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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
SAN FRANCISCO, March 29 (Xinhua) -- Amazon.com Inc. on Tuesday announced the launch of an on-line music storage service,which enables users to store digital music in the cloud and access it from computers and devices running Google's Android operating system.The new service, called "Cloud Drive," offered customers five gigabytes of free storage on Amazon Web servers for all kinds of digital files, including music, photos, videos and documents. For paid plans, users can purchase storage space starting at 20 U.S. dollars a year for 20 gigabytes.The on-line retailer also launched "Cloud Player for Web" and " Cloud Player for Android." The former allows users to get the media files they stored on Amazon's servers from a Web browser on a Mac or PC. The latter lets users play music they have uploaded on Cloud Drive, computers or a smartphone that runs Android operating system.Analysts said Amazon is stepping up its rivalries with Apple and Google. Both companies are also working on similar services, allowing users to store their music on-line and access it from any compatible device.Media reports said that Apple was pushing hard to launch a digital music locker service in April. Google was also reported to be testing its own digital locker service but it still needs to make agreements with major music labels.

BEIJING, Feb. 9 (Xinhua) -- The Chinese currency, or the yuan, rose to a new high of 6.585 against the U.S. dollar Wednesday, according to the China Foreign Exchange Trading System.The central parity rate of the RMB, or the yuan, was 10 basis points higher than the previous record of 6.586 set on Feb. 1, the previous trading day.The yuan appreciated 3.6 percent last year, but some analysts predict it could rise further against the dollar this year as the People's Bank of China (PBOC), the central bank, attempts to cool accelerating inflation.The PBOC announced Tuesday it would raise the benchmark one-year borrowing and lending rates by 25 basis points from Wednesday.On China's foreign exchange spot market, the yuan can rise or fall 0.5 percent from the central parity rate each trading day.The central parity rate of the RMB against the U.S. dollar is based on a weighted average of prices before the opening of the market each business day.
WASHINGTON, March 30 (Xinhua) -- A trace amount of radioactive iodine has been found in a sample of milk from the west state of Washington, the U.S. Environmental Protection Agency and the Food and Drug Administration (FDA) said Wednesday.According to a joint statement from the two agencies, results from a screening sample taken March 25 from Washington detected 0.8 pCi/L of iodine-131, which is more than 5,000 times lower than the Derived Intervention Level set by the FDA.These types of findings are to be expected in the coming days and are far below levels of public health concern, including for infants and children, the statement said.Iodine-131 has a very short half-life of approximately eight days, and the level detected in milk and milk products is therefore expected to drop relatively quickly."Radiation is all around us in our daily lives, and these findings are a minuscule amount compared to what people experience every day. For example, a person would be exposed to low levels of radiation on a round trip cross country flight, watching television, and even from construction materials," said Patricia Hansen, an FDA senior scientist.
BEIJING, Feb. 8 (Xinhuanet) -- China's railroads and highways will see their busiest day of the Spring Festival holiday on Tuesday when the number of travelers returning to major cities hits its peak, just as a cold snap sweeps across much of the country, the ministries of railways and transport said on Monday.The Ministry of Railways said on its website that there had been a sharp rise in the number of travelers leaving smaller cities on Monday bound for such places as Beijing, Shanghai and Guangzhou.The ministry said the number of people on the move on Tuesday is likely to make the day the Spring Festival travel peak.The nation's roads are also likely to be at their Spring Festival maximum on Tuesday and Wednesday, the Ministry of Transport reported on Monday on its official website.The National Meteorological Center (NMC) added on Monday that a moderate cold snap was expected on Tuesday, causing temperatures to fall by between four and six degrees in most parts of China.The weather pattern will bring widespread rain and snow to the southern part of China from Wednesday to Friday, the NMC said.The Ministry of Railways said on its website that it has asked its local branches to be prepared for the upcoming icy weather.Meanwhile, the local authorities in big cities have been bracing for the arrival of massive numbers of travelers as the Spring Festival holiday winds down.In Shanghai, tens of thousands of public transportation workers cut their holidays short and put 27 additional bus lines on the road to meet demand as passengers began arriving in large numbers at the city's railway stations.The influx began on Saturday night, according to local newspaper Wenhui Daily.On Sunday, the pressure intensified on the Qinghai-Tibet railway, two days earlier than expected.As a result, the railway company organized additional workers to facilitate the flow of people through Xining Railway Station in Northwest China's Qinghai province.Many volunteers have also been pitching in to help keep people moving and have offered to do various jobs at stations, such as helping people buy tickets and assisting them in checking their travel schedules.Among them, Liu Chen, a student from the Guangzhou-based Zhongkai University of Agriculture and Engineering, has been helping people at Guangzhou Railway Station by carrying their bags."One day, I helped more than 70 passengers with their luggage and, after all of them got on the trains, it felt like my legs were almost paralyzed," he said.The Hohhot railway bureau in North China's Inner Mongolia autonomous region said it is expecting so many extra passengers that it has scheduled four additional trains for lines to Chongqing and Beijing.With so many people scrambling to get back from family gatherings and holidays to their jobs in China's big cities, the rush to buy tickets has been phenomenal. Tickets for trains that will leave Nanjing on Tuesday for Beijing, Guangzhou, Harbin and Changchun had virtually all gone on Monday morning, Jiangsu's Yangtse Evening Post reported.On Sunday, the fourth day of Spring Festival, the country's railways carried a total of 5.3 million travelers, which was up by 12.8 percent on the 4.7 million who rode the rails a day earlier, according to the Ministry of Railways.Another 38.6 million travelers made Spring Festival trips on Sunday on buses and ships, according to the Ministry of Transport.The traditional chunyun period, or Spring Festival travel season, runs for 40 days and is calculated in two phases: 15 days before Spring Festival Eve and 25 days after it, as stipulated by the central government.China's railways moved about 77.3 million passengers during the first 15-day period, which ran from Jan 19 to Feb 2, the Ministry of Railways reported.
来源:资阳报