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The first large head-to-head comparison of two opioid addiction medications found that, although they were equally effective in getting people off of high levels of opioids, users had a significantly more difficult time starting a regimen of naltrexone, compared with buprenorphine.Buprenorphine is commonly known by the the brand name Suboxone, and naltrexone is sold under the brand name Vivitrol.The study, published Tuesday in the Lancet, looked at 570 patients with opioid addiction at eight inpatient treatment centers across the country for 24 weeks. Half of the group was assigned to naltrexone and the other half to bupenorphine.Six percent of those enlisted to use buprenorphine were unable to start their treatment, whereas 28% of those assigned to naltrexone dropped out before starting the therapy. 824

The Democratic National Committee contacted the FBI on Tuesday after it detected what it believes was the beginning of a sophisticated attempt to hack into its voter database, a Democratic source tells CNN.The DNC was alerted in the early hours of Tuesday morning by a cloud service provider and a security research firm that a fake login page had been created in an attempt to gather usernames and passwords that would allow access to the party's database, the source said.The page was designed to look like the access page Democratic Party officials and campaigns across the country use to log into a service called Votebuilder, which hosts the database, the source said, adding the DNC believed it was designed to trick people into handing over their login details.The source said the DNC is investigating who may have been responsible for the attempted attack, but that it has no reason to believe its voter file was accessed or altered.The DNC's chief security officer Bob Lord, a former Yahoo! executive, briefed Democrats on the attempted attack at a meeting of the Association of State Democratic Committees in Chicago on Wednesday.CNN has reached out to the FBI for comment.Early Tuesday morning, Microsoft announced that parts of an operation linked to Russian military intelligence targeting the US Senate and conservative think tanks that advocated for tougher policies against Russia were thwarted last week.That disclosure, coming less than three months ahead of the 2018 midterms, demonstrated Russia's continued efforts to destabilize US institutions. The news also places additional pressure on President Donald Trump to take action, even though he downplayed Russia's involvement as recently as Monday.The-CNN-Wire 1740

The European leg of Lady Gaga's "Joanne World Tour" has been postponed as the singer grapples with health issues, Live Nation announced Monday.In a statement posted on the promoter's site,?Live Nation revealed that the portion of the tour that was set to begin September 21 in Barcelona, Spain, and conclude on October 28 in Cologne, Germany, has been postponed until 2018."Lady Gaga is suffering from severe physical pain that has impacted her ability to perform," the statement read. "She remains under the care of expert medical professionals who recommended the postponement earlier today." 602

The Creek Fire in Central Californa continues to rage out of control nearly a week after it started.In Fresno County Tuesday, authorities helped rescue 142 people who had been trapped by the flames.CBS News reports that rescue officials were forced to make eight rescue trips on Tuesday.One person was found dead, but officials say that person died from natural causes unrelated to the fire.The Creek Fire had grown to more than 152,000 acres and was still 0% contained as of Tuesday evening. CBS News reports that the fire has destroyed more than 80 structures, including 60 homes.Firefighters battling the Creek Fire have had to deal with low humidity and high wind gusts in recent days — weather conditions that will likely carry through until Thursday.The Creek Fire is one of 11 large wildfires that the California Department of Forestry and Fire Protection. September typically marks the beginning of wildfire season in western states. 949

The Broadway League, the trade association that regulates theater performances in New York City, has said that all performances have been suspended until at least June 2021.Anyone with tickets to Broadway shows before June 2021 "should contact their point of purchase" about exchanges and refunds, the association said.“With nearly 97,000 workers who rely on Broadway for their livelihood and an annual economic impact of .8 billion to the city, our membership is committed to re-opening as soon as conditions permit us to do so. We are working tirelessly with multiple partners on sustaining the industry once we raise our curtains again,” Charlotte St. Martin the President of the Broadway League, said in a statement.Broadway shows in New York have been shut down since March 12, when the COVID-19 pandemic began to take hold in the city. In May, Broadway League initially suspended all performances through Septemeber before extending the shutdown through the end of the year in June. 999