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SAN DIEGO (KGTV) — Sure, it may not be Torrey Pines, but Liberty Station's Loma Club is considered a great golf course in its own unique way.For beginners, the club is the perfect, reasonably priced way to get on the green. For veterans, a no frills way to work on your game."It's short, it's inexpensive, and it's well kept," Fred Leipold, an avid Loma Club golfer, told 10News.Lauren Gomez first played at the club when she was just a toddler. Now, she tees off with a scholarship to Pepperdine University in her back pocket. "I know a lot of kids come out here to practice. There's not a lot of golf courses around here, so it's really important to Point Loma," Gomez said.More than a century of history sits in the club's soil. At one time, a young Phil Mickelson played tournament at what was then called Sail Ho.Which is why players and locals were shocked to learn the Loma Club put out a notice that it will close in late December.Point Loma residents flooded social media following the news, worried that the same thing could happen in other nearby communities: Golf courses shutting down with plans to fill the land with housing. Residents from Escondido to Chula Vista have all seen long battles with developers."I think somebody's going to recognize the importance. You really can't tear this out," golfer Rick Gomez said. "It's too perfect."For the time being, those fears were put to rest, after a spokesperson with Pendulum Property Partners, who owns the Loma Club property, said the site would remain a golf course. The notice was issued after they were unable to reach a new lease deal with the current course operator: 1646
SAN DIEGO (KGTV) — The California Coastal Commission Wednesday signed off on a demonstration of the lighting project that would illuminate pillars of the Coronado Bay Bridge.The project will include installing lights along four pillars of the bridge, which will be tested during one week in June. Following the test, an environmental impact study will be conducted.The tests are part of a larger effort for a proposed artist-designed lighting project that would span 30 pillars of the 2.12-mile bridge. The Port of San Diego is trying to raise between - million to complete the project by 2022.At completion, the Port hopes to have a finished lighting display by artist Peter Fink, meant to serve as a gateway to the region and in a variety of scenarios using its programmable LED displays. Several sections of the bridge were illuminated last April during a study of the project. 894

SAN DIEGO (KGTV) - The floral tributes shut down by the pandemic, blossomed into reality Memorial Day at several national cemeteries.Susan Williams first met Gregory Torres in 1973 while he was in the Air Force navigator training program. While the relationship didn't last, she never forgot him."Funny, smart and dedicated. One of the best people I've ever known," said Williams, 71.In 1978, while stationed in Germany, Captain Torres died when his plane crashed during a training flight. He was buried at Fort Rosecrans National Cemetery.Williams, who lives in South Carolina, had plans to visit his grave this Memorial Day before the pandemic hit.Covid-19 also turned the usual local services virtual. The flags laid out by the cemetery and flowers put out by a national nonprofit wouldn't happen this year."It made me feel crummy. He should be remembered in some way," said Williams.Enter Jenelle Brinneman, a Valley Center florist who started a Gofundme campaign. After a 10news story, the campaign took off. Some ,000 and countless roses, Brinneman and a small group of volunteers spent the morning of Memorial Day laying a single rose at some 4000 grave markers between Fort Rosecrans and Miramar cemeteries."We're laying down these roses and people are crying, thanking us. Just so cool to be part of this. The feeling is just overwhelming," said Brinneman.Brinneman's group also set down 200 bouquets at gravestones, special requests submitted for Memorial Day. One of those requests came from Williams. "I'm just thrilled these people are doing this and he was honored," said Williams.Brinneman says the response was so incredible, she's hoping to make this an annual tradition. 1698
SAN DIEGO (KGTV) - The family of a man reported missing from a Spring Valley care facility two weeks ago told 10News Friday he was found safe in North Park.Aldofo Otanez, who has schizophrenia, lived at Mi Casa es Su Casa. His family said he was planning to visit his brother on February 16 but never arrived.Otanez’ brother said the family passed out flyers and posted pictures on social media.RELATED: Schizophrenic man still missing after two weeksOn Friday, a 10News viewer called the family to say Otanez had been sleeping on the sidewalk on El Cajon Blvd. in North Park.People at Dave’s Flower Box had given him a bottle of water, money to buy coffee, and a burrito.The family says he was hungry but is doing well. 738
SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223
来源:资阳报