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The Department of Labor reported Thursday that 1.8 million Americans filed initial claims for unemployment during the week ending May 30, bringing an 11-week total to about 42 million. 196

The government shutdown is approaching the two-week mark with no end in sight. And now that the holidays are over, its effects are becoming more apparent -- not just on federal workers' salaries, but on everything from science to beer.Here are some surprising impacts of the government shutdown:Low-income moms and their kids may not get nutritional assistance 373

The Houston Astros fired assistant general manager Brandon Taubman on Thursday for directing inappropriate comments at female reporters during a clubhouse celebration, announcing the decision in the middle of the World Series and putting a renewed spotlight on domestic violence in baseball.Astros general manager Jeff Luhnow apologized for the team’s initial response Monday, which was to accuse a Sports Illustrated reporter of making up the story.“That original reaction by the Astros was wrong, and we own it as an organization,” Luhnow said during a news conference at Nationals Park, a day before Game 3.“There were many people involved in reviewing that and approving that. And I’m not going to get into the details of that. ... But regardless of who wrote it and who approved it, it was wrong. It was incorrect. It should never have been sent out. We’ve learned a lesson about it,” he said.Taubman had apologized Tuesday for using language that was “unprofessional and inappropriate” in the Astros clubhouse following Saturday night’s pennant-clinching victory over the New York Yankees.SI reported Taubman repeatedly yelled toward a group of female reporters about closer Roberto Osuna, who was suspended for 75 games last year for violating MLB’s domestic violence policy and then was traded from Toronto to the Astros.Taubman shouted “Thank God we got Osuna!” according to SI, which said he made similar remarks several times, punctuating them with a profanity. Taubman’s behavior was corroborated by reporters for The Houston Chronicle and Yahoo.After an investigation by Major League Baseball and the Astros, Luhnow met with Taubman on Thursday and fired him before the team traveled to Washington in what Luhnow termed “a pretty tough conversation.”Taubman did not respond to a text from The Associated Press seeking comment.Houston’s initial statement Monday claimed SI tried to “fabricate a story where one does not exist” and maintained Taubman’s comments weren’t directed at reporters. Luhnow said he was among the Astros officials who saw the statement before it was issued.“There’s nothing about that first statement that was correct or that’s defensible,” Luhnow said. “The original impression that we had, without doing an investigation — and that’s our fault for not doing the investigation — was that it was two colleagues talking who were overheard and the comments were not directed at anybody in particular, not meant to be mean-spirited in any way or offensive in any way, just supportive of the player who had had a bad night.”“But as we continued to investigate, it was clear that they were intended to be heard. And they were completely inappropriate,” he said.Luhnow said the Astros decided Wednesday “that we were going to take action unilaterally ahead of Major League Baseball making any recommendations.” He said Taubman’s behavior did not indicate a wider problem in the Astros’ front office.“This is not something that’s endemic. This is not a cultural issue,” he said. “We have a lot of really good people in our front office, in our coaching staff, and our team.”Houston apologized to the SI reporter, the magazine and people who saw the incident, and to those who were offended.“The Astros are very committed to using our voice to create awareness and support on the issue of domestic violence,” the team said in a statement.Astros manager AJ Hinch has been critical of Taubman’s behavior since the SI report came out.“I continue to be disappointed and just sorry it happened,” Hinch said.A 2007 graduate of Cornell with a degree in applied economics, Taubman worked for Ernst & Young and then as an analyst in the equity derivatives group of Barclays Investment Bank before he was hired by the Astros as an analyst in June 2013.He was promoted to manager of baseball operations before the 2014 season, director of baseball operations in October 2015, senior director of baseball operations in August 2017 and assistant general manager in September 2018, tasked with major league administrative functions and oversight of analytics and pro player scouting. The Astros announced a contract extension on Sept. 30 and a wider role as assistant general manager, player evaluation.“He’s been a valuable employee. We hired him over five years ago, he’s moved up quickly in the organization,” Luhnow said. “He’s smart. He’s hard working. And these comments that he made were out of character. He hasn’t had this type of incident before. This is not a repeating pattern of anything, which is why it was so easy for us to believe that it was more innocent than it turned out to be.” 4630

The 2019 Nobel Prize for Medicine has been jointly awarded to William Kaelin Jr., Sir Peter Ratcliffe and Gregg Semenza for their pioneering research into how human cells respond to changing oxygen levels.Announcing the prize at the Karolinska Institute in Stockholm on Monday, the Nobel committee said that the trio's discoveries have paved the way for "promising new strategies to fight anaemia, cancer and many other diseases."The 2019 medicine laureates, the committee added, have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.The importance of oxygen has long been established, the committee explained, but how cells adapt to changes in its levels remained unknown.Randall Johnson, prize committee member, described the trio's work as a "textbook discovery.""This is something basic biology students will be learning about when they study, at aged 12 or 13, or younger, biology and learn the fundamental ways cells work. This is a basic aspect of how a cell works and, from that standpoint alone, it's a very exciting thing."The winnersNew York-born Kaelin established his own research laboratory at the Dana-Farber Cancer Institute in Boston and became a full professor at Harvard Medical School in 2002.Semenza, also born in New York, became a full-time professor at Johns Hopkins University in 1999 and since 2003 has been the Director of the Vascular Research Program at the Johns Hopkins Institute for Cell Engineering.Ratcliffe, who was born in Lancashire, England, studied medicine at Cambridge University and established an independent research group at Oxford University, becoming a full professor in 1996. 1694

The husband of a woman killed in the Poway synagogue shootings spoke Monday to a crowd at the Mesa Arts Center near Phoenix. The event was planned before the recent 177