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HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.
TEHRAN, June 15 (Xinhua) -- Iran puts the Rasad (surveillance) satellite in the orbit on Wednesday, the state IRIB TV website reported.The Rasad satellite will render images to the country, said the report.All the procedure of designing, construction, testing and preparations to launch the satellite have been conducted domestically by Iranian experts, according to IRIB.The Rasad, weighs 15.3 kilograms and has been designed to be launched at 260 kilometers above the earth, said IRIB, adding that it will circle the earth 15 times in 24 hours.

WASHINGTON, Aug. 2 (Xinhua) -- Breastfeeding protects against childhood obesity, but less than 4 percent of U.S. hospitals provide the full range of support mothers need for breastfeeding, according to a report issued by the Centers for Disease Control and Prevention Tuesday.Improving rates of breastfeeding by providing better hospital support to mothers and babies is an important strategy to improve children's health, including a reduced risk of childhood obesity, the monthly Vital Signs report said."Hospitals play a vital role in supporting a mother to be able to breastfeed," it said."Those first few hours and days that a mom and her baby spend learning to breastfeed are critical. Hospitals need to better support breastfeeding, as this is one of the most important things a mother can do for her newborn. Breastfeeding helps babies grow up healthy and reduces health care costs," it added.The report found only 14 percent of hospitals have a written and model breastfeeding policy.It also found in nearly 80 percent of hospitals, healthy breastfeeding infants are given formula when it is not medically necessary, a practice that makes it much harder for mothers and babies to learn how to breastfeed and continue breastfeeding at home.Additionally, only one-third of hospitals practise rooming in, which helps mothers and babies learn to breastfeed by allowing frequent chances to breastfeed.Finally, the report found in nearly 75 percent of hospitals, mothers and babies don't get the support they need when they leave hospitals, including a follow-up visit, a phone call from hospital staff and referrals to lactation consultants, and other important support systems in their communities.
WASHINGTON, Aug. 24 (Xinhua) -- Online search engine Google Inc. has agreed to pay 500 million U.S. dollars to settle claims that it allowed online Canadian pharmacies to place advertisements targeting consumers in the United States, U.S. Justice Department announced Wednesday.The settlement, one of the largest ever in the United States, represents the gross revenue received by Google as a result of Canadian pharmacies advertising through Google's AdWords program, plus gross revenue made by Canadian pharmacies from their sales to U.S. consumers.The advertisements led to illegal imports of prescription drugs into the country, the Justice Department said.The shipment of prescription drugs from pharmacies outside the United States to customers in the United States typically violates the Federal Food, Drug and Cosmetic Act and in the case of controlled prescription drugs, the Controlled Substances Act.Google was aware as early as 2003, that generally, it was illegal for pharmacies to ship controlled and non-controlled prescription drugs into the United States from Canada."The Department of Justice will continue to hold accountable companies who in their bid for profits violate federal law and put at risk the health and safety of American consumers," Deputy Attorney General James Cole said in a statement."This settlement ensures that Google will reform its improper advertising practices with regard to these pharmacies while paying one of the largest financial forfeiture penalties in history," he said.Google had previously set aside that amount for a possible settlement over its advertising practices, according to a regulatory filing in May.
BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene. In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma. More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.
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