi, the first dose reached about half of the children targeted, about 35,000. That dropped to 26,000 for the second dose and 20,000 for the third. That’s not surprising for a new vaccine, Mzengeza said. “It will pick up with time.”At the health clinic in Migowi in Malawi’s southern highlands, workers see signs of hope. Henry Kadzuwa explains the vaccine to mothers waiting at the clinic. He said there was a drop in malaria cases to 40 in the first five months of the program, compared to 78 in the same period in 2018.Even though he wishes his 3-year-old daughter, Angel, could receive the vaccine, “it’s protecting my community. It also makes my work easier,” Kadzuwa said. The Migowi area has one of the country’s highest rates of malaria, and a worn paper register in the clinic’s laboratory lists scores of cases.At the clinic, Agnes Ngubale said she had malaria several years ago and wants to protect her 6-month-old daughter, Lydia, from the disease.“I want her to be healthy and free,” she said. “I want her to be a doctor.”And she has memorized the time for Lydia’s second dose: “Next month, same date.”___Neergaard reported from Washington.___The Associated Press Health and Science Department receives 7200

An armed gang who kidnapped an American tourist and her driver at gunpoint from a Ugandan national park have made frequent demands for a 0,000 ransom, which will not be paid, Ugandan police said Thursday."They (the abductors) continue to use cell phones of the victims to call the lodge they were staying asking for 0,000 ransom, which we will not offer," Uganda Deputy Police Spokeswoman Polly Namaye said.Police say they will intensify the hunt for the abductors instead of offering the ransom and have closed borders near where the tourist and her Ugandan driver were seized during an evening game drive on Tuesday at Queen Elizabeth National Park."We want to inform the public and all visitors in the country that the joint security teams have cut off all exit areas on the border between Uganda and the DRC in search for the victims," Namaye said.Namaye said the police and other security agencies were working with the American embassy in Kampala, Uganda's capital to rescue the hostages who police believe are still within the country.The US State Department spokesperson said its security forces were responding to the incident, but gave no further details."We are aware of reports of a US citizen kidnapped in Uganda. Security forces are responding to the incident. We have no further information to offer at this time," the spokesperson said.The American citizen was 1395

Actress Jessica Biel is speaking out about her meetings with California lawmakers and anti-vaccination advocate Robert F. Kennedy Jr. to discuss a controversial vaccine bill."I am not against vaccinations," Biel wrote in an Instagram post on Thursday. "I support children getting vaccinations and I also support families having the right to make educated medical decisions for their children alongside their physicians." 432

All states holding presidential primaries next Tuesday say voting will take place as scheduled, despite the novel coronavirus pandemic.In a 152