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WASHINGTON, Dec. 21 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Wednesday approved Isentress for the treatment of HIV-1 infection for children and adolescents.The drug is part of a class of medications called HIV integrase strand transfer inhibitors that works by slowing the spread of HIV in the body. It was first approved for use in adult patients in October 2007, under FDA's accelerated approval program."Many young children and adolescents are living with HIV and this approval provides an important additional option for their treatment," said Edward Cox, director of the Office of Antimicrobial Products in the FDA's Center for Drug Evaluation and Research.Isentress is a pill that can be taken twice daily, with or without food. The pill is also available in a chewable form. As the two tablet formulations are not interchangeable, the chewable form is only approved for use in children ages 2 to 11.A single, multi-center clinical trial of 96 children and adolescents aged 2-18 years with HIV-1 infection evaluated the safety and effectiveness of Isentress. These patients previously received treatment for HIV-1 infection. After 24 weeks of treatment with Isentress, 53 percent of these patients had an undetectable amount of HIV in their blood.According to the FDA, the most commonly reported severe, treatment-related side effects in patients taking Isentress include trouble sleeping and headache. The frequency of these side effects is similar for children and adults. One pediatric patient reported severe treatment-related insomnia, while another pediatric patient experienced a drug-related skin rash.
HONG KONG, Oct. 13 (Xinhua) -- Computer and electronic device maker Lenovo, listed in both Hong Kong and New York, has replaced Dell to become the world's second largest personal computer company, Lenovo said Thursday.Lenovo made the remarks in a statement, citing figures released by International Data Corporation (IDC), a global provider of business intelligence for the consumer technology market.Following five quarters as the fastest-growing PC maker among the world's top vendors, the preliminary IDC data reported that Lenovo has achieved record market share of around 13.7 percent and record quarterly shipment volume of some 12.6 million units.Lenovo CEO Yang Yuanqing said his company had surpassed two competitors to capture the No. 2 spot in worldwide PCs in just two quarters and it was the highest rank that Lenovo has achieved in worldwide PC sales.Given current competitive environment, the new achievement positioned Lenovo as a strong challenger to ultimately become the global market leader, Yang said in the statement."We are growing in the enterprise and the consumer space. And our customers know we are fully committed to the PC market for the long term," he said.At the same time, the Chinese multinational would continue investing in innovative products that would help drive the convergence of technologies and services across all four screens -- smart phones, tablets, PCs and smart TV, Yang said."We must deliver a great user experience across all platforms to achieve our goal and become the leading personal technology company in the world."Lenovo is a personal technology company and a global Fortune 500 company with annual sales worth 21 billion U.S. dollars. It serves customers in more than 160 countries and regions.
HELSINKI, Nov. 7 (Xinhua) -- A data leak was uncovered in Finland Saturday, in which personal details of around 16,000 people were uploaded onto a file-sharing website, according to Finnish media report on Monday.This act of sabotage is the largest ever of its kind in Finland. The data leak is being looked into by the Finnish National Bureau of Investigation.Anonymous Finland claimed on Monday responsibility for the publication of personal details of thousands of Finns. The group temporarily published a sample of information on 16,000 people as proof of the hack. The hack was motivated by an apparent desire to shame the Finnish government into improving data security.Finnish National Bureau of Investigation has not confirmed the claims that a loose group of hackers known as Anonymous was behind the data leak.The list that was put on the Internet contains the names, full social security numbers, addresses, telephone numbers, street addresses, and email addresses of the victims. Several upper secondary vocational education institutions are on the list, and some civil servants and students of the Police College of Finland are mentioned by name.Finnish police have confirmed that the names of some Finnish Defense Forces staff are on the list. Finnish Defense Forces found out that fewer than 10 of its employees are included, and has informed these people. The military said the leak did not pose a security threat.
BERLIN, Jan. 17 (Xinhua) -- Researchers in Germany have found a cheap and easy way to synthesize anti-malaria drug in large quantities from waste materials, said the Max Planck Society on Tuesday.Currently there are nearly one million people die worldwide each year due to lack of effective drugs, as sweet wormwood, from which artemisinin, the effective essence to fight malaria can be extracted, only grows in China, Vietnam and a few other countries.However, researchers in Germany have now developed a simple process for the synthesis of artemisinin in laboratory, using artemisinic acid, a substance contained in the by-product, or waste materials of the isolation of artemisinin from sweet wormwoods, as row materials of synthesizing artemisinin."The production of the drug is therefore no longer dependent on obtaining the active ingredient from plants," said Peter Seeberger, director at the Max Planck Institute of Colloids and Interfaces in Potsdam and professor at Free University of Berlin.The artemisinic acid in the waste material boasts a volume 10 times greater than the active ingredient itself, said Seeberger, and they could be turned into artemisinin in four and a half minutes in a so-called continuous-flow reactor.Seeberger estimated that 800 of the reactors would be enough to cover the global requirement for artemisinin, and the whole innovative synthesis process could be ready for technical use in three to six months.Malaria is a disease caused by parasites that are transmitted to people through the bites of infected mosquitoes. In 2010, malaria caused an estimated 655,000 deaths, mostly among African children.
SAN FRANCISCO, Jan. 26 (Xinhua) -- Global tablet shipments reached nearly 27 million units in the fourth quarter of 2011 with Android jumping to a record share of 39 percent, said a new research released on Thursday.According to the research by consulting firm Strategy Analytics, global tablet shipments reached a record high of 26.8 million units in the last quarter of 2011, surging 250 percent from 10.7 million units in the same period a year earlier.Android captured a record 39 percent share of global tablet shipments, rising from 29 percent in the year-ago quarter.Global Android tablet shipments tripled annually to 10.5 million units in the last three months of 2011 and the platform so far is relatively popular with tablet manufacturers, said the research.However, Apple shipped 15.4 million iPads worldwide and maintained its market leadership with 58 percent share during the fourth quarter last year."Apple shrugged off the much-hyped threat from entry-level Android models this quarter," Peter King, director at Strategy Analytics, said in a statement.The research found Microsoft captured a mere 1.5 percent global tablet share in the quarter, noting that "the upcoming release of Windows 8 this year cannot come quickly enough for Microsoft, so its hardware partners can start competing more effectively in the tablet space."In the full year of 2011, global tablet shipments hit 66.9 million units, increasing by 260 percent from 18.6 million units in 2010, according to the research.Consumers are increasingly buying tablets in preference to netbooks and even entry-level notebooks or desktops, said the research.