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JUPITER, Fla. — Groundbreaking research out of the Scripps Research Institute in Jupiter, Florida found a genetic explanation for the pain processing and sensory issues some children living with autism face."To see the biology in the lab turn out that has parallels to what’s going on in these children takes it so far beyond just an academic endeavor," said Dr. Gavin Rumbaugh, a neuroscientist at Scripps. "You go home every day thinking, unbelievably, I may actually be making a difference in someone's life."One of those children who Rumbaugh hopes to help with his research is 10-year-old Beckett, who lives in Texas."We wanted to understand generally in the lab how genes like SYNGAP1 affect the way the brain functions and we thought what better way was then to look and see how this gene may directly affect sensory processing, and then further on ask the question, 'Does the change in sensory processing actually lead directly to learning, memory and behavioral impairment?' " he said.Beckett has a genetic mutation of SYNGAP1, which researchers have now found causes certain issues he faces, particularly, having an extremely high pain threshold while also experiencing heightened sensitivity to another kind of stimuli. Beckett and other children living with this genetic mutation also often have epilepsy."It's all about quality of life. Everybody deserves to live their best life and that's my mission," said Monica Weldon, Beckett's mom.Weldon said the research being done in Jupiter could change her son's life and the lives of hundreds of other children around the world with the same genetic abnormality and symptoms, some of whom whose families she's connected with online."That is the power I believe of a patient group that is motivated to find treatments for their loved ones," Weldon said. "Also, you've got scientists who are listening. They're willing to listen and they're willing to learn."The next step in Rumbaugh's research is to look at treating the symptoms from the genetic mutation. 2043
JERUSALEM (AP) — Israeli archaeologists have announced the discovery of a trove of early Islamic gold coins during recent salvage excavations near the central city of Yavne. The collection of 425 complete gold coins, most dating to the Abbasid period around 1,100 years ago, is an "extremely rare" find. Israel Antiquities Authorities archaeologists said on Monday that the discovery was among the largest caches of ancient coins found in Israel. In 2015, amateur divers found around 2,000 gold coins off the coast of the ancient port city of Caesarea dating to the Fatimid period in the 10th and 11th centuries. 620
JULIAN, Calif. (KGTV) - Headed to the snow this week? The San Diego County Sheriff’s Department wants to make sure you’re prepared for crowds.Snow fell in higher-elevations East County communities Wednesday, leading to the possibility of more families from low-lying areas traveling to the mountains.Deputies recommend you have a full tank of gas, water and food in case you’re stranded in traffic. Some areas may also require snow chains.CHECK WEATHER / CHECK TRAFFICAnyone who wants to play in the snow should respect private property fences and signs, deputies say.Parking in the mountains is limited. Violations will be enforced and citations issued by the Sheriff’s department. 695
JAMUL, Calif. (KGTV) - Neighbors are calling for more safety measures after surveillance video captured a fiery collision at an intersection in Jamul.A week ago, just before 5 p.m., Marc Burnett was opening up his off-road racing shop along Campo Road, when he heard it."I heard the skid marks hitting, and then I heard the boom," said Burnett.He ran outside and was greeted by flames."I just saw flames in the air. I saw a lot of flames. I saw the guy on the ground. He was on fire," said Burnett.Burnett raced back inside."I got the fire extinguisher, and had to put the motorcycle out -- and him," said Burnett.Burnett says the motorcycle driver, a man in his 30s, suffered serious burns to his hands and legs, but survived."He was very lucky that he survived," said Burnett.Burnett even more amazed when he looked at his surveillance video.In it you can see the truck pulling into the intersection from Maxfield Road and stop, before the eastbound motorcycle slams into the side of the truck, exploding into flames."Very scary to see that video. Didn’t know it was that bad until I saw it," said Burnett.Sadly, it was not unfamiliar.Burnett, who’s been in the area for more than 15 years, says he’s seen the aftermath of some eight serious accidents at that intersection, including a person killed crossing the road."It’s kind of a blind turn ... People coming out where the truck coming out ... It's hard to judge," said Burnett.Burnett is now lobbying for a traffic light at that intersection, which is often busy with casino traffic."Drivers are passing semi trucks on the turn. It's dangerous. If there was a light, people would have to slow down," said Burnett.The CHP says they investigation into the accident is ongoing.ABC 10News reached out to county officials about the neighbors' concerns and are waiting to hear back. 1841
JAMUL, Calif. (KGTV) - Some fire victims in Jamul are bracing for a potential power shutoff and more fire danger as the Santa Ana winds move in.A charred landscape marks what was once a picturesque Hidden Haven Farms. Co-owner Ryan Skidmore says his family got the call from SDG&E on Tuesday night, warning of a potential shutoff."Honestly it is was, 'here we go again.' We just got done with this," said Skidmore.Back in September, the Valley Fire decimated the 16-year-old farm known for sustainable farming. The Skidmores lost most of their crops and irrigation lines, along with 125 chickens.The family had tried to get wildfire insurance but was denied, partly because the farm is in a wildfire-prone area. Their total loss was more than 0,000.While several buildings were destroyed, seven others are still standing, including two homes. When the winds pick up, Skidmore will worry."There's flammable material on adjacent properties, and it could always come onto our property and burn what didn’t burn the first time," said Skidmore.Skidmore spent Wednesday hand trimming brush near structures. He'll also be checking his backup power sources, in case the power is shut off. Without power, they can't pump water from their wells."We have three different generators. A big one for the main house and smaller ones for tools and outbuildings," said Skidmore.With their power plans in place, Skidmore says they will settle in and brace for the wind."It's nerve-racking. The wind is so unpredictable," said Skidmore.Since the fires, neighbors have volunteered for cleanups and donated chickens and supplies. Skidmore says they are optimistic about their rebuild if they can avoid any more fires. 1711