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The U.S. experienced its largest single-day increase in new COVID-19 cases on Thursday according to figures from Johns Hopkins University.Johns Hopkins public database reports that about 40,000 confirmed cases of the coronavirus were reported to local health departments on Thursday. The previous one-day record for newly reported cases occurred on April 24, when about 36,000 were confirmed to have contracted the virus.According to Johns Hopkins, 2.4 million Americans have contracted the virus, and more than 124,000 have died after contracting it.A graph showing the number of new cases of COVID-19 reported each day in the U.S. (Johns Hopkins)New cases of the coronavirus are currently on the rise in several regions throughout the country. While top federal officials, including President Donald Trump, have maintained that the increase in cases can be attributed to an increase in testing, other concerning statistics, like hospitalizations linked to the virus, are also on the rise.On Thursday, Texas paused efforts to lift lockdown restrictions put in place earlier this year to prevent the spread of the virus. Other local governments have enacted mandates requiring masks in public.Vice President Mike Pence will hold a press conference along with the White House coronavirus task force on Friday in response to the rising case numbers. 1355

The US Secret Service is investigating the vandalism of a sign at the Trump International Golf Club in West Palm Beach, Florida.The West Palm Beach Sheriff's Office told the White House press pool that the Secret Service is looking into red paint that was splattered on the sign outside of the entrance of the club. Crews were spotted cleaning the sign early Sunday morning.A spokesman for the Secret Service said they are "aware of the incident."West Palm Beach is a frequent getaway for President Donald Trump and his family. He was spotted at the golf club this weekend while in town residing at his nearby property, Mar-a-Lago over the Easter holiday. 693

The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The sky is lovely, dark and deep. But these golfers in Hawaii have rounds to go before they sleep.Stunning photos taken at Hawaii's Big Island on Tuesday show golfers coolly hitting the links even as a monstrous ash plume looms behind them.The eruption of the Kilauea volcano has already destroyed houses, caused evacuations and threatened to wreak havoc on Hawaii's tourism industry. On Tuesday, a plume of ash from the volcano rose 12,000 feet into the air, dropping ash on sections of the island.The US Geological Survey issued a red alert on Tuesday warning of an imminent major eruption.But clearly, not everyone was so worried. 646

The South Georgia Islands might not be permanently populated by humans, but it is an important sanctuary for penguins, seals and other various creatures in the South Atlantic.But a giant iceberg, A68a, could threaten the wildlife on the islands, according to the Government of South Georgia & the South Sandwich Islands.With the assistance of the Royal Air Force, the government has been tracking the iceberg’s movement toward the islands. While the islands do not have a permanent population, they are visited by tourists and others.According to the BBC, A68a was 150 kilometers from South Georgia. The concern is the iceberg could disrupt breeding for penguins on the island.“We are now entering the key part of the year for breeding," Mark Belchier, director of fisheries and environment for the government of South Georgia & the South Sandwich Islands, told BBC News."The nests have been built for gentoo penguins, and eggs will be laid soon. And the first seal pups have been born in the last fortnight," he added.The islands used to be populated on a more permanent basis as a small settlement ran a whaling station.Before air travel, the islands were used by explorers to prepare for treks to Antarctica. Whalers on the island also played a key role rescuing Sir Earnest Shackleton’s crew after his expedition became stranded on Antarctica’s Elephant Island. 1381

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