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TOKYO, Jan. 24 (Xinhua) -- Japanese Foreign Minister Koichiro Gemba said Tuesday that Japan will seek to take a less inward- looking stance when it comes to diplomacy in the Asia-Pacific region.Specifically he said that Japan will look to enhance diplomatic ties with China based on mutually beneficial goals."With China, this year marks the 40th anniversary of normalizing diplomatic ties. We will aim to deepen the mutually beneficial relationship based on common strategic interests," Gemba said Tuesday in his first foreign policy speech in parliament.He went on to say that Japan plans to proactively make " concrete efforts" to strengthen its ties with China and establish more "open and multilayered networks" in the best interests of both countries.

NEW YORK, Oct. 14 (Xinhua) -- The iPhone 4S went on sale at Apple store on the Fifth Avenue of Manhattan in New York early Friday.An Apple store worker said people were waiting outside the store around 3 p.m. Thursday and underwent an overnight rain for an early purchase of the smart phone which started sale at 8 a.m. Friday.About 200 people were seen lining up outside the store and some of them said they would like to pay tribute to Steve Jobs, Apple's longtime CEO who died of pancreatic cancer at the age of 56 on Oct. 5."I'm a Steve's fan, iPhone 4S is the best of Steve's work. I am not going to buy iPhone 5,"Jim Bedford, who is in his 30s, said. "Maybe this is my last iPhone," he added.People left a Steve's picture, flowers and apples on the sidewalk to pay respect to Apple's co-founder. Some apples were seen inscribed such words as "Nice job" and "We will always remember you."Tom White, 50, said he had iPhone 1 and 3 and "now is the time to change a new one."The iPhone 4S is operated seven times faster than their predecessor and features an upgraded camera. Apple reported more than 1 million pre-orders for the iPhone 4S, breaking a mark set by last year's model. The phone also went on sale Friday in six other countries -- Britain,Germany,France,Australia, Canada and Japan.

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

BEIJING, Otc. 26 (Xinhuanet) -- The more coffee people consume, the less likely they develop the most common form of skin cancer, a new study suggests, according to media reports Tuesday."Our study indicates that coffee consumption may be an important option to help prevent basal cell carcinoma," stated Fengju Song, lead researcher of the study and a postdoctoral fellow in the department of dermatology at Brigham and Women's Hospital and Harvard Medical School in Boston.Basal cell carcinoma (BCC) is reported to be a slow-growing form of skin cancer that accounts for 75 percent of all skin cancers. It is the most common type of skin cancer, with nearly one million new cases diagnosed each year in the United States.Although BCC is hardly fatal, if ignored, there may be consequences of treatment, including disfigurement, according to a USA Today report.The US researchers found that women who drank over three cups of coffee a day were 20 percent less likely to develop BCC, whereas the risk of having BCC for men who consumed more than three cups per day lowered 9 percent.To get the findings, the researchers analysed data from almost113,000 people between1984-2008 and over 23,000 were diagnosed with BCC.The researchers agreed that caffeinated coffee was associated with BCC risk reduction, but decaffeinated coffee did not have such effect.According to a Fox News report, besides cutting the risk of skin cancer, coffee consumption has also been found to lower the risk of breast cancer and prostate cancer and cancer overall."To the best of our knowledge, coffee consumption is a healthy habit," said Fengju Song, cited by the Fox News.The findings were presented Monday at the American Association for Cancer Research International Conference in Boston and not yet published in a scientific journal.

BEIJING, Sept. 30 (Xinhuanet) -- Miners, construction workers and people in hotel and food service industry are most likely to smoke in the U.S., according to new research finding.The finding was contained in a report released Thursday by the U.S. Centers for Disease Control and Prevention (CDC).According to the finding, miners and people in hotel and food service have a cigarette smoking rate of 30 percent, followed closely by construction workers' 29.7 percent.Both rates are much higher than the average smoking rate of 19.6 percent among all U.S. working adults.Workers in the education services industry have the lowest smoking rate, with 9.7 percent, followed by the 10.9 percent of workers in company management, the report said.Low education levels are a factor in high smoking rates, along with poverty and gender, said Ann Malarcher, senior scientific adviser at the CDC."Although some progress has been made in reducing smoking prevalence among working adults," the report wrote, "additional effective employer interventions need to be implemented."Smoking kills an estimated 443,000 each year in the U.S., costing about 193 billion U.S. dollars annually in direct health care expenses and productivity loss.