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BEIJING, Oct. 18 (Xinhuanet) -- Autism can likely develop when low birth weight babies are combined with other factors such as environment and genetic predisposition, new research suggests.Researchers from the University of Pennsylvania School of Nursing and School of Medicine identified 1,105 children who weighed less than 2,000 grams at birth between Oct. 1, 1984, and July 3, 1989.Sixteen years later, researchers were able to reach 623 of those children, and used a questionnaire to screen them for autism spectrum disorders.When 189 of the children turned 21 years old, 60 percent of those who screened positive for an autism spectrum disorder, and 24 percent of those who screened negative with the condition. All in all, the rate of autism spectrum disorders among the study participants with low birth weights was five times higher than the general.Autism spectrum disorder makes people have difficulty communicating, difficulty interacting in social situations, and restrictive or repetitive interests, said study co-author Jennifer Pinto-Martin, a researcher in the University.Those with mild autism spectrum disorders, "may only want to talk about one subject," Pinto-Martin said. "They're perfectly functional. They can go to college. They can hold a job." Premature babies are often born with low birth weights, though full-term babies can also have the condition. The research suggests a need not only for better prenatal care to reduce the number of premature babies, but also a need for early diagnosis and intervention for people with autism.
SAN FRANCISCO, Dec. 8 (Xinhua) -- Apple on Thursday released iTunes Rewind 2011 and App Store Rewind 2011, its annual lists of top selling music, TV shows, movies and apps for the year.Apple picks Instagram as "iPhone App of the Year." Instagram is a free photo sharing application which enables users to confine photos into a square shape in an homage to both Kodak Instamatic and Polaroid cameras, and share them on a variety of social networking services.Photo editing software Snapseed is picked as "iPad App of the Year.""Angry Birds" was the top paid iPhone and iPad app for 2011. Its spinoffs, "Angry Birds Seasons" and "Angry Birds Rio," also make to the top 10 lists.ITunes' best-selling movie is "The Social Network" and "Doctor Who" is the best-selling season TV series. An episode of "Walking Dead" is the best-selling TV episode.The best-selling fiction book was "The Help." "Steve Jobs," the only official biography of the late Apple co-founder, was the best- selling non-fiction book.In iTunes Rewind 2011, British singer Adele sweeps three major music category, named for top-selling song (Rolling in the Deep), top-selling album (21) and iTunes Artist of the year for 2011.ITunes also picked Foo Fighter's "Wasting Light" as album of the year, "Pumped up Kicks" by Foster the People as song of the year, and Nicki Minaj as its breakthrough artist of the year.First launched as iTunes Music Store in 2003, the Apple online digital media store became the largest music seller in the United States in 2008. Last February, Apple announced that more than 10 billion songs have been sold in iTunes Store. In 2008, Apple said over 200 million TV episodes had been sold.The Apple App Store was initially released in July 2008. According to Apple's data, more than 18 billion apps have been downloaded as of Oct. 4.

BEIJING, Oct. 8 (Xinhua) -- Authorities hope to innovate social management by restructuring its governmental organ, an official said in an interview with Xinhua and the People's Daily on Saturday.The organ, the Central Committee for Comprehensive Social Management, was renamed and restructured in a meeting last month from the previous Central Committee for Comprehensive Management of Public Security.With 11 more departments than the previous one, the new committee, with 51 departments, is expected to strengthen and innovate social management so as to build a harmonious, stable society, an official from the general office of the committee said.The official said the renaming and restructuring of the committee came as the former's concepts, mechanisms and measures fell behind China's fast social and economic development after its 20 years of existence.The official said the new committee will primarily address some major issues that could threaten social harmony and stability, such as criminal gangs and juvenile delinquency, while enacting laws and regulations for social management.
ALMATY, Nov. 4 (Xinhua) -- Kazakhstan's Center for Prevention and Control of AIDS said Friday that the country had 17,266 registered HIV carriers as of Oct. 1,compared with 15,908 as of Feb. 1, 2010.Of the HIV-positive people, 1,432 were diagnosed with AIDS while 1,110 people carrying the virus AIDS have died, the center said.Last year, it said, a total of 1,969 new HIV cases were reported in the country.
WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.
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