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CLEVELAND — Scientists at the Cleveland Clinic Lerner Research Institute have successfully reversed Alzheimer's disease in mice.According to a news release, the researchers reversed the formation of harmful plaque in the mice's brains by gradually reducing an enzyme called BACE1, improving their mental function.“To our knowledge, this is the first observation of such a dramatic reversal of amyloid deposition in any study of Alzheimer’s disease mouse models,” says Riqiang Yan, one of the scientists on the team. The study raises hopes that drugs aimed at this same enzyme will soon be able to treat Alzheimer's disease in humans. You can read the full study in the Journal of Experimental Medicine here. 735
CORONADO, Calif. (KGTV) — Hotel Del's most notable resident may be the special guest of an event at the Coronado landmark this month.On Oct. 12, medium James Van Praagh will host a séance at the Hotel Del Coronado in which he will try to connect with the hotel's permanent guest, Kate Morgan, in addition to any others significant to those in attendance.But Morgan isn't the only thing drawing the medium to the iconic hotel. Van Praagh's first visit to the location left quite the impression.RELATED: Discovery the Star of India's ghostly past on special October tours"Well besides being gorgeous and completely unique, it’s extremely haunted," Van Praagh said in a release. "The lobby area has very heavy imprints of spirit. 10 years ago when I visited Hotel Del Coronado for the first time, I didn’t know it’s history. As soon as I walked in, I saw women in Victorian dresses all over the lobby."Morgan is known for her presence at the Hotel Del. According to the hotel, Morgan checked into the hotel alone under the name "Lottie A Bernard" from Detroit. Five days later, she was found dead on a hotel staircase leading to the beach.The San Diego County coroner determined she had died from a self-inflicted gunshot wound to the head.RELATED: Halloween family fun, haunted houses, and parties in San DiegoOver time, guests say they have seen Morgan, felt breezes come from nowhere, and seen televisions turn on and off by themselves.But in order to have a successful reading, Van Praagh says he's going into the experience without any prior knowledge of Morgan."I don’t know enough about Kate to know if we’ve met. She might have been part of the crowd of spirits I saw hanging out in the hotel lobby the first time I visited the Del," Van Praagh said. "I don’t want to research her, because I want to hold the séance in October with a totally open mind so she can come through clearly."Tickets for the VIP seance are extremely limited and will cost 9 to join the group. Van Praagh is a New York Times best-selling author and known around the world for his readings. He's appeared on national television as well, including appearances on Oprah, Larry King, Dr. Phil, and more. 2225

COSTA MESA, Calif. (AP) — A judge has put on hold a U.S. plan to quarantine up to 50 people infected with a new virus from China in a Southern California city. Costa Mesa officials asked for a court to intervene Friday after learning that federal authorities planned to move patients to facility in the city as early as Sunday. They said they were not included in the planning effort and wanted to know how the local community would be protected from the possible spread of the virus that has spread globally. The judge has issued a temporary restraining order and has scheduled a hearing for Monday. 609
COLORADO SPRINGS, Colo. (KMGH) – Colorado Springs police say a woman has repeatedly done her businesses in people’s yards over the past several weeks.A witness snapped photos of the female runner, who has apparently been caught treating people’s yards as toilets on several occasions since July.The latest instance happened at a house in the Pine Creek neighborhood, near Briargate Parkway. A woman there told officers her children spotted the woman right in the middle of things. 498
CORONADO, Calif. (KGTV) - Two political opponents running against each other for the Coronado City Council have formed a special bond which they refuse to let be ruined by the campaign."She's my opponent, but I love my opponent. She's like a mother to me," says candidate Derik Mundt about fellow candidate Mary Sikes.The two have been friendly since Mundt was a teenager volunteering for the Coronado Film Festival, which Sikes ran until her retirement this year. However, they did not realize when they decided to run that they would be doing so against the other."She's a saint," Mundt said. "When you're sick, she brings you soup. That's what she does. She's like the mom of Coronado."Mundt recently found out how true those sentiments were. Last week he began feeling sick, with a fever topping 102. It turned out to be a case of the flu so bad, he was taken to the emergency room. Mundt ended up hospitalized for five days. One of his first calls was to Sikes."My first thought was just to get there and just be there," Sikes said.Sikes visited Mundt in the hospital each day and stayed in touch with his mother to update her on his status. When it became clear he would not be released in time for the final candidate forum in the race, Sikes made a surprising offer."You've come this far and it's so close," she told Mundt. "I'll give your speech tomorrow because I know it by heart."When Mundt was finally released from the hospital Monday afternoon, it was Sikes who came to pick him up and drive him home."Dirty politics don't belong in politics," Mundt says. "This is how it's supposed to be."There are six total candidates running for two open seats on the Coronado City Council, meaning it's possible Mundt and Sikes could both win or lose."What we've been saying to each other all along is if at least one of us gets on, we know that this town will be in good hands," Sikes said. 1917
来源:资阳报