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WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.

BEIJING, Oct. 26 (Xinhuanet) -- The question, why the first documented supernova was super-sized and grew so fast, has puzzled astronomers for centuries. Now it is solved by US researchers.The supernova, an exploded star, was observed in 185 A.D. and documented as a mysterious "guest star" by Chinese astronomers. It was visible for eight months.Scientists later found the supernova, 8,000 light years away, was a bigger-than-expected supernova remnant. BBC reported that if the infrared light it emits could be seen by human eyes, it would appear to be as large as the full Moon in the sky.Through observations in space telescopes, researchers of a latest study revealed that the explosion took place in a cavity in space, which allowed the star's remains to travel out much faster and farther. The study was published online in the Astrophysical Journal Monday.The supernova was "two to three times bigger than we would expect for a supernova that was witnessed exploding nearly 2,000 years ago. Now, we've been able to finally pinpoint the cause," stated Brian Williams, lead author of the study and an astronomer at North Carolina State University in Raleigh.

BEIJING, Dec. 31 (Xinhua) -- In a New Year's address broadcast on Saturday, Chinese President Hu Jintao vowed that China will continue to develop friendly exchanges with other countries and positively participate in international cooperation on global issues.While addressing domestic and overseas audiences via state TV and radio broadcasters, Hu urged the acceleration of the transformation of the country's economic development pattern and structural adjustments while making more efforts in ensuring people's livelihood.The country will continue to balance maintaining steady and relatively fast economic growth with adjusting its economic structures and managing inflation expectations, he said in the speech titled "Jointly Improve World Peace and Development," which was broadcast by China Radio International, China National Radio and China Central Television.A photo released on Dec. 31, 2011 shows Chinese President Hu Jintao delivering a New Year address, titled "Jointly Improve World Peace and Development", to domestic and overseas audiences via state TV and radio broadcasters.China will stick to the guidelines of "one country, two systems," "Hong Kong people governing Hong Kong," "Macao people governing Macao," and a high degree of autonomy in maintaining the long-term prosperity and stability of Hong Kong and Macao, Hu said."We will adhere to the principles of 'peaceful reunification' and 'one country, two systems,' continue to push forward the peaceful development of cross-Strait relations, ensure the basic benefits for those of the Chinese nationality, and endlessly work for the common benefit of the compatriots on both sides of the Taiwan Strait," he said.2011 was the first year of the country's 12th Five-Year Plan period (2011-2015). In the face of complicated international situations and arduous tasks in maintaining domestic reform, development and stability, Chinese people united and continued to push forward the opening up and reform drive and the socialist modernization construction, while maintaining steady and relatively fast economic growth and making progress in building a well-off society in an all-around way, he said.China was also actively engaged in international cooperation to boost the growth of the global economy and financial stability, and it was involved in resolving international and regional issues, he said.The world is currently witnessing multipolarization and globalization, and various countries are increasingly interdependent, Hu said."However, the instability and uncertainty of the world economic recovery is on the rise, international and regional hot-topic issues have cropped up one after another, and the peace and development of the world faces unprecedented opportunities and challenges," Hu said.China will stick to peace, development and cooperation, adhere to independent foreign policy, maintain world peace and promote common development, Hu said.The country will stick to the principle of mutual benefit when opening itself up, he said."We will develop friendly cooperations with all countries on the basis of the five principles of peaceful co-existence, and we will continue to actively participate in international cooperation on global issues," Hu said."I believe that as long as people from all countries make efforts hand-in-hand, the world will have a better future and the welfare of the people of all countries will improve," Hu said.An article by Hu on boosting the country's cultural development will be published in Qiu Shi (Seeking Truth), an official magazine of the Communist Party of China Central Committee, on Jan. 1.

ADDIS ABABA, Nov. 2 (Xinhua) -- Ethiopia will host the 13th World Congress on Public Health (WCPH) in April 2012, the Ethiopian Public Health Association (EPHA) said on Wednesday.The meeting will be held on April 23-27 under the theme: "Moving towards Global Health Equity- Opportunities and Treats".Speaking on the 22nd annual meeting of EPHA held here on Wednesday EPHA President Tewabech Bishaw said about 3,000 participants, including public health students from all over the world are expected to take part in the meeting.He said that preparations are well underway to successfully conduct the meeting.

WELLINGTON, Oct. 17 (Xinhua) -- Parents wanting to help their children avoid asthma and other allergies are being told to give their toys a frosty reception by sticking them in the freezer.Medical scientists in New Zealand and Taiwan have discovered that freezing children's soft toys can kill almost all house dust mites (HDMs), the microscopic bugs associated with a range of allergies, including asthma.Other effective remedies for killing HDMs, commonly found in children's soft toys, were tumble drying and washing with eucalyptus oil and detergent, the scientists from New Zealand's University of Otago and Taiwan's Changhua Christian Hospital found.HDMs were strongly associated with the development of asthma in children, and the severity of asthma was in proportion to the number of house dust mites a child was exposed to when sleeping with soft toys, said a statement from the university Monday."Children frequently sleep with their favorite toys close to their airways and this may be important for HDM-sensitized asthmatic children," said University of Otago Associate Professor Rob Siebers.The scientists tested the three different cleaning methods on 36 toys divided into three groups of 12.Freezing toys for at least 16 hours at minus 15 degrees centigrade resulted in a 95-percent reduction of HDMs, as did soaking in an emulsion of eucalyptus oil and liquid detergent for one hour before rinsing and drying.Hot tumble drying for one hour reduced mites by 89 percent, the study found."Washing and soaking with eucalyptus oil and detergent is very effective in not only reducing live mites, but also reducing house dust mite allergens, compared to freezing and tumble drying," said Siebers.Ten of the 12 toys cleaned this way showed no live mites at all.Siebers said all three methods were more effective than just washing toys, because water needed to be above 55 degrees centigrade to kill HDMs, but this usually damaged the toys."My advice for parents is to either tumble dry for one hour, or freeze the soft toy overnight, and then wash it in a cold wash to remove any allergens."Siebers said the thickness of the material used in making the toys could alter the effectiveness of the three methods.The scientists would conduct further research to determine how quickly HDMs recolonized soft toys and how often toys should be treated.The study has been published in the European journal, Paediatric Allergy and Immunology.