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BEIJING, July 1 (Xinhuanet) -- China must adopt a holistic approach to addressing food safety challenges connected to the risk of contracting infectious diseases from contact with animals, the World Health Organization (WHO) has said. Peter Ben Embarek, food safety officer at WHO's China office, said the country faces risks connected to the need to produce more meat, eggs and milk to feed its growing population. He said the increased production will ramp up the risk of people being infected by food-borne diseases because of poor slaughtering oversight and the absence of proper surveillance and inspection systems. About 50 percent of pigs in China are slaughtered outside of formal facilities without the inspection of veterinarians or food safety officers. He said poorly trained producers have little or no awareness of food safety or the risk of animal diseases being passed on to humans. Such an environment could lead to the emergence of a new pandemic of influenza. During the past 60 years, 30 percent of the 335 new infectious diseases worldwide were transmitted through food, he said. Yet in many parts of China, public awareness remains low about such things. Xu Aixiang, a 35-year-old resident of Rizhao city in Shandong province, prefers to buy live poultry at local markets. Like many of her neighbors, she takes the chickens she buys home to slaughter them. "I get fresher chickens that are better quality this way," she said. "When vendors sell slaughtered chickens, the meat is no longer fresh and may have had water injected into it to make it heavier." But Ben Embarek cautioned that such live-animal markets are high-risk places for the exchange of viruses and diseases between animals and humans. He said simple and cost-effective measures can be taken to improve such markets' hygiene standards, such as the installation of separate areas to keep live poultry away from customers as well as improving air flow and waste management. Several UN agencies, including the WHO and the Food and Agriculture Organization, called on China to adopt an integrated approach to preventing emerging epidemic diseases and maintaining ecosystem integrity at an event themed "One Health" that convened on Wednesday in Beijing. At the gathering, representatives from the Ministry of Health, the Ministry of Agriculture and the Chinese Center for Disease Control and Prevention shared experiences from efforts to mitigate the H5N1 and H1N1 influenza outbreaks in China and said they were committed to working together in the future. Su Jingliang, an associate professor of preventive veterinary medicine at China Agricultural University, said his lab had detected the outbreak of a new type of flavivirus in ducks that led to a significant fall in egg production at farms in Beijing as well as in Hebei, Jiangxi and Shandong provinces. The pandemic was brought under control in March. No cases of humans contracting the disease have been reported so far but Su said he was concerned about the possibility of farmers becoming infected through close contact and long exposure to sick ducks. He said precautionary measures should be taken in cooperation with the Ministry of Health and other government agencies and checks should be run on people who are at high risk. Xu Wei contributed to this story.
BEIJING, Sept. 8 (Xinhuanet) -- Middle-aged white women drinking alcohol moderately are more likely to stay healthy than nondrinkers, according to a new study from Harvard.The study has followed about 14,000 mostly white women since 1976.As a result, compared with teetotalers, those who had 3 to 15 alcoholic drinks weekly in their late 50s were 28 percent higher of being free from physical disability, chronic illness, mental health problems, and cognitive decline at the age of 70.Even having just one or two drinks per week increased a woman's odds of good health by 11 percent.However, women should be aware that even moderate drinking has been linked to an increased risk of breast cancer, said Qi Sun, M.D., a lead author of the study and a nutrition researcher at the Harvard School of Public Health.These findings don't necessarily apply to men or to nonwhite women. But they reinforced the evidence for the health benefits of moderate drinking.
LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).
WASHINGTON, June 8 (Xinhua) -- Hundreds of small genetic variations are associated with autism spectrum disorders, including an area of DNA that may be a key to understanding why humans are social animals, according to a multi-site collaborative study led by researchers at Yale University.To be published Thursday in the journal Neuron, the study reinforces the theory that autism, a disorder that develops in early childhood involving impairments in social interaction, language deficits and distinctive behaviors, is not caused by one or two major genetic defects, but by many small variations, each associated with a small percentage of cases.The study looked at more than 1,000 families in which there was a single child with an autism spectrum disorder, an unaffected sibling and unaffected parents. The team compared individuals with autism to their siblings to determine what types of genetic changes distinguished the affected child from the unaffected child.One of the most intriguing of these findings points to the same small section of the genome that causes Williams syndrome -- a developmental disorder marked by high sociability and an unusual aptitude for music.In autism, there is an increase in the chromosomal material, an extra copy of this region, and in Williams syndrome, there's a loss of that same material," said lead author Matthew State. "What makes this observation particularly interesting is that Williams syndrome is known for a personality type that is highly empathetic, social, and sensitive to the emotional state of others. Individuals with autism often have difficulties in the opposite direction. This suggests that there is an important key in that region to understanding the nature of the social brain."State and his team also found about 30 other regions in the genome that are very likely contributing to autism and are focused on about six of those regions that showed the strongest evidence."We're now moving on to a second phase of the study looking at an additional 1,600 families and should be able to identify multiple new regions that are strongly implicated in autism," he said.
LOS ANGELES, June 3 (Xinhua) -- Eating earth may protect the stomach against toxins, parasites and pathogens, a new study suggests.To examine the possible benefits from eating earth, researchers at Cornell University analyzed reports from missionaries, plantation doctors, explorers, and anthropologists to put together a database of more than 480 cultural accounts of geophagy -- the eating of earth.The database includes as many details as possible about the circumstances under which earth was consumed, and by whom. The researchers could then use patterns in the data to evaluate each potential explanation.Studies in the database indicate that geophagy is common even when food is plentiful. Moreover, when people eat dirt they tend to eat only small quantities that are unlikely to fill an empty stomach.The database shows that geophagy is documented most commonly in women in the early stages of pregnancy and in pre-adolescent children. Both categories of people are especially sensitive to parasites and pathogens, according to the researchers.In addition, geophagy is most common in tropical climates where foodborne microbes are abundant. Finally, the database shows that people often eat earth during episodes of gastrointestinal stress.It's unlikely the intestinal problems are caused by the dirt itself because the type of clay people usually eat comes from deep in the ground, where pathogens and parasites are unlikely to contaminate it. Plus, people usually boil the clay before eating it.More study would be helpful to confirm the protection hypothesis, the researchers say, but the available data at this point clearly support it over the other explanations for eating earth."We hope this paper stimulates (more) research," said Sera Young, a researcher at Cornell University and the study's lead author. "More importantly, we hope readers agree that it is time to stop regarding geophagy as a bizarre, non-adaptive gustatory mistake.""With these data, it is clear that geophagy is a widespread behavior in humans ...that occurs during both vulnerable life stages and when facing ecological conditions that require protection."The study is appearing in the June issue of The Quarterly Review of Biology.