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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.

BEIJING, Feb. 19 (Xinhua) -- As the traditional Spring Festival season ended two days ago, a new wave of post-holiday travel rush came to China's railway system, the Ministry of Railways (MOR) said Saturday.According to a statement from the MOR, the nation's railways carried 6.49 million passengers on Friday, the first day after the Lantern Festival which ended the festival season.The new wave of passengers mainly included students going back to school for the new semester and migrant workers returning to cities to start work. On Friday alone, 919,000 student passenger trips were made on railways, said the MOR.The ministry expected the travel volume and duration of the new peak to be similar to the previous year, with an average of more than 6 million railway passenger trips a daily.The MOR figures also showed that 166 million trips were made on railways since the Spring Festival travel rush began on Jan. 19, up 6 percent from the same period last year.

BEIJING, March 6 (Xinhua) -- China aims to "basically eradicate poverty" by 2020 while greatly raise its poverty line, in order to help more people in need, Chinese Premier Wen Jiabao said here Sunday.The State Council is drafting a new ten-year poverty-reduction plan (2011-2020), in which the current poverty line of 1,196 yuan per year (about 0.5 U.S. dollars a day) will be greatly raised, Wen told a panel meeting of the ongoing session of the National People's Congress (NPC).The nation will intensify its poverty alleviation efforts through aids and development, focusing on large areas of destitute population, he said to a group of NPC deputies from Gansu, one of the poorest regions in China.According to the United Nations' standard of one dollar per person each day, China still has 150 million people under the poverty line.Wen said lack of water was the bottleneck for Gansu's social-economic development, urging the province to expand the use of water conservancy technology.Wen also urged the province to coordinate economic development with environmental protection, and reverse environmental degradation in Dunhuang, a historical city with world cultural heritage threatened by decertification.

CHICAGO, Jan. 20 (Xinhua) -- Chinese President Hu Jintao arrived here on Thursday afternoon from Washington, after meetings with U.S. President Barack Obama on major bilateral and world issues.During their talks Wednesday, the two leaders agreed to build a China-U.S. cooperative partnership based on mutual respect and mutual benefit.In Chicago, Hu will meet local officials and visit a high school, Chinese officials said.Chinese President Hu Jintao (R front) meets with Mayor of Chicago Richard Daley(L front) in Chicago, the United States, Jan. 20, 2011. Hu arrived in Washington Tuesday for a four-day visit to the United States. The trip, his second as head of state, is aimed at enhancing the positive, cooperative and comprehensive relationship between China and the United States.The Chinese president visited the United States in April 2006.

LOS ANGELES, April 2 (Xinhua) -- The United States could soon be faced with an epidemic of Non-Alcoholic Fatty Liver Disease ( NAFLD), one of the major contributing factors of chronic liver disease (CLD), the American Association for the Advancement of Science (AAAS) reported Saturday.If the current rates of obesity and diabetes continue for another two decades, the prevalence of NAFLD in the U.S. is expected to increase by 50 percent in 2030, AAAS said.The prediction is based on pre-existing clinical survey data over a 10 year period (1988-1994, 1999-2004 and 2005-2008), which included 39,500 adults from three survey cycles, according to the AAAS.Over the three cycles, the prevalence of NAFLD doubled from 5. 51 percent to 11 percent respectively. Furthermore, during the first survey cycle (1988-1994) 46.8 percent of all CLD's was related to NAFLD but by 2005-2008 this had increased to 75.1 percent. In addition, the prevalence of obesity and diabetes, the two key risk factors for NAFLD also steadily increased."If the obesity epidemic is anything to go by, the U.S. NAFLD epidemic may have a ripple effect worldwide," said Mark Thursz, Vice Secretary of the European Association for the Study of the Liver. "It is imperative that health systems continue to drive effective educational programs to reinforce awareness among the general public to alert them of the risks of obesity and promote the importance of diet and exercise."Non-alcoholic fatty liver disease is fast becoming one of the top concerns for clinicians due to the obesity epidemic and it's potential to progress to advanced liver disease which significantly impacts on overall liver-related mortality, Thursz said in remarks published by AAAS' website EurekAlert.org.NAFLD, considered as one of the major causes of morbidity and mortality worldwide, is the term used to describe fat build-up in liver cells in people who do not drink alcohol excessively. The disease is the most common persistent liver disorder in Western countries with an estimated overall prevalence of 20-30 percent, according to AAAS.NAFLD encompasses a spectrum of liver disease associated with insulin resistance, diabetes and obesity and as such people most at risk of NAFLD are those who are obese, have insulin resistance associated with diabetes, high blood pressure and cholesterol.