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WASHINGTON, Jan. 19 (Xinhua) -- New research published this week in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.The study, led by investigators with the Ohio State University Comprehensive Cancer Center, shows that overexpression of two genes called MET and EGFR causes the deregulation of six microRNAs, and that this deregulation leads to gefitinib resistance.The findings support the development of agents that restore the levels of these microRNAs. It offers a new strategy for treating non-small cell lung cancer, which is responsible for about 85 percent of the 221,000 lung-cancer cases and 157,000 deaths that occur annually in the United States. It also suggests that measuring the expression levels of certain microRNAs -- those controlled by the MET gene -- might predict which lung-cancer cases are likely to be resistant to gefitinib.Epidermal growth factor receptor (EGFR) is frequently overexpressed in non-small cell lung cancer, and this leads to uncontrolled cell proliferation. Gefitinib selectively inhibits EGFR activation and triggers cancer cells to self-destruct by apoptosis. However, non-small cell lung cancer cells inevitably develop resistance to the drug. The study reveals how this resistance occurs."Our findings suggest that gefitinib resistance that is caused by MET overexpression is at least partly due to miRNA deregulation, " says principal investigator Carlo Croce.

BEIJING, Jan. 20 (Xinhua) -- China will regulate the production and sale of cosmetic colored contact lenses by including them in its list of items classified as "medical apparatus."Some people wear such non-corrective colored contacts to change or enhance eye color for cosmetic and fashion purposes.As these contacts are not for vision correction and medication purposes, they are currently off limits to the country's medical administration and regulators, said a statement published on the website of the State Food and Drug Administration on Thursday.However, with the increasingly popular use of cosmetic contacts, safety and quality problems due to the regulation loophole are likely to harm consumers' health, and the administration has decided to expand the current medical regulation on contact lenses to cover cosmetic ones, the statement said.It explained that the administration will soon issue a notice to ban the manufacture and sale of these contacts without proper registration and licenses.The statement also warned consumers of the risks of these contacts and suggested they carefully choose and use such products.

MANILA, Jan. 9 (Xinhua) -- Philippine telecommunication companies cut off the signal of mobile phones in parts of Manila where millions of people are expected to converge for the feast of the Black Nazarene on Monday.Philippine Deputy Presidential Spokesperson Abigail Valte said that the move was part of the precautionary measures that the government has been undertaking following terror threats."Malacanang (Palace) confirms that the government asked the telcoms to temporarily disconnect their services in the route of the Black Nazarene procession as part of the security measures agreed upon during the meeting on Sunday," she said in a regular news briefing.She said that the disruption in mobile services would last for the entire duration of the procession of the Black Nazarene.She admitted that the signal of the cellular phones was disconnected in the past, and terrorists used the mobile phones as triggering device for bombs.Asked if the government considered the possible losses of telecommunication firms due to the disconnection of signals, Valte said, "as holders of a franchise, the public safety is paramount."President Benigno Aquino III personally warned on Sunday the public to be cautious in joining the feast of the Black Nazarene amid possible terrorist attacks. The government is expecting 9 million devotees to participate in the celebration.The Black Nazarene is the patron saint of Quiapo church. The statue was brought to Manila by a Spanish priest in 1607. It was aboard a ship that caught fire, the image was burned, and it came to be known as the "Black Nazarene" which people have since decided to preserve and honor.

TEHRAN, Oct. 9 (Xinhua) -- Iran is going to launch domestically- built Navid satellite by Safir satellite launcher by the end of March 2012, the semi-official Mehr news agency reported on Sunday.Navid (promise) is a research satellite and is currently undergoing pre-launch tests, said the report without further details.In June, Iran put the Rasad (surveillance) satellite in the orbit to render images to the country.Iran put a satellite into orbit in 2009 and sent some small animals into space in 2010. It plans to send man into space by 2020.