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SAN DIEGO (KGTV) — Twin brothers were arrested in Mexico this week and turned over to U.S. border authorities in connection with a 2013 murder in East San Diego.Anibal and Edward Avila, both 27, were arrested on Friday and charged with the murder of Rafal Robles, 34, five years ago, according to San Diego Police.Police say Robles and another man were found suffering from gunshot wounds in an alley near the 4000 block of 39th Street in the Cooridor neighborhood just before 3 p.m. on April 11, 2013. Both men were taken to a nearby hospital, where Robles died shortly after arriving.MAP: Track crime happening in your neighborhoodDetectives identified the Avila brothers as the suspects behind the fatal shooting, though they remained at large and were believed to have fled to Mexico.Police did not offer a motive for the shooting.The twins are due in court Nov. 6. 882

SAN DIEGO (KGTV) -- While San Diego County remains in the red tier of California’s tiered reopening plan, many local gyms and fitness centers continue to struggle to operate at 10 percent capacity.For some, it’s just not enough to survive, and business owners have to make difficult decisions.“Our rent doesn’t change whether we have one person in class versus 25,” said Taylor Hollenkamp, owner of BarreBody Studios in Pacific Beach and Tierrasanta.Days ago, Hollenkamp sent a notice out to members of BarreBody Studios, announcing the fitness studio would be closing after nearly a decade in business.“With no end in sight of things going back to normal, I had to make the decision to close permanently because the business is just hemorrhaging money,” she said.Others in the San Diego fitness industry can relate to the pain Hollenkamp is experiencing.“You can’t run a business, you can’t advertise, you can’t bring in new clients,” said Matt Ceglie, a personal trainer, and co-creator of the Strongist app, which allows users to track and log workouts.He said he has not been able to train any of his clients in a private Carmel Valley gym since March.“I had about 25 clients that I worked with on a weekly basis, now I train about nine of those clients in their homes or remotely,” said Ceglie. “It’s almost impossible right now in the tier we’re in to run your gym at 10 percent capacity.”When it comes to California’s reopening tiers, San Diego is currently in the red tier, allowing gyms and fitness centers to operate at 10 percent capacity.If San Diego County’s COVID-19 numbers improve and we move to the orange tier, they could open inside at 25 percent capacity. In the yellow tier, which is considered the best, it’s 50 percent capacity.With no exact solutions to the loss of income or path to a full reopening, more small business owners have to say goodbye to the dreams they worked hard to make a reality.“I’ve been building this business for 25 years, and it goes away just like that,” said Ceglie.“I was so passionate about the fitness industry, and this has just caused such a heartache for me and so much stress that it’s not fun for me anymore,” said Hollenkamp. “This has been my career, and I don’t know what I’m going to do after this.” 2269

SAN DIEGO (KGTV)-- A San Diego-based genetics company received the FDA's Emergency Use Authorization for its revolutionary type of COVID-19 testing. The new test not only provides a positive or negative reading, but it also provides vital genetic information that can help create a vaccine.From concept to the FDA's emergency use authorization, the San Diego-based team at Illumina worked at warp speed."The idea came 58 days ago," Susan Tousi, Sr. VP. of Production and Development at Illumina said. "It took a village of all of us in San Diego to make that happen."There are already many different types of COVID-19 tests on the market.But the scientists and engineers at Illumina came up with a test that reveals a lot more."Our test not only gives you a yes or no answer for the presence of the virus, but it also gives you the genetic sequence of the virus," Tousi said.On Tuesday, the FDA approved the Emergency use of the world's first COVID-19 test that also shows the biological makeup of the virus.The results can help researchers track and trace the virus and study different mutations over time and in different regions."Knowing this is really critical, not only to the development of effective vaccines but also for us to detect its presence, recurrence, and whether there is a mutated form that we need to be prepared for," Tousi said.The sample is collected via nose or throat swab and sent to the lab.A sequencing machine can run up 43,000 samples a week. From swab to results, it takes only 24 hours."This was the culmination of an incredible amount of work. And I'm confident we're going to make a big difference in the fight against COVID," Tousi said. "The understanding of this virus at the genetic level is going to make all of the difference in the world in fighting this and future disease."The company has already started to ship its tests to large labs across the world. 1904

SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562

SAN DIEGO (KGTV) — Two San Diego Naval Special Warfare sailors have tested positive for coronavirus.The sailors, who tested positive Sunday, are the first two NSW personnel confirmed with the virus in Navy Region Southwest. They are isolated at their homes, according to Naval Special Warfare Command Public Affairs.Those who were in close contact with the two sailors are being quarantined in accordance with Centers for Disease Control and Prevention guidelines.RELATED: Navy closes San Diego Training Support Command after third coronavirus caseThere are now six NSW sailors with coronavirus, according to the Navy. Four sailors are currently isolated at Naval Base Kitsap-Bangor in Washington state."U.S. Special Operations Command and the Navy are committed to taking every measure possible to protect the health of our force. We remain in close coordination with local agencies, base tenant commands, and public health authorities to ensure the well-being of our personnel and the local community," the Navy said in a release. 1040