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The excitement of two COVID-19 vaccines with more than 90 percent efficacy is undeniable.In November, both Pfizer and Moderna announced its scientists had developed vaccines with efficacy at or near 95 percent, but scientists are warning these vaccines are not the "silver bullet" to ending the pandemic.“We don’t want to give the public the impression that there’s an emergency use authorization and these vaccines become available in a small amount in December and we can go back to our pre-pandemic behavior,” said William Moss, executive director of the International Vaccine Access Center at Johns Hopkins.In June, the FDA released its vaccine guidelines, saying it would consider emergency use authorization for any vaccine testing with at least 50 percent effectiveness, so there is a reason for celebration, according to Moss, but only after certain questions about the vaccine are answered.Dr. Anthony Fauci has said the initial vaccines will prevent symptoms in those who become infected, rather than kill the virus itself. Moss says that means immunized people might be able to spread COVID-19 to others.He also wonders how long immunization will last. One year? Three years? Will booster doses be needed? They're all careful considerations that will only emerge once one is put into play, according to Moss.“It’s obviously tragic that the [COVID] cases are occurring that quickly, but it does help a vaccine trial because otherwise you just have to wait that much longer for samples to come in,” said Moss.The vaccine process has innovated how scientists and researchers approach these types of situations, however, according to Moss.In traditional vaccines, a small dose of the virus is injected into the body so the immune system can create antibodies. In the COVID-19 vaccine, though, both Moderna and Pfizer have used what is called messenger RNA (mRNA) where the virus’ genetic code is injected into the body so it can instruct cells on what antibodies to produce. Scientists say this way is faster, safer, and can create a stronger immune response as people are not exposed to the virus.“I suspect that if this all goes well and these vaccines are safe and continue to demonstrate 90 to 95 percent efficacy, we’re going to see other vaccines of a similar type,” said Moss. 2298

The family of a Rochester, New York man killed during an encounter with police earlier this year, says officers' use of force led to his death as he suffered a mental health crisis.Following the release of the arrest video by Prude's family on Wednesday, protesters called for the city council to pass legislation that would forbid police officers from responding to mental health crises.On March 23, police encountered Daniel Prude in a Rochester street, naked, bleeding and unarmed. According to ABC News, he had been brought to the hospital earlier that evening after experiencing suicidal thoughts and had been subsequently released.Prude initially complied, and officers placed him in handcuffs.With the coronavirus pandemic in its infancy, officers then chose to place a spit hood over Prude's head. The hood appears to agitate Prude, and he asked officers to remove it.Moments later, Prude attempted to stand up, and officers wrestled him back to the ground.Video shows officers pressing Prude's face into the pavement for two minutes.It was then that police realized that Prude had stopped responding. Officers administered CPR, and he was rushed to the hospital.On March 30, Prude died when he was taken off life support."I tell this particular officer that comes to my door (prior to the incident), don't you kill my damn brother," Prude's brother Joe said on Wednesday. "Not even 15 minutes later, he comes back and tells me my brother is dead. You put a bag over his head — what did you put a bag over his head for?"An autopsy from the Monroe County Medical Examiner found that Prude died from complications of asphyxia from physical restraint. He also may have had PCP in his system.The Rochester Police Chief said he ordered criminal and internal investigations following the incident. The case was sent to the New York Attorney General's office, as required by state law when investigating in-custody deaths.None of the officers involved in the incident have been suspended. Protesters in Rochester Wednesday night called for the removal of the officers from the department."A naked and defenseless man lynched and we need to think about that in this moment," activist Stanley Martin said. "We have no excuse. This happened under the watch of the city." 2276

The E.W. Scripps Company is a partner with The Associated Press and has been following guidance from their election desk on 2020 race updates.Below is the AP's explanation as to why they have not declared a winner in Georgia and why they declared Democratic presidential nominee Joe Biden the winner in Michigan and Wisconsin.WISCONSINThe AP called Wisconsin for Democrat Joe Biden after election officials in the state said all outstanding ballots had been counted, except for a few hundred in one township and an expected small number of provisional ballots. Trump’s campaign has requested a recount. Statewide recounts in Wisconsin have historically changed the vote tally by only a few hundred votes; Biden leads by .624 percentage points out of nearly 3.3 million ballots counted.“Despite ridiculous public polling used as a voter suppression tactic, Wisconsin has been a razor-thin race as we always knew that it would be," Trump campaign manager Bill Stepien said in a statement. "There have been reports of irregularities in several Wisconsin counties which raise serious doubts about the validity of the results. The President is well within the threshold to request a recount and we will immediately do so.”--MICHIGANThe Associated Press declared Biden the winner of Michigan at 5:56 p.m. EST Wednesday after conducting an analysis of votes and remaining ballots left to be counted. It showed there were not enough votes left in Republican-leaning areas for Trump to catch Biden’s lead. Biden had a 70,000-vote lead on Wednesday evening, a margin over Trump of about 1.3 percentage points.It's the third state President Donald Trump carried in 2016 that the former vice president has flipped, narrowing Trump’s path to reelection.On Thursday, a Michigan judge dismissed the Trump campaign's lawsuit over whether enough GOP challengers had access to the handling of absentee ballots, the AP reported.--GEORGIAThe Associated Press has not declared a winner in Georgia’s presidential contest because the race between President Donald Trump and Democratic nominee Joe Biden is too early to call, with outstanding ballots left to be counted in counties where Biden has performed well. Early Wednesday, Trump prematurely claimed he carried Georgia. But the race is too early to call because an estimated 4% of the vote still remains to be counted. That includes mailed ballots from population-dense counties in the Atlanta metro region that lean Democratic. Biden is overperforming Hillary Clinton’s 2016 showing in those counties — including in their more upscale suburban reaches. 2594

The combined jackpot between Powerball and Mega Millions this week is now more than billion.Tuesday's Mega Millions jackpot, which is now at 7 million, is the largest this lottery has ever seen.The drawing for the record-breaking Mega Millions is at 11 p.m. Eastern today.Wednesday's Powerball drawing is now at 5 million.LIST:?Luckiest lottery numbers: Powerball, Mega Millions most common picksTake a look at the list below for the largest jackpots in U.S. history, according to the Arizona Lottery: 533

The Food and Drug Administration’s Vaccines and Related Biological Products Advisory Committee has endorsed Pfizer’s coronavirus vaccine, in a major step toward an epic vaccination campaign that could finally conquer the outbreak. The group, in a 17-4 vote with one abstention, concluded that the shot appears safe and effective against the coronavirus in people 16 and older.The Food and Drug Administration is expected to follow the recommendation issued Thursday by its expert advisers. A final FDA decision is expected within days. The vaccine had already been authorization by officials in Canada and the UK.An emergency use authorization allows practitioners to administer a vaccine despite it not gaining full FDA approval. The EUA means that the vaccine is allowed to be used in non-clinical settings, which would allow Americans not in a trial or hospital setting to get the vaccine.Millions of shots would then ship to begin vaccinating health care workers and nursing home residents, but the Centers for Disease Control and Prevention will need to formally recommend the vaccine before health care officials can begin distributing the shots.Once it is authorized, it is expected that several million doses of the vaccine will immediately begin being distributed throughout the US to high-risk individuals. The first group of those expected to be inoculated includes health care workers and those who live or work in assisted living facilities.“The FDA recognizes that transparency and dialogue are critical for the public to have confidence in COVID-19 vaccines. I want to assure the American people that the FDA’s process and evaluation of the data for a potential COVID-19 vaccine will be as open and transparent as possible,” said FDA Commissioner Stephen M. Hahn, M.D. “The FDA has been preparing for the review of EUAs for COVID-19 vaccines for several months and stands ready to do so as soon as a EUA request is submitted. While we cannot predict how long the FDA’s review will take, the FDA will review the request as expeditiously as possible, while still doing so in a thorough and science-based manner, so that we can help make available a vaccine that the American people deserve as soon as possible.”Pfizer says that the vaccine is showing a 95% efficacy against coronavirus infection. It is one of two vaccines that could be approved by the FDA in the next few weeks. Moderna also has a vaccine candidate that is showing the efficacy of 95%.“Our work to deliver a safe and effective vaccine has never been more urgent, as we continue to see an alarming rise in the number of cases of COVID-19 globally. Filing in the U.S. represents a critical milestone in our journey to deliver a COVID-19 vaccine to the world and we now have a more complete picture of both the efficacy and safety profile of our vaccine, giving us confidence in its potential,” said Dr. Albert Bourla, Pfizer Chairman and CEO. “We look forward to the upcoming Vaccines and Related Biological Products Advisory Committee discussion and continue to work closely with the FDA and regulatory authorities worldwide to secure authorization of our vaccine candidate as quickly as possible.”One concern over the Pfizer vaccine is possible side effects on those prone to allergic reactions. The UK’s National Health Service is advising those prone to allergic reactions to not take the Pfizer vaccine as it investigates two health care workers having apparent reactions after receiving the vaccine.Once given authorization, officials will be forced to confront two challenges: Public confidence in the vaccine and distribution. Both the Moderna and Pfizer vaccines are required to be refrigerated until use, complicating distribution methods.Also, polls are showing that a significant number of Americans are hesitant to take the vaccine. Public health experts say getting the vast majority of Americans immunized is important in order to reach herd immunity against the virus and to allow for normalcy to return to the US.In addition to a number of public health experts saying they’ll get the vaccine as a way to instill trust, former Presidents Bill Clinton, George W. Bush, and Barack Obama said they would publicly take the vaccine in order to instill faith in the shot.Widespread access to the general public is not expected until the spring. 4342

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