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SAN DIEGO (KGTV) — A Sorrento Valley company is working to create an implant that will help people kick their addiction to both opioids and alcohol.BioCorRx, based in Orange County, is developing the implant. They chose San Diego-based Irisys Therapeutics to help them build it."It’s not going to fix the opioid crisis," says BioCorRx CEO Brady Granier. "But it’s going to be another tool in a tool chest of those people looking for another solution and one that will help them get through the cravings."The implant uses Naltrexone, a drug already approved by the FDA as an every-day pill or a once-per-month shot. Naltrexone blocks receptors in the brain so that opioids or alcohol won't have any effect on people who use them. It also helps curb cravings."As long as it’s blocking the receptor, the opioids come in, and they can’t engage with that receptor to give you the euphoria or the respiratory depression that leads to overdose," says Granier. "It’s protecting you."Granier says creating an implant that lasts three months will make it more likely that people will be able to beat their addition. The implant, named BICX102, would be implanted into a person's stomach fat and dissolve slowly over three months."The goal is to give someone a longer period of time to address those issues without the intrusive cravings coming in," he says. "A lot of behavioral changes can take place in 90 days that you can’t do in 30."Granier's company just received a .7 million grant from the National Institute on Drug Abuse. It will last two years, which Granier says will fund the research through the development of the implant and some early testing.He's hoping to start human testing by 2020.Granier says implants like the one he is hoping to create are already available in other countries. But the FDA has yet to approve one in the US, where standards are more strict."The first pellet you make needs to be exactly the same as the 10,000th," he says. "It has to be a precise process."It's personal for Granier, who has family members with addiction in their past. He also worked as a nurse before starting his company. Granier says he saw the destructive effects of addiction every day. Now he's hoping to find a solution."It’s rare to find a good opportunity where you can make a social impact and be an entrepreneur at the same time," he says. 2358
SAN DIEGO (KGTV) — A San Diego Police officer is showing his gratitude this holiday season after an incredible display of heroism.It was at the end of his graveyard shift when he heard panic over the scanner."It's moving pretty quick, ooohh standby. It went over the… it went over the cliff. I was not in pursuit. Send medics!" a San Diego Police Lieutenant said over the police scanner.San Diego Police K9 handler, Jonathan Wiese, noticed that this incident was just around the corner to where he was.RELATED:Officer rescues toddlers after father drives off Sunset CliffsPolice: Man drives off Sunset Cliffs with twin daughters in truckOn the morning of June 13, 2020, a suicidal man had driven through a guard rail at Sunset Cliffs. His truck plunged into the ocean. Inside were his twin 2-year-old daughters."We didn't even come up with a plan. I just pretty much said 'I'm going,'" Wiese remembered.He rappelled down a 30-foot drop, MacGyvering a rescue rope with his 100-foot dog leash. He says adrenaline, police training, but mostly his father-instinct kicked in."I had a two-year-old daughter at home, so when I'm looking in the water, it's her who is floating in the water," Wiese said. "So now it's just, 'OK, you're getting down this cliff!'"RELATED: San Diego officer honored for heroic acts in Poway synagogue shootingThe husband and father of two swam to the crash site and hoisted the girls to safety. His brave actions have since been recognized many times. He says it is a day he will always remember."I am most grateful this year, knowing that those two little girls have a second chance at life," Wiese said.Another unforgettable day for Wiese is April 27, 2019. He was on his way to get lunch with his family when he heard an active shooter call on the scanner. Moments later, he spotted the suspect. Without backup, he convinced the Poway Synagogue shooter to surrender. Officer Wiese took him into custody.Wiese says his competitive spirit motivates him to be a better version of himself every day, to show resilience and strength for his community."If you feel like you're going to win, then incidents like this, like at Sunset Cliffs, 'I'm going to win this incident. I'm going to save these girls in this man.' At the synagogue, 'I'm going to win. I'm going to go home to my family, and he is going to go to jail. and the community is going to be safe.'" Wiese said. 2399

SAN DIEGO (KGTV) - A woman's trip to Mission Bay ended with her, and her car, soaked.The woman, who identified herself as Candy, said she was next to her car on a boat ramp preparing to unload her kayak for a day of fishing and roaming around Mission Bay. Suddenly, her 2002 Audi convertible started rolling as she was unloading gear.Candy jumped into the car and road it into the bay as she tried to get her emergency brake to engage."It just wouldn't. It just kept on going," Candy told 10News. "I was standing straight up in it as it was going down ... quite a scene, I'm sure."The car started sinking into the bay with Candy still inside, before she jumped out to swim back to shore. Her lunch and kayak floated to the other side of the bay as her car became completely submerged, she told 10News."I'm going to have plenty of fish now," she joked. "It's not a big deal, things happen."Two tow trucks were able to fish Candy's vehicle out of the bay and San Diego Lifeguards retrieved her car and kayak, in which she had left her purse and lunch.Candy said she had just purchased the car in November.San Diego Lifeguards reminded locals to exercise caution while using boat ramps. 1216
SAN DIEGO (KGTV) - A team of scientists at UC San Diego is getting into the beach business."We looked around and said 'what's the most important thing that we could possibly make?" said Biology Professor Stephen Mayfield. "And that answer is obvious. Flip flops and surfboards."Much more important than the products themselves is what they are made of. Mayfield wants to make plastic products out of more sustainable materials than the traditional petroleum. He says extracting the oil from algae is a much cleaner process. And because it is biodegradable, old and worn-out flip-flops and surfboards won't sit in landfills for thousands of years.The surfboards are virtually indistinguishable from traditional boards, and only cost about five dollars more. Mayfield says about a dozen professional surfers are already using algae boards in worldwide competition.His team at UCSD is working with a local manufacturer to bring the boards to market. Mayfield expects them to be ready by the end of spring.The flip flops are currently in the prototype stage. Mayfield plans to distribute several pairs to UCSD students this summer for testing. He hopes they will be ready for sale to the public by next year."My dream would be if we could make all the flip-flops in the world out of this material. This would have an enormous benefit to the planet."Mayfield's team are experimenting with the chemistry to control how quickly the flip-flops will biodegrade. His plan is to engineer them to last the same as a standard flip-flop. 1531
SAN DIEGO (KGTV) - A San Diego woman known for helping others got the gift of a new smile Wednesday.Twyla Green got a life-changing surgery and a new set of teeth as the lucky winner of the Smile Again program."You can do anything as long as you put your mind to it,” Green said. “God sends people that will help you.”The initiative, hosted by Oral Surgery and Dental Implant Specialists of San Diego, offers the community suffering from poor oral health the opportunity to apply a free ,000 smile.They tell 10News Twyla was selected out of more than 200 San Diegans.Twyla says she’s lived her life taking care of other people; this opportunity is a way to help allow her to feel the confidence she helps others achieve. 731
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