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BEIJING, Sept. 9 (Xinhua) -- Lenovo Group, China's largest PC maker, said it aims to become the world's second-largest PC provider by the end of this year, China Daily reported Friday.The PC maker will take aggressive action to expand in the international PC market left by its competitors because of strategy adjustment, the English newspaper quoted Liu Chuanzhi, the board chairman of Lenovo, as saying.A few weeks ago, the world's biggest PC maker Hewlett-Packard Corp. said it will spin off its PC sector. Apple Inc's former CEO Steve Jobs resigned."The Chinese market is the starting point for Lenovo, but it won't be the only place Lenovo should put emphasis on. We will set up a more active strategy for expanding in overseas markets," Liu said.The PC maker has long been focusing on the global market. It purchased the PC division of the IBM Corp. a few years ago. In January, it announced a 175-million-U.S.-dollar joint venture with Japan's NEC Corp. In July, Lenovo completed its acquisition of Medion AG, a German multimedia and consumer electronics maker.
WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.
WASHINGTON, Sept. 15 (Xinhua) -- The rates of new lung cancer cases in the United States dropped among men in 35 states and among women in six states between 1999 and 2008, according to a report released Thursday by the Centers for Disease Control and Prevention (CDC).Among women, lung cancer incidence decreased nationwide between 2006 and 2008, after increasing steadily for decades.The decrease in lung cancer cases corresponds closely with smoking patterns across the nation, the report said. In the West, where smoking prevalence is lower among men and women than in other regions, lung cancer incidence is decreasing faster. Studies show declines in lung cancer rates can be seen as soon as five years after smoking rates decline.The report also noted that states that make greater investments in effective tobacco control strategies see larger reductions in smoking; and the longer they invest, the greater the savings in smoking -- related health care costs. Such strategies include higher tobacco prices, hard-hitting media campaigns, 100 percent smoke-free policies, and easily accessible quitting treatments and services for those who want to quit."Although lung cancer among men and women has decreased over the past few years," said CDC Director Thomas Frieden in a statement. "too many people continue to get sick and die from lung cancers, most of which are caused by smoking. The more we invest in proven tobacco control efforts, the fewer people will die from lung cancer."Lung cancer is the most commonly diagnosed cancer, and the leading cause of cancer death in the United States. Cigarette smoking and exposure to secondhand smoke cause most lung cancer deaths in the United States.
SAN FRANCISCO, Aug. 3 (Xinhua)-- Google's top legal officer on Wednesday posted a scathing blog post, accusing Microsoft, Apple, Oracle and other companies of waging "bogus" patent wars over smartphone technologies.More than 550,000 Android devices are activated daily, but the success of the mobile operating system has yielded "a hostile, organized campaign against Android by Microsoft, Oracle, Apple and other companies, waged through bogus patent," said Google Senior Vice President and Chief Legal Officer David Drummond."Microsoft and Apple have always been at each other's throats, so when they get into bed together you have to start wondering what's going on," wrote Drummond at the beginning of the blog post under the heading "When patents attack Android."The top legal officer lashed out the coalition that Apple and Microsoft formed to buy Novell patents and Nortel patents.Last month, Google was outbid by the 4.5 billion bid made by the winning consortium of companies that includes Apple, Microsoft, Research in Motion, Sony, Ericsson and EMC on Canadian company Nortel Network's patent portfolio.The Nortel portfolio, which is in all of the companies'best legal interests, includes patents on 3G and 4G wireless networking, optics, voice processing, semiconductors and more.Last December, an unnamed consortium of companies, organized by Microsoft and including Apple, EMC and Oracle, also outbid Google for nearly 900 patents of software company Novell.Patent litigation between technology companies have been flaring up particularly over mobile devices and technology.Last August, Oracle accused Google of infringing on patents related to Java, which the database giant acquired when it took ownership of Sun Microsystems in early 2010.Microsoft is suing device makers who use Android, including Barnes & Noble, Motorola and HTC.Drummond wrote that "We're also looking at other ways to reduce the anti-competitive threats against Android by strengthening our own patent portfolio. Unless we act, consumers could face rising costs for Android devices -- and fewer choices for their next phone."
WASHINGTON, June 14 (Xinhua) -- Eating a low-carbohydrate, high- protein diet may reduce the risk of cancer and slow the growth of tumors already present, according to a study published Tuesday in Cancer Research, a journal of the American Association for Cancer Research.The study was conducted in mice, but the scientists involved agree that the strong biological findings are definitive enough that an effect in humans can be considered."This shows that something as simple as a change in diet can have an impact on cancer risk," said lead researcher Gerald Krystal, a scientist at the British Columbia Cancer Research Center.Krystal and his colleagues implanted various strains of mice with human tumor cells or with mouse tumor cells and assigned them to one of two diets. The first diet, a typical Western diet, contained about 55 percent carbohydrate, 23 percent protein and 22 percent fat. The second, which is somewhat like a South Beach diet but higher in protein, contained 15 percent carbohydrate, 58 percent protein and 26 percent fat. They found that the tumor cells grew consistently slower on the second diet.As well, mice genetically predisposed to breast cancer were put on these two diets and almost half of them on the Western diet developed breast cancer within their first year of life while none on the low-carbohydrate, high-protein diet did. Interestingly, only one on the Western diet reached a normal life span ( approximately 2 years), with 70 percent of them dying from cancer while only 30 percent of those on the low-carbohydrate diet developed cancer and more than half these mice reached or exceeded their normal life span.Krystal and colleagues also tested the effect of an mTOR inhibitor, which inhibits cell growth, and a COX-2 inhibitor, which reduces inflammation, on tumor development, and found these agents had an additive effect in the mice fed the low-carbohydrate, high-protein diet.When asked to speculate on the biological mechanism, Krystal said that tumor cells, unlike normal cells, need significantly more glucose to grow and thrive. Restricting carbohydrate intake can significantly limit blood glucose and insulin, a hormone that has been shown in many independent studies to promote tumor growth in both humans and mice.Furthermore, a low-carbohydrate, high-protein diet has the potential to both boost the ability of the immune system to kill cancer cells and prevent obesity, which leads to chronic inflammation and cancer.