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The Republican National Committee has withdrawn from a joint fundraising agreement with Roy Moore, according to a Federal Election Commission filing posted Tuesday, as the GOP establishment continues to break ties with the Alabama Senate candidate.The National Republican Senatorial Committee was the first to drop itself from the agreement, which benefits Moore's campaign, ending its participation last Friday, according to FEC filings. 466

The U.S. continues to lead the world in deaths linked to COVID-19 with more than 222,000 — and some experts believe that figure is much higher. But according to a new study, at least 130,000 of those deaths could have been avoided.According to a study by the National Center for Disaster Preparedness at Columbia University, the U.S. could have avoided between 130,000 and 210,000 COVID-19 deaths had the country adopted mitigation policies similar to those used by other "high-income nations."It's clear that the U.S. has disproportionately felt the affects of the pandemic — though it has just 4% of the world's population, it accounts for 20% of COVID-19 cases worldwide. The U.S. death toll stands in stark contrast to countries with similar resources, like South Korea, Japan, Australia, Germany, Canada, and France.To calculate the U.S.'s "avoidable deaths," the study applied the death rates of those countries to the U.S.'s population. Researchers then subtracted that figure from the U.S.'s current death count.By that calculation, researchers concluded that 130,000 lives could have been saved had the U.S. adopted policies similar to that of Canada's, and that as many as 215,000 lives could have been saved had the country adopted policies similar to South Korea.In explaining why U.S. deaths are disproportionately high, the Columbia researchers cited four key mistakes:Insufficient testing capacity: Researchers cited issues the U.S. had early on in the pandemic in developing and acquiring tests, while countries like South Korea were prepared almost immediately to test for the virus on a widespread scale.Delayed response: A previous Columbia University study determined that instituting national social distancing measures just one or two weeks earlier would have saved 36,000 of lives.Lack of a national mask mandate: Top health officials recommended against masks early on in the pandemic, fearing that doing so would lead to a shortage. Even today, masks have become politicized in some circles despite evidence showing that wearing one reduces the spread of droplets that can carry the virus.Failure from federal leadership: The Columbia study cited the Trump administration's "hostility to much of the critical guidance and recommendations put forth by its own health agencies," specifically citing the president's attempts to "downplay" the virus.Read more about the Columbia University study here. 2430

The US Food and Drug Administration on Thursday announced the approval of?the first generic version of EpiPen.The auto-injector pen delivers the drug epinephrine to patients experiencing a severe allergic reaction that, if untreated, could develop into the life-threatening condition of anaphylaxis. The medication is delivered into a muscle as a single dose, like a shot, through an injector pen with a spring.Allergies from food, bug bites, medications and latex can cause life-threatening reactions.The newly approved generic is made by Teva Pharmaceuticals and offers an alternative for patients who, until now, have been able to use only the brand-name EpiPen made by Mylan. It is approved in a smaller dose for children, as well.There are two other brand products on the market for a severe allergic reaction: Adrenaclick and Auvi-Q.The newly approved option made by Teva is the only approved non-brand option and can be substituted only for Mylan's EpiPen."Today's approval of the first generic version of the most-widely prescribed epinephrine auto-injector in the U.S. is part of our longstanding commitment to advance access to lower cost, safe and effective generic alternatives once patents and other exclusivities no longer prevent approval," FDA Commissioner Dr. Scott Gottlieb said in a statement announcing the approval.In recent years, Mylan came under fire for a price increase that put the product out of reach for many who needed to keep the drug on hand. 1488

The Tuesday after Thanksgiving may be known as Travel Deal Tuesday, a day offering deals on airfare. But Cyber Monday is the day to book your dream vacation.  If you’re looking to take a family vacation, you may want to look at Universal Studios and Universal Island Treasure in Orlando.On undercovertourist.com, you can get two-day park tickets, plus two extra days free, if you buy today. That’s a total of 3 for four people for four full days. If you want another option for warm weather, you could travel to Miami and take an all-inclusive three-day Royal Caribbean cruise to the Bahamas. If you buy one full-price ticket, you’ll get your second one 60 percent off. The third and fourth ticket will be 30 percent off!The total cost for a family of four will cost 5. The deal can be found on americandiscountcruises.com.Have you always wanted to go to the Grand Canyon? If you take the Grand Canyon train tour, you can save 50 percent on your once in a lifetime trip.Thetrain.com is offering a three-day, two-night stay in Williams, Arizona for 5 for two people. That's a 0 savings.If the west coast is more your style, a family of four can head to LEGO Land for a crazy good deal. LEGO is offering 30 percent off rooms and 50 off two-day LEGO Land tickets on their website. You can get all of that for 1 per person for a two-day stay. 1381

The United States has more than double the rate of premature overdose deaths of at least 12 other countries, according to a new?study.The research, published Monday in the Annals of Internal Medicine, says that there were an estimated 63,632 drug overdose deaths in 2016 in the US."The U.S. has the highest death rate due to drug overdoses for both men and women (35 deaths in 100,000 men and 20 deaths in 100,000 women) in 2015, more than double those of any other country in our study," Yingxi Chen, one of the researchers and a postdoctoral fellow at the National Institutes of Health's National Cancer Institute, wrote in an email.Mexico had the lowest rates: 1 death per 100,000 men and 0.2 deaths per 100,000 women.The researchers also found that the United States had the second-highest increase in drug overdose deaths: 4.3% per year in men and 5.3% per year in women, Chen said. Only Estonia had a higher increase.Norway was found to have the biggest decrease in drug overdose mortality for the whole population. Decreases were also found among men and women in Mexico, Spanish men and Danish women.Researchers "looked at the trends and patterns of drug overdose deaths among people age 20 to 64 years in 13 countries of the Organisation for Economic Co-Operation and Development?between 2001-2015," Chen said.These countries were Australia, Chile, Denmark, England, Wales (the data for these two countries was combined), Estonia, Finland, Germany, Mexico, the Netherlands, Norway, Spain and the United States."I think it reinforces what we know about the United States but also points out some of the contrast in terms of the ways other countries have dealt with similar issues," said Caleb Banta-Green, principal research scientist at the University of Washington Alcohol and Drug Abuse Institute, who was not involved in the research.Banta-Green and the researchers both point out that opioids play a part in the high levels of drug overdose deaths in the US.The study describes US opioid deaths as "triple epidemic waves," starting with prescription opioid deaths in the late 1990s, heroin deaths beginning in 2010 and finally deaths due to synthetic opioids, which include fentanyl.Other countries have found solutions to high rates of opioid-related deaths, according to Banta-Green, who cited France, which was not included in the research."When France got rid of the restrictions on prescribers using the medication buprenorphine, their national mortality, opiate overdose mortality rate dropped 79%," he said.Buprenorphine is a drug approved by the US Food and Drug Administration that can be used, alongside behavioral therapies and counseling, to help with the treatment of opioid addiction. It is the "first medication to treat opioid dependency that is permitted to be prescribed or dispensed in physician offices, significantly increasing treatment access," according to the US Substance Abuse and Mental Health Services Administration.Banta-Green believes that creating better access to substance abuse disorder treatments, along with a better national understanding that these are treatable medical conditions, would help reduce the number of overdose-related deaths in the US. This includes giving more people access to medications that could help treat and manage opiate addiction."That's really fundamentally what I think we need to take away from these data finding is that there are solutions, other countries have them, and we are not doing the dramatic things that we need to be doing," he said. 3565