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SAN DIEGO (KGTV) – The American Red Cross of San Diego/Imperial Counties opened a shelter Thursday night for residents displaced by flooding from heavy rainstorms.The shelter opened around 9:30 p.m. at the Paradise Valley Seventh-day Adventist Church on East 8th Street in National City.Services include a safe and clean place to stay, food, hydration, comfort kits with personal hygiene items, emotional support and health services, according to the Red Cross. The shelter will stay open as long as there is a need.In response to the flooding caused by today’s rainstorms, #RedCross disaster workers are working to open a shelter this evening at the Paradise Valley Seventh Day Adventist Church (2701 East 8th Street, National City, CA 91950). The shelter is anticipated to be open by 9:30 p.m.— SDIC Red Cross (@SDICRedCross) December 7, 2018 852
SAN DIEGO (KGTV) — The alarm blares in your ears, as your eye lids slowly peak open and usher in a flood of sunlight. You drag your feet along the floor to the kitchen, where a device that has saved mornings for so many awaits you.Coffee is often regarded as a necessity to begin the day, but sometimes it's just what the doctor ordered for a relaxing day. In San Diego, several local coffee roasters and houses blend together their unique coffee recipes that can both kickstart your day or provide a warm moment of solace.And as National Coffee Day comes on Sept. 29 this year — a Sunday — there's no better time to wake and relax at a coffee house before the work week kicks into gear. While you're out and about, be sure to duck into one of San Diego's many coffee houses to sample their invigorating drinks:Bird Rock Coffee Roasters (Locations in La Jolla, Bressi Ranch, Little Italy, Torrey Pines, Morena, Pacific Beach): Bird Rock boasts high-quality coffee, their own signature mixes, and seasonal blends of delicious coffees at their locations around town.Better Buzz (Locations in La Jolla, Pacific Beach, Hillcrest, Encinitas, Fashion Valley, Point Loma, Mission Beach, San Marcos): In addition to their signature drinks like "Best Drink Ever" and "Hazelnut Divinity," Better Buzz offers delicious cold brews, mochas and lattes, and eats to match.Dark Horse Coffee Roasters (Locations in Normal Heights, North Park, Golden Hill, La Mesa): Head over to Dark Horse Coffee Roasters for their signature Espresso drinks, like “The Champ” or cold brew on nitro with a splash of vanilla bean syrup.Lofty Coffee & Bakery (Locations in Solana Beach, Encinitas, Little Italy): Lofty Coffee roasts its own beans and crafts pastries from scratch at hubs along San Diego's coastal communities.Jennings House Cafe: One of San Diego's oldest coffee brands, Jennings House Cafe serves up Cura Coffee and delicious breakfast dishes in a historic landmark home dating back to 1886.The WestBean Coffee Roasters (Locations in downtown, Liberty Station, Bankers Hill): WestBean sources its own beans, churning out some delicious espressos and refreshing cold brews.James Coffee Co. (Locations in Little Italy, Bankers Hill, downtown, Columbia): James Coffee Co. puts together your traditional brews plus some delicious specialty drinks with honey cinnamon, Mexican mocha, or coffee soda.Philz Coffee (Locations in La Jolla, Del Mar, Encinitas): The Bay Area brings specialty beans — 28 types of beans, in fact — involving a variety of flavors like grapefruit, Cherry, maple, and others.Refill: Refill packs its java house with all the needed brews: Mochas, lattes, cappuccinos, and some delicious cold brew concoctions and crepes.Modern Times: In Modern Times' Lomaland Fermentorium, the brewery roasts its own beans in a modest roaster beside taps of its brews. And of course, so of those beans have crossed over to combine barrel-aged beans.Heartwork: San Diegans have long been fans of Heartwork's brews using James Coffee Co. and Dark Horse roasted beans.Moniker Coffee Co.: A variety of small-batch coffee from local producers and some out-of-town roasters can be found at Moniker's Liberty Station stop.Communal Coffee (Locations in South Park, North Park): Grab a cup of coffee and flowers on the side! Communal Coffee, which serves Sightglass Coffee from San Francisco. Expect some creative drinks like rose vanilla, taro, and sea salt and caramel coffees.Revolution Roasters (Location in Oceanside): Fresh-baked pasteries, breakfast dishes, and of course, an awakening variety of coffees awaits at Revolution Roasters, including their signature Lavender Honey and Butterscotch lattes.SkyBound Coffee + Dessert Lounge (Locations in Vista, Downtown San Diego): Whether you want your coffee hot or cold, SkyBound has what you need with their Skybound Dark Chocolate Mocha, iced lavender vanilla, sea salt, or VanillaCali coffees.Perks Coffee House (Location in San Marcos): Delicious cold brew on tap, freshly roasted beans, and a variety of Espresso drinks will surely perk your senses at Perks Coffee House. Keep an eye on their seasonal Cafe Viennese, Dirty Chai latte or go for something a little harder like Irish Coffee. 4234

SAN DIEGO (KGTV) - The family of a teenage woman shot and injured at Sunset Cliffs updated her condition Friday.The unidentified 19-year-old victim was shot twice and left to die on the stairs near the ocean, a GoFundMe account set up by her aunt reported.A person walking near Ladera Street and Sunset Cliffs Blvd. found the woman bleeding the morning of April 12 and called police. The victim had no idea what happened to her, police said.RELATED: Woman with gunshot wounds found at Sunset CliffsShe suffered a ruptured ear canal, spinal surgery, loss of feeling in her fingers and legs, and damage to her spinal cord, according to the GoFundMe page.Her family is anticipating months of physical therapy and is asking for money for medical and household bills while her mother is by her side. 802
SAN DIEGO (KGTV) — The COVID-19 pandemic has been tough on kids, as they have been stuck at home for school and for play. However, a second-grader from the College Area is putting his time to good use. Seven-year-old Max Kelley came up with an idea to help feed those in need. Max and his younger sister Lucy were playing out in the backyard when he approached his mom with an idea of wanting to start a business."He wanted to do a water recycling business," says his mom Lauren. "So we went around collecting water bottles and cans. We went around to high schools, the bay, and the beach. Every week, we would return it to the recycling center, and we would get the money."And while some kids might take the money to buy something for themselves, Max wanted to do something completely different, and completely unselfish. His first thought was to think of others, and how the money might benefit somebody else."I realized that there are people in need," says Max. "And need food and water." His mother wasn't surprised at all, describing her son as very caring."He came up with the idea himself, and that was to donate the money to a local food bank," Lauren said.So the day before Thanksgiving, Max, Lucy, and the family donated their collection of 8.43 to the Special Delivery Food Bank in Mission Hills. "My family and the kids all got a standing ovation from all the patrons that were there," says Lauren.One check has been delivered, but Max is definitely not finished giving to those in need. As he and Lucy have plans to raise even more money for the food bank. "It made me feel happy," Max said. 1616
SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223
来源:资阳报