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SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) - Looking for more space for your money? The Del Cerro and Torrey Highlands are the best San Diego neighborhoods for renters, according to HotPads.Analysts evaluated rental size and price per square foot. San Diego’s median rental size is 1,154 feet, and renters can expect to spend .32 per square foot of space.The median rental size in Torrey Highlands is 2,033 square feet, at .14 per square foot, HotPads reported. Del Cerro residents pay .77 per square foot, with a median rental size of 1,710 square feet. Rancho Pe?asquitos, Miramar Ranch North (Scripps Ranch), and the South Bay neighborhood of Ocean Crest are also in the top five communities with the most space for the money.RELATED: Report: San Diego seeing housing price cutsLas Vegas, a top destination for San Diegans who choose to leave the city, has some of the largest rentals and the most affordable rents. Raleigh, North Carolina, is also a good value, according to HotPads analysts.Denver and Boston have the smallest rentals for the money, averaging about 1,050 square feet. By comparison, Los Angeles and San Francisco average at 1,200 square feet.Size matters, but not as much as price. A Zillow Group Consumer Housing Trends Report showed 82 percent of renters named affordability as a top concern, 42 percent said finding the right size rental was extremely or very important.RELATED: The 10 fastest-growing metro areas 1431

SAN DIEGO (KGTV) - Lifeguards removed a body found floating in the ocean off Sunset Cliffs Friday morning, according to San Diego Fire-Rescue.First responders were notified about 9:30 a.m. about the remains near Point Loma Ave. Lifeguards removed the body and transported it to their headquarters, officials said.The person had been in the water “a while”, according to San Diego Police.Officers told 10News they would be handling the discovery as a death report and not sending a homicide team to investigate.The person's identity and cause of death were not immediately available. 590

SAN DIEGO (KGTV) — Memorial Day serves as a day to stop and remember those service members who have given the ultimate sacrifice.In San Diego, several memorial cemeteries will hold services to honor and commemorate these individuals.Elsewhere throughout the weekend, San Diegans will celebrate those freedoms ensured by military members with Memorial Day weekend events around town.Here's a look at Memorial Day services and events:ServicesFort Rosecrans Memorial DayWhen: May 27; When: Where: Fort Rosecrans National CemeteryA Memorial Day service will be held at Fort Rosecrans to honor fallen service men and women starting at 10 a.m. La Vista Memorial Park Memorial DayWhen: May 27; Where: La Vista Memorial ParkBeginning at 1 p.m., a Memorial Day service will be held at La Vista Memorial Park and Mortuary. Public officials on hand will be serving lunch.Mt. Soledad Memorial Day CeremonyWhen: May 27; Where: Mt. SoledadMemorial Day service will be held at Mt. Soledad at 2 p.m., with a special plaque presentation honoring Doris "Dorie" Miller, the first African-American Navy Cross recipient, awarded for his actions during Pearl Harbor.EventsPort of San Diego Festival of the SeaWhen: May 25 - 27; Where: San Diego Maritime MuseumFor the first time, the Port of San Diego is celebrating the sea and San Diego's 250th anniversary with a new community festival on the waterfront. Festival of the Sea features live performances, an artwork exhibition, and (for the older crew) a special on-board pub on the HMS Surprise.Legacy WeekWhen: May 24 - 27; Where: USS Midway MuseumLegacy Week marks San Diego's Memorial Day commemorations with a wreath laying ceremony, family activities, interactive exhibits, benefit concert with Daughtry, and more for the family, all from the USS Midway Museum. 1804

SAN DIEGO (KGTV) — It's going to be a great weekend to get outside and enjoy the fall season in San Diego!Believe it or not, the Christmas season has already begun as the Old Globe Theatre brings "Dr. Suess's How the Grinch Stole Christmas" back to the stage. Tickets are on sale for show times throughout the month!Also, SnowJam takes over Del Mar this weekend, packing heavily discounted and new gear and clothing, lift tickets, and more into the Del Mar Fairgrounds just before snow hits the slopes.Not interested in anything here? Check out the 10News?community events calendar for a look at even more things to do!Beer and food fans get their fill as well, with San Diego Beer Week continuing, Stone's DRK Festival, and the San Diego Bay Wine and Food Festival!Plus, Veteran's Day festivities hit town in celebration of our armed forces! Here's a look at what's happening this weekend:THURSDAYDr. Suess's How the Grinch Stole ChristmasWhere: Old Globe Theater; Cost: - (Runs Thursday - Sunday) That's right. The Grinch is back in San Diego! The Old Globe's production of "How the Grinch Stole Christmas" returns, bringing the classic Christmas tale of the Grinch's plan to ruin Whoville's holiday fun to the stage. San Diego Asian Film FestivalWhere: Various locations; Cost: - (Runs Thursday - Sunday) Enjoy San Diego's showcase of Asian American and international works of cinema as the San Diego Asian Film Festival this weekend! The festival brings an opening night party on Thursday followed by short film screening and special presentations! FRIDAYStone DRK FestivalWhere: Stone Brewery, Escondido; Cost: Fan on the dark brews? Stone, while known for its IPAs, is celebrating its darker pours during Stone DRK Festival. A ticket gets beer fans tasters, a commemorative glass, and tastes of some of the breweries favorite and rare beers! SnowJam?Ski & Snowboard ExpoWhere: Del Mar Fairgrounds; Cost: - (Runs Friday - Sunday) The latest and greatest in snow gear is waiting at Del Mar this weekend, as SnowJam comes to town. Check out heavily discounted, brand new equipment and clothing and lift tickets, and check out live demonstrations or talk with industry reps. Just in time for ski season!  SATURDAYSan Diego Veteran's Day ParadeWhere: San Diego Embarcadero; Cost: FreeCelebrate our nation's veterans and active-duty military members during San Diego's annual Veteran's Day parade! Service members will travel down Pacific Highway, past the USS Midway, in celebration of our nation's heroes. San Diego Beer WeekWhere: Various locations; Cost: Varies(Runs Friday - Sunday) Local craft beer fans can visit participating restaurants, bars, and breweries for special beer releases and events highlighting why San Diego is considered the capital of craft beer. 6th annual Ride the Point 2018Where: Oggi's Pizza and Brewing, San Diego; Cost: - Pedal for a cause along Point Loma in support of pancreatic cancer research! The annual Jim Krause Memorial Charity Bicycle Ride starts at Liberty Station and takes riders on a scenic path through Point Loma. The public is also invited to the race's free healthy lifestyle expo at the event!  SUNDAYSilver Strand Half Marathon & Veteran's Day 5KWhere: Sunset Park, Coronado; Cost: - Show your support for our nation's military during the Silver Strand Half Marathon! The run starts and finishes at Imperial Beach Pier Plaza, and treats runners and walkers to a post-race beach party and beer garden at the end! BOOmont Park and Fall FestWhere: Belmont Park; Cost: Free - Halloween may be over but Fall fun is still here! Belmont Park will continue its Boomont Park and Fall Fest this weekend, with free trick-or-treating, costume contests, entertainment, pumpkin painting, and much more. San Diego Bay Wine and Food FestivalWhere: Embarcadero Marina Park North; Cost: 5 - 5Treat your taste buds to bites from more than 60 celebrity chefs and restaurants, and sips from hundreds of wines and spirits during San Diego Bay Wine and Food Fest! San Diego's top chefs will be churning out delicious creations over the course of an entire week. 4261

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