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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
COPENHAGEN, June 7 (Xinhua) -- The outbreak of infections caused by E. coli bacteria may be over in Denmark as no new cases have been reported here since Friday.According to Denmark's National Serum Institute (NSI), there are 18 confirmed cases of severe intestinal infection caused by exposure to the bacteria as of Monday. No new infections have been reported since Friday, it added.The confirmed cases are said to consist of 10 men and 8 women aged between 23 and 81 years of age. Seven show symptoms of kidney failure which is associated with advanced stages of the infection.All but one are believed to have contracted the infection while traveling in northern Germany, where the outbreak started, the NSI said.So far, the E. coli infection has claimed 21 lives in Germany, which reports over 2,100 confirmed and suspected cases. It has also spread to 12 countries according to the World Health Organization (WHO)."This particular strain of E.coli has been identified in some people sporadically in the past, but it has not been known to have been associated with outbreaks in the past," a WHO spokesperson said Friday, adding it was a "very, very rare strain."Health authorities in Germany now suspect bean sprouts as the source of contamination in this outbreak, although this is yet to be confirmed.Dr Kaare Moelbak, an epidemiologist at NSI told Danish media Sunday that bean sprouts were a "very likely" source of contamination.Cucumbers were initially suspected and Denmark's food authority continues to warn against eating raw tomato, cucumber or lettuce from Germany until the source is established.Children are normally most vulnerable to E. coli infection but most of those infected in this outbreak are above the age of 20 years, Moelbak told Xinhua last week.He said children are likely less affected by this outbreak as they usually eat fewer salads than adults.In Germany, it is mostly women who have been affected by the infection. Moelbak explained the skew in infections saying women tend to choose to eat more vegetables than men, in comments made to Danish media Thursday.
BEIJING, Sept. 6 (Xinhuanet) -- A short-term memory loss may suggest the Alzheimer's disease, according to a new study made by Spanish researchers.The finding was published on Monday, in Archives of General Psychiatry, an American Medical Association journal.The researchers gathered data of 116 people with mild cognitive impairment (MCI) who developed Alzheimer's disease within two years, 204 patients with the condition who didn't develop Alzheimer's and 197 people with no cognitive problems.Mild cognitive impairment is usually marked by difficulties with short-term memory, such as losing your train of thought repeatedly or having trouble remembering what you did yesterday, according to the study.After assessing them by biomarker tests and cognitive measures, the researcher found the cognitive markers can forecast the variance."Remarkably, they accounted for nearly 50% of the predictive variance," said Dr. Gomar of Centro de Investigation Biomedica en Red de Salud Mental, Barcelona, who led the research.Mild cognitive impairment at the start of the study was a stronger predictor of Alzheimer's than most biomarkers, the researchers concluded.
KIEV, Aug. 2 (Xinhua) -- Ukraine's regional health authority declared Tuesday a cholera epidemic in the eastern region of Donetsk had ended.All 26 people who had been treated for the disease had been discharged from hospital, the press-service of the Donetsk Regional Sanitary and Epidemiological Service said on its official website.As of this week, no new cases had been registered, the statement said.The cholera outbreak hit eastern Ukraine in late May. The disease can cause rapid dehydration and death.The outbreak was believed to be associated with fish and drinking water supplies from the Sea of Azov.
SAN FRANCISCO, July 29 (Xinhua) -- Apple has ousted Nokia as the world's largest smartphone maker as global mobile phone market grew more than 11.3 percent in the second quarter of 2011, according to two separate market research studies.After becoming the largest smartphone vendor in terms of revenue and profits, Apple has become the world's largest smartphone vendor by volume with 18.5 percent market share, said the latest research from Strategy Analytics released on Friday.The Cupertino, California-based company sold 20.3 million iPhones in the second quarter,up 142 percent compared with the same period a year earlier.Samsung's shipments of 19.2 million units grew a huge 520 percent year over year, accounting for 17.5 percent global smartphone market share in the second quarter of 2011.Apple and Samsung overtook long-time volume leader Nokia for the two spots. The Finnish mobile phone giant accounted for 15.2 percent of global smartphone market share in the last quarter, which is less than half of what it was just one year earlier.In the second quarter of 2010, Nokia was the No.1 smartphone maker by volume in the world with 38.1 percent of market share. The industry is now waiting Nokia's pending transition to Windows Phone 7.According to a separate report by International Data Corporation (IDC) released on Thursday, the worldwide mobile phone market grew by 11.3 percent year over year in the second quarter of 2011 despite a decline of the feature phone market for the first time in almost two years.The feature phone market was down by 4 percent in the last quarter, said the IDC Worldwide Mobile Phone Tracker report. It noted that the decline in shipments was mainly in economically mature regions, such as the United States, Japan and Western Europe, as users making rapid transition to smartphones.The shrinking feature phone market had a great impact on some of the world's largest suppliers of mobile phones, such as Nokia, which is losing share in the feature phone category to low-cost suppliers, said the report.For the overall market, global mobile phone vendors shipped 365. 4 million units in the second quarter, compared to 328.4 million units in the same period last year, with Nokia still holding the top spot with a market share of 24.2 percent, followed by Samsung, LG Electronics, Apple and ZTE.But the 11.3 percent growth was lower than IDC's forecast for the quarter and also below the 16.8 percent growth in the first quarter of 2011.IDC said the feature phone forecast isn't expected to be any rosier in the future and the shipment growth of feature phones won 't exceed 1.1 percent in the coming years.